Digital audio broadcasting method and apparatus using complementary pattern-mapped convolutional codes

ABSTRACT

A method of transmitting digital information comprises the steps of forward error correcting a plurality of bits of digital information using complementary pattern-mapped convolutional codes, modulating a plurality of carrier signals with the forward error corrected bits, and transmitting the carrier signals. The modulation can include the step of independently amplitude shift keying in-phase and quadrature components of the QAM constellation using Gray code constellation points corresponding to amplitude levels. Transmitters that transmit signals in accordance with the method and receivers that receivers such signals are also included.

BACKGROUND OF THE INVENTION

[0001] This invention relates to methods and apparatus for coding digital information and more particularly to such methods and apparatus for use in digital audio broadcasting systems

[0002] Digital Audio Broadcasting (DAB) is a medium for providing digital-quality audio, superior to existing analog broadcasting formats. Both AM and FM In-Band On-Channel (IBOC) DAB signals can be transmitted in a hybrid format where the digitally modulated signal coexists with the currently broadcast analog signal, or in an all-digital format without the analog signal. IBOC DAB requires no new spectral allocations because the digitally modulated signal and the analog signal are simultaneously transmitted within the spectral mask of an existing channel allocation. IBOC DAB promotes economy of spectrum while enabling broadcasters to supply digital quality audio to their present base of listeners.

[0003] An orthogonal frequency division multiplex (OFDM) technique has been described for IBOC DAB. OFDM signals include orthogonally spaced carriers modulated at a common symbol rate. The frequency spacing for symbol pulses (e.g., BPSK, QPSK, 8PSK or QAM) is proportional to the symbol rate. For hybrid IBOC transmission of AM compatible DAB signals, sets of OFDM sub-carriers are placed within about 5 kHz to 15 kHz on either side of a coexisting analog AM carrier, and additional OFDM sub-carriers are placed within a ±5 kHz frequency band occupied by the analog modulated AM carrier.

[0004] DAB systems utilize forward error correction (FEC) and interleaving to improve the reliability of the transmitted digital information over corrupted channels. Most conventional convolutional codes have been designed to perform well with binary signaling in an additive white noise Gaussian (AWGN) channel. The simplest codes have rate of 1/n, where each input information bit produces n output bits. Punctured codes can be constructed by removing code bits from a rate 1/N “mother code” to produce a higher rate code. S.

[0005] Kallel, “Complementary Punctured Convolutional (CPC) Codes and Their Applications,” IEEE Trans. Comm., Vol. 43, No. 6, pp. 2005-2009, June 1995, described a technique for producing complementary codes, which employs a sort of puncturing technique to create good component codes.

[0006] B. Kroeger, D. Cammarata, “Robust Modem and Coding Techniques for FM Hybrid IBOC DAB,” IEEE Trans. on Broadcasting, Vol. 43, No. 4, pp. 412-420, December 1997 described a technique to create overlapping component codes without all of Kallel's requirements on the complementary property. In U.S. patent application Ser. No. 09/438,822 (WIPO International Publication No. WO 01/35555), Kroeger et al. have also shown that these codes can be mapped onto QAM symbols using a Pragmatic Trellis Code Modulation (PTCM) technique described by Viterbi et al., in “A Pragmatic Approach to Trellis-Coded Modulation”, A. Viterbi et al. IEEE Communications Magazine, pp. 11-19, Vol. 27, No. 7, July 1989, while also preserving the complementary-like properties.

[0007] The free distance (dfree) of a convolutional code (punctured or non-punctured) is a convenient metric to gauge error correction performance in an AWGN channel with binary signaling (e.g. BPSK or QPSK). Secondary metrics such as the number of paths at the free distance, and the number of errors on those paths are used to resolve finer performance differences. The Optimum Distance Profile is also useful, especially for codes with large constraint length. When nonbinary signaling is used, such as QAM in an AWGN channel, the minimum Euclidean distance metric through the trellis paths is significantly more appropriate. Unfortunately trellis code modulation (TCM) and PTCM were designed for AWGN channels and do not perform well in impulsive noise. This is because the PTCM (or TCM) codes provide no error protection on the most significant bits with the larger uncoded Euclidean distances in the QAM constellation. Hamming distance is more important for error protection in an impulsive noise channel.

[0008] There is a need for a coding technique that overcomes these limitations and is suitable for use in IBOC DAB systems.

SUMMARY OF THE INVENTION

[0009] This invention provides a method of transmitting digital information comprising the steps of forward error correcting a plurality of bits of digital information using complementary pattern-mapped convolutional codes, modulating a plurality of carrier signals with the forward error corrected bits, and transmitting the carrier signals.

[0010] Forward error correction can be accomplished by defining a plurality of code partitions, selecting a puncture size compatible with the partitions, finding noncatastrophic partition codes, and mapping in-phase and quadrature components of the noncatastrophic codes to a QAM constellation. The modulation preferably includes the step of independently amplitude shift keying in-phase and quadrature components of the QAM constellation using Gray code amplitude levels.

[0011] Forward error correction can also include the steps of deleting predetermined bits in the plurality of bits to produce a modified plurality of bits, allocating the modified plurality of bits among a plurality of partitions, and mapping in-phase and quadrature components of the modified plurality of bits to a QAM constellation.

[0012] The invention also encompasses transmitters comprising means for forward error correcting a plurality of bits of digital information using complementary pattern-mapped convolutional codes, means for modulating a plurality of carrier signals with the forward error corrected bits, and means for transmitting the carrier signals.

[0013] Another aspect of the invention includes a method of receiving an information signal comprising the steps of receiving a plurality of carrier signals modulated by a plurality of complementary pattern-mapped convolutional coded bits, demodulating the carrier signals to recover the complementary pattern-mapped convolutional coded bits, and producing an output signal based on the complementary pattern-mapped convolutional coded bits. The demodulating steps can include the step of passing the complementary pattern-mapped convolutional coded bits through a nonlinear limiter.

[0014] The invention further encompasses receivers for receiving an information signal comprising means for receiving a plurality of carrier signals modulated by a plurality of complementary pattern-mapped convolutional coded bits, means for demodulating the carrier signals to recover the complementary pattern-mapped convolutional coded bits, and means for producing an output signal based on the complementary pattern-mapped convolutional coded bits.

[0015] The invention overcomes the limitations of prior art pragmatic trellis coded modulation by exploiting the contribution of each bit in the puncture pattern toward the code free distance when these bits are assigned nonbinary values, related to the Euclidean distance of the bits mapped to the signaling constellation.

BRIEF DESCRIPTION OF THE DRAWINGS

[0016]FIG. 1 is a schematic representation of the subcarrier assignments for a hybrid AM in-band on-channel digital audio broadcasting system;

[0017]FIG. 2 is a schematic representation of the subcarrier assignments for an all-digital in-band on-channel digital audio broadcasting system;

[0018]FIG. 3 is a simplified block diagram of relevant portions of an IBOC DAB transmitter which can incorporate the method of the present invention;

[0019]FIG. 4 is a block diagram illustrating the functionality of a forward error correction (FEC) interleaver for a core layer of a 30 kHz AM IBOC system;

[0020]FIG. 5 is a block diagram illustrating the functionality of a forward error correction (FEC) interleaver for a hybrid enhancement layer of a 30 kHz AM IBOC system;

[0021]FIG. 6 is a block diagram illustrating the functionality of an all-digital enhancement layer of 30 kHz AM IBOC system;

[0022]FIG. 7 is a block diagram illustrating the functionality of a forward error correction (FEC) interleaver for an integrated digital services (IDS) channel in an AM IBOC system;

[0023]FIG. 8 is a simplified block diagram of relevant portions of an IBOC DAB receiver which can receive signals coded in accordance with the method of the present invention;

[0024]FIG. 9 is a block diagram illustrating the functionality of an AM IBOC hybrid deinterleaver and FEC decoder implementation that permits rapid acquisition of the core audio;

[0025]FIG. 10 is a block diagram illustrating the functionality of another AM IBOC hybrid deinterleaver and FEC decoder implementation that permits rapid acquisition of the core audio;

[0026]FIG. 11 is a schematic representation of a robust soft metric F(y) for an eight-amplitude shift keying (8-ASK), in-phase or quadrature component of a 64-quadrature amplitude modulated (64-QAM) signal;

[0027]FIG. 12 is a schematic representation of a robust soft metric F(y) for a four-amplitude shift keying (4-ASK), in-phase or quadrature component of a 16 quadrature amplitude modulated (16-QAM) signal; and

[0028]FIG. 13 is a schematic representation of a robust soft metric F(y) for a binary phase shift keying (BPSK), in-phase or quadrature component of a quadrature phase shift keying (QPSK) signal.

DESCRIPTION OF THE PREFERRED EMBODIMENTS

[0029] This invention provides a Forward Error Correction (FEC) technique that can be utilized in AM compatible IBOC (In-Band On-Channel) DAB (Digital Audio Broadcast) systems. This FEC technique is referred to herein as Complementary Pattern-mapped Trellis-Coded Modulation (CPTCM). The CPTCM coding is designed to accommodate the likely interference scenarios encountered in an AM IBOC DAB channel.

[0030] Referring to the drawings, FIG. 1 is a schematic representation of the subcarrier assignments for a hybrid AM in-band on-channel (IBOC) digital audio broadcasting system. The hybrid IBOC DAB signal 10 includes a main carrier 12 at frequency f_(o), that is analog modulated by a program signal in accordance with conventional AM broadcasting techniques. The signal also includes a plurality of evenly spaced subcarriers that are transmitted in the same channel as the analog modulated signal. First and second groups of subcarriers are positioned in upper and lower sidebands 14 and 16, respectively, and are referred to as the core subcarriers. A third group of subcarriers, referred to as enhancement subcarriers, is located in a central band 18, that is also occupied by the analog modulated carrier. The subcarriers in the first and second groups are modulated both in-phase and in quadrature with respect to the analog modulated carrier. The subcarriers in the third group are arranged in complementary pairs and modulated in quadrature with the analog modulated carrier. Two subcarriers 20 and 22 of the third group that lie closest to the center of the channel are referred to as timing subcarriers and are modulated using BPSK modulation. A digital audio broadcasting system that utilizes complementary carriers is disclosed in U.S. Pat. No. 5,859,876, which is hereby incorporated by reference.

[0031]FIG. 2 is a schematic representation of the subcarrier assignments for an all-digital in-band on-channel (IBOC) digital audio broadcasting system. The all-digital IBOC DAB signal 30 includes first and second groups 32 and 34 of evenly spaced subcarriers, referred to as the core subcarriers, that are positioned in upper and lower sidebands 36 and 38. Third and fourth groups 40 and 42 of subcarriers, referred to as enhancement subcarriers, are also positioned in upper and lower sidebands 36 and 38. Two timing subcarriers 44 and 46 of the third group that lie closest to the center of the channel and are modulated using BPSK modulation.

[0032] The AM IBOC DAB signal is digitally modulated using COFDM (Coded Orthogonal Frequency Division Multiplexing). Each of the subcarriers is modulated using 64-QAM symbols. The digital information (e.g. audio) is interleaved in partitions, and then FEC coded using complementary pattern-mapped trellis coded modulation (CPTCM). The CPTCM method of forward error correction (FEC) is based upon a combination of a new code pattern-mapping technique, and application of Complementary Punctured Codes to IBOC DAB systems, expanding the complementary-like properties to two dimensions.

[0033] The basic requirements for the CPTCM code in IBOC DAB systems, include the ability to puncture the original code in various overlapping partitions including Main, Backup, Lower Sideband and Upper Sideband. Each of the four overlapping partitions must survive as a good code. The Lower and Upper Sidebands should be optimized as a pair of complementary non-overlapping partitions. Similarly, the Backup and Main partitions should survive independently. Of course, all partitions should be noncatastrophic codes. A digital audio broadcasting system that uses partitioning is disclosed in the previously mentioned U.S. patent application Ser. No. 09/438,822, and is hereby incorporated by reference.

[0034]FIG. 3 is a simplified block diagram of relevant portions of an IBOC DAB transmitter 50 which can incorporate the method of the present invention. The transmitter includes an audio encoder 52 that receives a sampled audio signal on line 54. The encoded signal on line 54 is subjected to forward error correction as illustrated by FEC encoder 56. The resulting forward error corrected signal on line 58 is then interleaved as illustrated by interleaver 60. Modulator 62 modulates the interleaved signal. In the hybrid system, a sampled audio source 64 supplies and AM signal to summation point 66 where the AM signal on line 68 and the digitally modulated signal on line 70 are combined to produce a composite signal on line 72 that is then modulated by modulator 74 and broadcast through antenna 76. It will be recognized that although the functions shown in FIG. 3 are shown in separate blocks, the functions can be performed using one or more processors, where multiple functions are performed in one processor.

[0035]FIG. 4 is a functional block diagram illustrating a forward error correction (FEC) interleaver 80 for a core layer of a 30 kHz AM IBOC system. A digital signal is supplied on line 82 and assembled into a modem frame core containing, for example, 3000 bits, as illustrated by block 84. The modem frame is then divided into a plurality of bit groups as illustrated by block 86, wherein the modem frame is shown to be divided into 6000 5-bit groups. The groups are then subjected to forward error encoding and puncturing as illustrated by block 88.

[0036] Punctured convolutional codes are derived from a rate 1/N “mother code”, by removal of some of the code bits. The punctured code bits can be identified in a puncture pattern, which repeats periodically. The puncture period P is the number of information bits in the puncture pattern. The total number of bits in the puncture pattern is P N. The resulting code rate of the punctured code is: ${\frac{k}{n} = \frac{P}{{P \cdot N} - x}};$

[0037] where x is the number of punctured code bits.

[0038] The particular bits to be punctured should be chosen carefully to minimize the loss in error correction performance of the resulting punctured code. Further, it is important to avoid creating a catastrophic code by puncturing. For example the removal of one particular bit may result in a free distance loss of 1, while removal of a different bit may result in a loss of 3, and the removal of yet a different bit may result in a catastrophic code. Clearly, all code bit locations in the puncture pattern do not contribute equally to the error correction performance of the punctured code. This property can be exploited in the mapping of code bits to nonbinary signaling such as ASK or QAM.

[0039] In the example illustrated in FIG. 4, each of the 5-bit groups results in a 12-bit output. The 12-bit groups are then partitioned into main-upper, main-lower, backup-upper and backup-lower partitions as illustrated by blocks 90, 92, 94 and 96, for example by allocating three bits of each 12-bit group to each of the partitions. The backup-upper and backup-lower bits are delayed as illustrated by blocks 98 and 100, and the bits are mapped into a core interleaver as shown by block 102.

[0040]FIG. 5 is a functional block diagram illustrating forward error correction (FEC) for an enhancement interleaver 104 for an AM hybrid IBOC system. A digital signal is supplied on line 106 and assembled into a modem frame core containing, for example, 24000 bits, as illustrated by block 108. The modem frame is then divided into a plurality of bit groups as illustrated by block 110, wherein the modem frame is shown to be divided into 4000 6-bit groups. The groups are then subjected to forward error encoding and puncturing as illustrated by block 112. In the example, each of the 6-bit groups results in a 12-bit output. The 12-bit groups are then partitioned into enhancement-upper and enhancement-lower partitions as illustrated by blocks 114 and 116, for example by allocating six bits of each 12-bit group to each of the partitions. The enhancement-upper and enhancement-lower bits are delayed as illustrated by blocks 118 and 120, and the bits are mapped into an enhancement interleaver as shown by block 122. FIG. 6 is a functional block diagram illustrating a forward error correction (FEC) interleaver 124 for an enhancement layer of an all-digital AM IBOC system. A digital signal is supplied on line 126 and assembled into a modem frame core containing, for example, 3000 bits, as illustrated by block 128. The modem frame is then divided into a plurality of bit groups as illustrated by block 130, wherein the modem frame is shown to be divided into 6000 5-bit groups. The groups are then subjected to forward error encoding and puncturing as illustrated by block 132. In the example of FIG. 6, each of the 5-bit groups results in a 12-bit output. The 12-bit groups are then partitioned into main-upper, main-lower, backup-upper and backup-lower partitions as illustrated by blocks 134, 136, 138 and 140, for example by allocating three bits of each 12-bit group to each of the partitions. The backup-upper and backup-lower bits are delayed as illustrated by blocks 142 and 144, and the bits are mapped into a core interleaver as shown by block 146.

[0041]FIG. 7 is a functional block diagram illustrating forward error correction (FEC) for an integrated data service (IDS) interleaver 148 for an AM hybrid IBOC system. A digital signal is supplied on line 150 and assembled into a modem frame core containing, for example, 80 bits, as illustrated by block 152. The modem frame is then divided into a plurality of bit groups as illustrated by block 154, wherein the modem frame is shown to be divided into ten 8-bit groups. The groups are then subjected to forward error encoding and puncturing as illustrated by block 156. In the example, each of the 8-bit groups results in a 24-bit output. The 24-bit groups are then partitioned into IDS-upper and IDS-lower partitions as illustrated by blocks 158 and 160, for example by allocating six bits of each 12-bit group to each of the partitions. The IDS-upper and IDS-lower bits are then mapped into an enhancement interleaver as shown by block 162.

[0042]FIG. 8 is a simplified block diagram of relevant portions of an IBOC DAB receiver 170 which can receive signals coded in accordance with the method of the present invention. The composite broadcast signal is received by antenna 172 and converted to an intermediate frequency (IF) signal on line 174 by front end circuit 176. The IF signal is then processed by a digital down converter 178 that includes an analog to digital converter 180 and a processor that performs mixing, decimation and filtering as illustrated by block 182 to produce a complex baseband signal on line 184. An automatic gain control 186 feeds the baseband signal back to a multiplier 188 in the digital down converter. Demodulator 190 demodulates the analog modulated portion of the complex baseband signal and demodulator 192 demodulates the digitally modulated portion of the complex baseband signal. After deinterleaving, FEC decoding, and audio decoding as illustrated by blocks 194 and 196, the resulting DAB stereo signal on line 198 and the analog signal on line 200 are blended as illustrated by block 202 to produce an audio output on line 204.

[0043]FIG. 9 is a functional block diagram of an AM IBOC hybrid deinterleaver and FEC decoder. The interleaved and forward error corrected core signal is input on line 206 and demodulated into in-phase (I) and quadrature (Q) components as illustrated in block 208. Block 210 shows that soft decisions for the I and Q components are determined and the I and Q soft decisions are deinterleaved in blocks 212 and 214 respectively. The deinterleaved quadrature components for the main upper and main lower partitions are delayed as illustrated by block 216, and the deinterleaved forward error corrected core signals are decoded as illustrated by block 218 to produce the core data on line 220.

[0044] The interleaved and forward error corrected enhancement signal is input on line 222 and demodulated into in-phase (I) and quadrature (Q) components as illustrated in block 224. Block 226 shows that soft decisions for the I and Q components are determined, and the I and Q soft decisions are deinterleaved in block 228. The deinterleaved enhancement signals are forward error correction decoded as illustrated by block 230 to produce the enhancement data on line 232.

[0045] The interleaved and forward error corrected IDS signal is input on line 234 and demodulated into in-phase (I) and quadrature (Q) components as illustrated in block 236. Block 238 shows that soft decisions for the I and Q components are determined, and the I and Q soft decisions are deinterleaved in block 240. The deinterleaved forward error corrected IDS signals are decoded as illustrated by block 242 to produce the integrated data service data on line 244.

[0046]FIG. 10 is a functional block diagram of an alternative AM IBOC hybrid deinterleaver and FEC decoder. The interleaved and forward error corrected core signal is input on line 246 and demodulated into in-phase (I) and quadrature (Q) components as illustrated in block 248. Block 250 shows that soft decisions for the I and Q components are determined, and the I and Q soft decisions are deinterleaved in blocks 252 and 254 respectively. The deinterleaved quadrature components for the main upper and main lower partitions are delayed as illustrated by block 256, and the deinterleaved forward error corrected core signals are decoded as illustrated by block 258 to produce the core data on line 260.

[0047] The interleaved and forward error corrected enhancement signal is input on line 262 and demodulated into in-phase (I) and quadrature (Q) components as illustrated in block 264. Block 266 shows that soft decisions for the I and Q components are determined and the I and Q soft decisions are deinterleaved in blocks 268 and 270 respectively. The deinterleaved quadrature components for the main upper and main lower partitions are delayed as illustrated by block 272, and the deinterleaved enhancement signals are forward error correction decoded as illustrated by block 274 to produce the enhancement data on line 276.

[0048] The interleaved and forward error corrected IDS signal is input on line 278 and demodulated into in-phase (I) and quadrature (Q) components as illustrated in block 280.

[0049] Block 282 shows that soft decisions for the I and Q components are determined, and the I and Q soft decisions are deinterleaved in block 284. The deinterleaved forward error corrected IDS signals are decoded as illustrated by block 286 to produce the IDS data on line 288.

[0050] Designing the CPTCM code is a multi-step process. First the partitions are defined, for example Main, Backup, Lower, and Upper partitions. In the coded orthogonal frequency division multiplexing (COFDM) example, the partitions are defined as groups of subcarriers that are affected together as a group by an interference scenario. Specifically, if coded subcarriers are placed on both the lower and upper sidebands, one of these sidebands can be corrupted by an interferer while the other sideband is expected to survive on its own. In other words, the code in each sideband should not be catastrophic, and should have good error correction properties on its own. Therefore each partition must constitute a code rate less than or equal to 1. Similarly a pair of partitions may be time diverse, where one partition is transmitted first (e.g. Main), and the other partition is transmitted several seconds later (e.g. Backup). In this case the signal can experience an outage for a second (e.g. as a receiver passes under a bridge) and either the Backup or Main partition will survive because they don't experience the outage over the same content information due to time diversity. Different pairs or sets of partitions can overlap. For example the Upper/Lower and Main/Backup partition pairs can overlap each other. More particularly, the Lower partition can be comprised of half of the Main partition bits plus half of the Backup partition bits, while the Upper partition comprises the remaining bits.

[0051] Next, a puncture pattern size (code rate and puncture period) is selected to accommodate the partitions. If a code is comprised of two mutually exclusive partitions (e.g. Main, Backup) each of code rate R. Then the composite code is rate R/2. The Mother code from which the partitions are formed by puncturing must have a rate no greater than R/2. Typically the Mother code is a convolutional code of rate 1/n. The partitions need not include sets of code bits that are mutually exclusive. The period of the puncture pattern must be sufficiently large to form each of the partitions.

[0052] Then noncatastrophic partition components are found, ideally with maximum free distance, dfree. This would involve a computer search, with possibly multiple good results and combinations from which to select.

[0053] For nonbinary code bit modulations, the best bit mapping for the possible noncatastrophic partitions would be determined. Binary modulation such as BPSK or QPSK does not benefit from the mapping of code bits to the modulation symbol. QAM is a nonbinary modulation where, in this code design, the in-phase (I) and quadrature phase (Q) components of the QAM symbol are treated individually as ASK symbols. Each ASK symbol carries b code bits forming an m-ary ASK symbol of m=2^(b) amplitude levels which are Gray-coded. This involves placing various soft weights on the bits, instead of hard-decision (±1). A method of determining a relative “soft” free distance is described below.

[0054] The best mappings compatible with the partitioning that yield the maximum “soft” dfree are then selected. Unfortunately, the ideal mappings of bits to symbols within each partition may not be consistent with the bit mapping in other partitions. For example, not all partitions can use the bits with the greatest average Euclidean distance. There are additional restrictions when partitions overlap. These restriction will likely result in a compromise in the bit mapping for each of the partitions. In some cases it may be desirable that one partition have a better mapping than another (e.g. Backup can be improved at the expense of Main performance).

[0055] The CPTCM technique is applied to a QAM symbol by treating the I and Q components as independently coded ASK signals. Specifically the 64-QAM symbol is created by modulating the I or Q component with independent 8-ASK signals. The 8-ASK symbols are generated from specially selected 3-bit groups which are then used to address the Gray-mapped constellation points. The Gray mapping maximizes performance by minimizing the number of decision boundaries in the ASK mapping. This maximizes the average Euclidean distance. This is clearly different from either the set partitioning suggested by Ungerboeck in “Channel Coding with Multilevel/Phase Signals,” IEEE Transactions on Information Theory, Vol. IT-28, No. 1, January 1982, pp. 55-67, or the multi-level coding and PTCM mapping suggested in the previously mentioned article by Viterbi et al. The mapping of the code bit triplets to the 8 levels of the 8-ASK symbols is presented in Table 1. TABLE 1 Mapping of CPTCM-coded bits to 8 levels of the 8-ASK symbols. Level Level Level Level Level Level Level Level MAPPING −3.5 −2.5 −1.5 −0.5 0.5 1.5 2.5 3.5 A 0 0 0 0 1 1 1 1 B 0 0 1 1 1 1 0 0 C 0 1 1 0 0 1 1 0

[0056] The 16-QAM symbol is created by modulating the I or Q components with independent 4-ASK signals. The 4-ASK symbols are generated from specially selected 2-bit groups which are then used to address the Gray-mapped constellation points. The mapping of the code bit pairs to the 4 levels of the 4-ASK symbols is presented in Table 2. TABLE 2 Mapping of CPTCM-coded bits to 4 levels of the 4-ASK symbols. Level Level Level Level MAPPING −1.5 −0.5 +0.5 +1.5 A 0 0 1 1 B 0 1 1 0

[0057] The mapping of the code bits to ASK levels is described next. Gray-code mapping is used to assign ASK levels to bit triplets or bit pairs. Gray mapping is a well-known method of assigning bits to address levels (ASK levels in this example) where the ordering of the levels requires the minimal number of changes of bits. Specifically, exactly one bit changes between the address of successive levels. In contrast, a binary number assignment of addresses has no such restriction. In the 8-ASK example, Gray coding results in 7 bit changes between the 8 levels, not counting the end points. A binary number ordering of levels involves 11 bit changes, not counting the endpoints.

[0058] Gray coding is known to be beneficial upon detection of the ASK signals in noise since the most likely bit estimation errors are made when the level is near a bit transition. It is further observed that more transitions (m/2) occur in the least significant bit (LSB) of the Gray-mapped m-ASK symbol, while only one transition occurs in the most significant bit (MSB). Therefore the LSB is more prone to errors caused by noise than the MSB. Thus the MSB is more reliable than the LSB, and the other bits are between these extremes. This property is exploited in the method of this invention.

[0059] In addition to exploiting the unequal error-correcting property of the code bits through puncturing, the invention also uses this property to map the code bits to the ASK symbols (bit address triplets or pairs). The most valuable code bits are placed in the most reliable MSB locations, and the least valuable bits in the LSB locations. This should tend to minimize the loss in error correcting ability of the resulting code and modulation. The main benefit of this technique over TCM or PTCM is that a good Hamming distance can be maintained. TCM or PTCM are designed to maximize Euclidean distance while allowing a Hamming distance of only 1 on the MSB's. Therefore the MSB's have no error protection which is unacceptable for impulsive noise and offers poor performance in fading. In contrast, the CPTCM technique proposed here is designed to maintain the good Hamming distance of the underlying binary code, while maximizing Euclidean distance under these constraints. Furthermore the CPTCM code is easy to implement since it requires only a single stage of decoding and deinterleaving, unlike the other multistage decoding/deinterleaving techniques of TCM or PTCM.

[0060] CPTCM requires an assessment of the relative value of the various code bits within the puncture pattern. For example assume there are 6 code bits in a partition remaining after puncturing the others, and these 6 bits are to be mapped to the bit triplets of the 8-ASK symbols used to create 64-QAM symbols. Then the 6 code bits are placed into 3 categories of reliability, where the most valuable 2 bits are associated with the 2 MSBs, the least valuable 2 bits are associated with the 2 LSBs, and the 2 middle bits are associated with the middle ASK address bits. It is not necessary that the bits are grouped within the same symbols since bit interleaving would be desirable to scatter the burst errors within a symbol.

[0061] Next the value of each code bit in a puncture pattern is assessed for subsequent mapping of the code bits to the modulation symbols. Either a code partition is identified or the entire code is used, depending on whether the mapping is to be optimized over each partition individually, or if it is more important to optimize the mapping over the entire code. These two different optimizations will generally yield different mapping results. In a case where it is preferred to optimize the individual partitions, the assessment of the value of the code bits can be done in several ways.

[0062] For example, each bit can be removed from the code and the loss in error correction ability can be assessed. In order of importance convenient metrics include catastrophic loss, free distance loss, increased number of paths at the distance. The least valuable bits result in the least loss. These bits would then be ranked to map the least valuable bits to the LSBs, or most vulnerable bits, in the modulation symbols. Alternatively, the bits can be removed in groups instead of one at a time. Another approach would be to use a Viterbi Algorithm to estimate some sort of soft free distance related to Euclidean distance of the code.

[0063] When code partitions overlap, generally a compromise must be made for the bit mapping. This is because one partition may prefer a particular bit to be mapped to a MSB modulation symbol address, while that same bit in an overlapping partition may prefer an LSB mapping. Both optimizations cannot be accommodated in these cases and a compromise must be evaluated and established.

[0064] Several example code designs are described next using the method(s) described above. These designs include interleaver designs intended for an AM IBOC system. The interleaver can be designed for CPTCM with a scalable (2-layer) audio codec. The interleaver would be comprised of 2 parts: a Core Interleaver spanning 50 subcarriers (25 Upper plus 25 Lower sideband) and an Enhancement Interleaver spanning 50 subcarriers (50 complementary subcarrier pairs for the Hybrid system, and 25 in each the lower and upper “wings” for the All-Digital system). Two additional subcarrier pairs (+−27 & +−53) in the Enhancement region can be used for IDS information and are independent of the Enhancement coding. In this example, subcarriers 2 through 82 on either side of the main carrier are utilized in the 30 kHz system. FIG. 1 illustrates the location of the interleaver partitions for the Hybrid system, while FIG. 2 illustrates the location of the interleaver partitions for the All-Digital system.

[0065] The CPTCM codes can be created through puncturing of rate ⅓ convolutional codes. A rate ⅓ code provides a sufficient number of bits in the puncture pattern to form a rate {fraction (5/12)} code used in the example described above. Although it is possible to use almost any code generator polynomials, a good place to start the search is to use the standard polynomials since they are more likely to produce better punctured codes. The FEC code requires appropriate puncture patterns and code-bit mapping to provide good results in both the Hybrid system and All-Digital system. For the Hybrid system, the puncture pattern would provide code bits for the upper sideband and lower sideband complementary components. Each sideband is required to provide a good quality code in the case of the other sideband being corrupted. The Core code must also be partitioned for diversity with Main and Backup components. Each complementary component can be coded using a rate ⅚ code producing a combined code rate of {fraction (5/12)}. The Core FEC puncture pattern would also be distributed between a Main audio channel and a Backup audio channel. The Backup channel is used for fast tuning and provides time diversity to mitigate the effects of intermittent blockages. The Main and Backup channels each can be coded at a rate of ⅚ resulting in a combined code rate of {fraction (5/12)}. The Upper/Lower partition pair overlaps the Main/Backup partition pair.

[0066] A good code including the two overlapping pairs of partitions was found using the Core FEC Composite Puncture Pattern generator polynomials G=[G1=561, G2=753, G3=711]. The combined Main, Backup, Upper, and Lower puncture pattern for the Core FEC code is defined in Table 3. Some examples of some good codes created using these techniques are described next. TABLE 3 Puncture Pattern. BLC MUB BLB BUA MLC BUB BLA MLB MLA BUC MUC 0 MUA 0 0

[0067] In Table 3, B=Backup, M=Main, L=Lower Sideband, U=Upper Sideband and A, B, and C are the bit positions. Table 4 provides a summary of the core code parameters. TABLE 4 Core FEC summary of parameters. Partition Rate d_(f) a c Main 5/6 4 5 54 Backup 5/6 5 19 168 Lower 5/6 5 19 168 Upper 5/6 4 5 28 Composite  5/12

[0068] The overall rate of the Hybrid Upper plus Lower Enhancement FEC code is rate ⅔. The puncture pattern and code-bit assignment is defined in Table 5. TABLE 5 Puncture Patterns. EL_(I) EU_(IA) EU_(IB) EU_(QA) 0 0 0 0 EL_(Q) 0 EU_(QB) 0

[0069] In Table 5, E=Extended, L=Lower Sideband, U=Upper Sideband, I=In-Phase, Q=Quadrature, and A and B=bit positions. The Hybrid Enhancement FEC Composite Puncture Pattern was produced using generators G=[G1=561, G2=753, G3=711]. Table 6 provides a summary of the hybrid enhancement code parameters. TABLE 6 Hybrid Enhancement FEC summary of parameters. Partition Rate d_(f) a c Upper 1 1  4 38 Lower 2 N/A Composite 2/3 7 20 96

[0070] The FEC coding for the All-Digital Enhancement can be identical to the Core code design. However there is a modification required in the interleaver for framing and delay. This modification is described below with respect to the All-Digital Enhancement interleaver.

[0071] The IDS subcarriers can be modulated using 16-QAM symbols as were the Enhancement subcarriers. Subcarriers 27 and 53 (−27 and −53 are complementary) are IDS subcarriers in the Hybrid system. Subcarriers 27 and −27 are noncomplementary IDS subcarriers in the All-Digital system. The IDS Sequence is 32 symbols long (symbols 0 through 31) and associated with a block length of 32 OFDM symbols in the particular interleaver used in this example. Symbols locations 10 and 26 are assigned as Training Symbols. The remaining 30 symbols carry 120 bits of rate ⅔ coded information. Hence each IDS Sequence carries 80 information bits, including an 8-bit CRC. A rate ⅓ code can be employed with rate ⅔ complementary components. The Upper and Lower complementary code components of the All-Digital IDS subcarriers correspond to the Hybrid inner and outer IDS complementary subcarrier pairs, respectively, of the Hybrid. Table 7 illustrates the all-digital IDS puncture pattern. TABLE 7 Puncture Pattern. IDSL_(IA0) IDSU_(IA1) IDSL_(IA1) IDSU_(IA2) IDSL_(QA0) IDSU_(QA1) IDSL_(QA1) IDSU_(QA2) IDSL_(IB0) IDSU_(IB0) IDSL_(IB2) IDSU_(IB2) IDSL_(QB0) IDSU_(QB0) IDSL_(QB2) IDSU_(QB2) IDSU_(IA0) IDSL_(IB1) IDSU_(IB1) IDSL_(IA2) IDSU_(QA0) IDSL_(QB1) IDSU_(QB1) IDSL_(QA2)

[0072] In Table 7, IDS=Integrated Data Service, L=Lower Sideband, U=Upper Sideband, I=In-phase, Q=Quadrature, and A and B are bit positions. The IDS FEC Composite Puncture Pattern was produced using generators G=[G1=561, G2=753, G3=711]. Table 8 provides a summary of the IDS code parameters. TABLE 8 Core FEC summary of parameters. Partition Rate d_(f) a c Upper 2/3 7 6 26 Lower 2/3 7 6 26 Composite 1/3 17 

[0073] An interleaver block can be comprised of 32 COFDM symbols (bauds). There would be 8 blocks in a Modem Frame (Interleaver span) for the Main and the Enhancement partitions. The Backup partition can be interleaved over only one block span to permit rapid tuning. The Core Interleaver includes an upper sideband and a lower sideband (25 subcarriers each). The Enhancement Interleaver also includes an upper sideband and a lower sideband (25 subcarriers each, excluding the IDS subcarriers) for the All-Digital system, or equivalently an Inner and Outer Enhancement partition for the Hybrid system. Each interleaver block holds a total of 800 QAM symbols (750 data+50 Training).

[0074] The scalable audio codec in this example is comprised of two layers (Core and Enhancement). The Core layer is mapped onto 50 QAM subcarriers (25 subcarriers on each sideband) while the Enhancement layer is mapped onto 50 QAM complementary subcarriers (pairs for Hybrid). The Core and Enhancement Layers are coded separately. In addition there are some subcarriers assigned to carry 16-QAM IDS data.

[0075] Interleaving within each block spanning 25 subcarriers and 32 OFDM symbols can be performed using the following expressions for the row and column indices: $\begin{matrix} {{{row}(k)} = {{mod}\left\lbrack {{{11 \cdot {{mod}\left( {{9 \cdot k},25} \right)}} + {16 \cdot {{floor}\left( \frac{k}{25} \right)}} + {11 \cdot {{floor}\left( \frac{k}{50} \right)}}},32} \right\rbrack}} \\ {{{col}\quad (k)} = {{mod}\quad\left\lbrack {{9 \cdot k},25} \right\rbrack}} \\ {k = {0\quad \ldots \quad 749}} \end{matrix}$

[0076] The index k points to one of the 750 QAM symbols within the block (Core or Enhancement). Each of the 64-QAM symbols of the Core carries 6 codes bits, which are mapped within a block. Similarly, each of the 16-QAM symbols of the Enhancement or IDS interleaver carries 4 codes bits which are mapped within blocks using the same expressions. Of the total of 800 symbols in a block, the remaining 50 QAM symbols are used for training symbols. The training symbols can be located in the last 50 QAM symbol locations (k=750 . . . 799). TABLE 9 Symbol Indices Within A Block; Training Symbol = “T”. 0 1 2 3 4 5 6 7 8 9 10 11 12 A =  0 0 “T” 728 692 631 595 534 498 437 376 340 279 243  1 150 114 53 17 “T” 745 684 648 587 526 490 429 393  2 300 264 203 167 106 70 9 “T” 737 676 640 579 543  3 450 414 353 317 256 220 159 123 62 1 “T” 729 693  4 600 564 503 467 406 370 309 273 212 151 115 54 18  5 “T” 714 653 617 556 520 459 423 362 301 265 204 168  6 125 89 28 “T” 706 670 609 573 512 451 415 354 318  7 275 239 178 142 81 45 “T” 723 662 601 565 504 468  8 425 389 328 292 231 195 134 98 37 “T” 715 654 618  9 575 539 478 442 381 345 284 248 187 126 90 29 “T” 10 725 689 628 592 531 495 434 398 337 276 240 179 143 11 50 14 “T” 742 681 645 584 548 487 426 390 329 293 12 200 164 103 67 6 “T” 734 698 637 576 540 479 443 13 350 314 253 217 156 120 59 23 “T” 726 690 629 593 14 500 464 403 367 306 270 209 173 112 51 15 “T” 743 15 650 614 553 517 456 420 359 323 262 201 165 104 68 16 25 “T” 703 667 605 570 509 473 412 351 315 254 218 17 175 139 78 42 “T” 720 659 623 562 501 465 404 368 18 325 289 228 192 131 95 34 “T” 712 651 615 554 518 19 475 439 378 342 281 245 134 148 87 26 “T” 704 668 20 625 589 528 492 431 395 334 298 237 176 140 79 43 21 “T” 739 678 642 581 545 484 448 387 326 290 229 193 22 100 64 3 “T” 731 695 634 598 537 476 440 379 343 23 250 214 153 117 56 20 “T” 748 687 626 590 529 493 24 400 364 303 267 206 170 109 73 12 “T” 740 679 643 25 550 514 453 417 356 320 259 223 162 101 65 4 “T” 26 700 664 603 567 506 470 409 373 312 251 215 154 118 27 75 39 “T” 717 656 620 559 523 462 401 365 304 268 28 225 189 128 92 31 “T” 709 673 612 551 515 454 418 29 375 339 278 242 181 145 84 48 “T” 701 665 604 568 30 525 489 428 392 331 295 234 198 137 76 40 “T” 718 31 675 639 578 542 481 445 384 348 287 226 190 129 93 13 14 15 16 17 18 19 20 21 22 23 24 A =  0 182 146 85 49 “T” 702 666 605 569 508 472 411  1 332 296 236 199 138 77 41 “T” 719 658 622 561  2 482 446 385 349 288 227 191 130 94 33 “T” 711  3 632 596 535 499 438 377 341 280 244 183 147 86  4 “T” 746 685 649 588 527 491 430 394 333 297 236  5 107 71 10 “T” 738 677 641 580 544 483 447 386  6 257 221 160 124 63 2 “T” 730 694 633 597 536  7 407 371 310 274 213 152 116 55 19 “T” 747 686  8 557 521 460 424 363 302 266 205 169 108 72 11  9 707 671 610 574 513 452 416 355 319 258 222 181 10 82 46 “T” 724 663 602 566 505 469 408 372 311 11 232 196 135 99 38 “T” 716 655 619 558 522 461 12 382 346 285 249 188 127 91 30 “T” 708 672 611 13 532 496 435 399 338 277 241 180 144 83 47 “T” 14 682 646 585 549 488 427 391 330 294 233 197 136 15 7 “T” 735 699 638 577 541 480 444 383 347 286 16 157 121 60 24 “T” 727 691 630 594 533 497 436 17 307 271 210 174 113 52 16 “T” 744 683 647 586 18 457 421 360 324 263 202 166 105 69 8 “T” 736 19 607 571 510 474 413 352 316 255 219 158 122 61 20 “T” 721 660 624 563 502 466 405 369 308 272 211 21 132 96 35 “T” 713 652 616 555 519 458 422 361 22 282 246 185 149 88 27 “T” 705 669 608 572 511 23 432 396 335 299 238 177 141 80 44 “T” 722 661 24 582 546 485 449 388 327 291 230 194 133 97 36 25 732 696 635 599 538 477 441 380 344 283 247 186 26 57 21 “T” 749 688 627 591 530 494 433 397 336 27 207 171 110 74 13 “T” 741 680 644 583 547 486 28 357 321 260 224 163 102 66 5 “T” 733 697 636 29 507 471 410 374 313 252 216 155 119 58 22 “T” 30 657 621 560 524 463 402 366 305 269 208 172 111 31 32 “T” 710 674 613 552 516 455 419 358 322 261

[0077] The 30000 Core information bits comprising each modem frame are coded and assembled in groups of bits from the puncture patterns, as defined previously and functionally illustrated in FIG. 4. These groupings are mapped into the Core Interleaver using the expressions presented in Table 10.

[0078] The Core Interleaver indices are defined as: k=Block Symbol Index, 0 to 749 symbols in each Core block; b=Block number, 0 to 7 within each Modem Frame; and p=PTCM bit mapping within each 64-QAM symbol, (IA=0, IB=1, IC=2, QA=3, QB=4, QC=5) TABLE 10 Core Interleaver Mapping N, n = p Partition 0 . . . N − k b I & Q, ASK X_(k,b,p) 1 index in block b block # mapping BU_(k,b,p) 18000 mod[n + floor(n/750), 750] floor(n/2250) mod(n,3) (see note 1) BL_(k,b,p) 18000 mod[n + floor(n/750) + 1, 750] floor(n/2250) mod(n,3) (see note 1) MU_(k,b,p) 18000 mod[n + floor(n/3000) + 2, 750] mod(3 * n,8) 3 + mod(n,3) ML_(k,b,p) 18000 mod[n + floor(n/3000) + 3, 750] mod(3 * n + 3,8) 3 + mod(n,3)

[0079] A diversity delay of three modem frames is added to the Backup signal.

[0080] The 24000 Enhancement information bits comprising each modem frame are coded and assembled in groups of bits from the puncture patterns, as defined previously and illustrated in FIG. 6. These groupings are mapped into the Enhancement Interleaver using the expressions presented in Table 11.

[0081] The Enhancement Interleaver indices k, b, p and p are defined as: k=Block Index, 0 to 750 symbols in each Core block; b=Block number, 0 to 7 within each Modem Frame; p=16-QAM bit mapping within each 16-QAM symbol, (IA=0, IB=1, QA=2, QB=3); and p=QPSK bit mapping within each QPSK symbol, (1=0, Q=1). TABLE 11 Hybrid Enhancement Interleaver Mapping. p I & Q, Partition N k b ASK X_(k,b,p) n = 0 . . . N − 1 index in block b block # mapping EU_(k,b,p) 24000 mod[n + floor(n/6000), mod[3 * n + floor(n/3000) + mod(n,4) 750] 2 * floor(n/12000), 8] EL_(k,b,p) 12000 mod[n + floor(n/6000), mod[3 * n + floor(n/3000), 8] mod(n,2) 750]

[0082] A diversity delay of 2 Modem Frames is added to the Backup signal.

[0083] The 30000 All-Digital Enhancement information bits comprising each modem frame are coded and assembled in groups of bits from the puncture patterns, as defined previously and illustrated in FIG. 7. These groupings are mapped into the All-Digital Enhancement Interleaver using the expressions presented in Table 12.

[0084] The All-Digital Enhancement interleaver in this example is very similar to the Core interleaver, except that the Backup portion interleaves on frame (not block) boundaries identical to the Main portion. This necessitates a minor modification to the Core interleaver. The Core Backup Block interleaving spans the I (in-phase) QAM component, while the Main Frame interleaving spans the Q (quadrature) QAM component. In order to accommodate Frame Enhancement interleaving, the Backup I (in-phase) interleaver is made identical to the Main Q interleaver expressions. Then the Enhancement Backup Frame must be transmitted one frame ahead of the Core Backup Frame, while the Main Core and Enhancement Frames are transmitted simultaneously.

[0085] The All-Digital Enhancement Interleaver indices k, b and p are defined as: k=Block Symbol Index, 0 to 749 symbols in each block; b=Block number, 0 to 7 within each Modem Frame; and p=PTCM bit mapping within each 64-QAM symbol, (IA=0, IB=1, IC=2, QA=3, QB=4, QC=5). TABLE 12 All-Digital Enhancement Interleaver Mapping. p Partition N, n = k b I & Q, ASK X_(k,b,p) 0 . . . N − 1 index in block b block # mapping BU_(k,b,p) 18000 mod[n + floor(n/3000) + 2, 750] mod(3 * n,8) mod(n,3) BL_(k,b,p) 18000 mod[n + floor(n/3000) + 3, 750] mod(3 * n + 3,8) mod(n,3) MU_(k,b,p) 18000 mod[n + floor(n/3000) + 2, 750] mod(3 * n,8) 3 + mod(n,3) ML_(k,b,p) 18000 mod[n + floor(n/3000) + 3, 750] mod(3 * n + 3,8) 3 + mod(n,3)

[0086] A diversity delay of 2 or 3 modem frames is added to the Backup signal.

[0087] The 80 IDS information bits comprising each block are coded and assembled in groups of bits from the puncture patterns, as defined previously and illustrated in FIG. 7. These groupings are mapped into the Enhancement Interleaver using the expressions presented in Table 13.

[0088] The IDS Interleaver Indices k and p are defined as: k=Block Index, 0 to 29 symbols in each block, skipping the two training symbols (8 and 24) of 32 total; and p=16-QAM bit mapping within each 16-QAM symbol, (IA=0, IB=1, QA=2, QB=3). TABLE 13 IDS Interleaver Mapping. N p Partition n = k I & Q, X_(k,p) 0 . . . N − 1 index in IDS sequence ASK mapping IDSU_(k,p) 120 mod(n + floor(n/60),30) mod(n,4) IDSL_(k,p) 120 mod(n + floor(n/60) + 11,30) mod(n,4)

[0089] Interleaving within each IDS sequence spanning 32 OFDM symbols can be performed using the following expression for the row (vector) index: $\begin{matrix} {{{row}(k)} = {{mod}\left\lbrack {{{11 \cdot \left( {k + {{floor}\left( \frac{k}{15} \right)}} \right)} + 3},32} \right\rbrack}} \\ {k = {0\quad \ldots \quad 29}} \end{matrix}$

[0090] The index k points to one of the 32 16-QAM symbols within the IDS sequence. Each of the 16-QAM symbols carries 4 code bits. Of the total of 32 symbols, 30 carry IDS information while the remaining 2 symbols are used for training symbols (locations 8 and 24).

[0091] A functional block diagram of the deinterleaver and FEC decoder portions of a receiver is shown in FIG. 9. The constellation data at the input is comprised of the I and Q values for each of the QAM symbols, which have been demodulated and normalized to the constellation grid. Channel State Information (CSI) is associated with each I and Q value to permit subsequent soft-decision detection of the bits. The purpose of the delay elements in the figure is to time-align the Backup audio information with the Main and Enhancement audio information, since the Main and Enhancement have been delayed at the transmitter. The MU and ML blocks of bits are accumulated in an entire modem frame prior to deinterleaving with the BU and BL blocks of bits. Blocks 208, 210, 212, 218, 236, 238, 240 and 242 in the figure indicate functions that must be processed on interleaver block boundaries (as opposed to modem frame boundaries) in order to minimize delay in processing the Backup or 111S data.

[0092] Since binary codes are used for CPTCM with nonbinary modulation, it is beneficial to obtain some sort of soft binary metrics from noisy M-ary symbols. Suppose that the received noise symbol is:

y _(i) =s _(i) +n _(i), i=1, . . . N

[0093] Assuming K information bits per symbol, the binary metric for the k-th bit is given by: ${\lambda_{i,k} = {{\ln \frac{\Pr \left( {b_{k} = \left. 1 \middle| y_{i} \right.} \right)}{\Pr \left( {b_{k} = \left. 0 \middle| y_{i} \right.} \right)}} = {\ln \frac{\underset{{all}\quad s_{j}^{1,k}}{\sum{f_{n}\left( {y_{i} - s_{j}^{1,k}} \right)}}}{\underset{{all}\quad s_{j}^{0,k}}{\sum{f_{n}\left( {y_{i} - s_{j}^{0,k}} \right)}}}}}},{k = 1},\ldots \quad,K$

[0094] where s_(j) ^(lk) stands for the j-th symbol in the constellation that has bit value 1 in the k-th bit position (and similarly for s_(j) ^(0,k), the j-th symbol in the constellation that has bit value 0 in the k-th bit) and ${f_{n}(x)} = {\frac{1}{\sqrt{2\quad \pi \quad \sigma^{2}}}{\exp \left\lbrack {- \frac{x^{2}}{2\quad \sigma^{2}}} \right\rbrack}}$

[0095] is the probability density function of the noise, assuming AWG noise. The above formula for the soft bit metric applies for any constellation. The main disadvantage of this approach is that it requires computations of exponentials. An approximate metric can be obtained by approximating the sum of exponentials by the maximum exponential, so that $\begin{matrix} {{\lambda_{i,k} \cong {\ln \frac{\max_{{all}\quad s_{j}^{1,k}}{\exp \left\lbrack {{- \frac{1}{2\sigma_{i}^{2}}}\left( {y_{i} - s_{j}^{1,k}} \right)^{2}} \right\rbrack}}{\max_{{all}\quad s_{j}^{0,k}}{\exp \left\lbrack {{- \frac{1}{2\sigma_{i}^{2}}}\left( {y_{i} - s_{j}^{0,k}} \right)^{2}} \right\rbrack}}}},{k = 1},\quad \ldots \quad,K} \\ {\cong {\frac{1}{\sigma_{i}^{2}}\left\lbrack {{y_{i}\left( s_{\min - {S^{0,k}\min}}^{1,k} \right)} - {0.5\left( s^{1,k_{\min^{2}{- S^{0,k_{\min^{2}}}}}} \right)}} \right\rbrack}} \end{matrix}$

[0096] where irrelevant terms and constants are dropped and s^(l,k) _(min) denotes the symbol closest to y_(i) that has 1 in the k-th bit position (and similarly for s^(0,k) _(min)). Thus, by means of this approximation (so called log-max approximation) the calculation of exponentials is avoided. However, as a consequence of using this approximation a fraction of dB can be lost in performance.

[0097] Consider now possible improvements of soft metric for the impulsive noise scenario. Let us assume that the noisy symbol sample is passed through a nonlinearity of the form (soft limiter or linear clipper). It is desired to construct a soft metric that performs approximately the same in AWGN as previously considered metrics, yet that will have smaller degradation in impulsive noise. That is, it has to have enough “softness” to maximize the performance in AWGN and to limit metric samples when impulsive noise is present, i.e. to prevent the excessive metric growth when large noise samples are present. Toward that goal consider the 8-ASK constellation and nonlinearities shown in FIG. 11. In FIG. 11, line 290 represents the output soft metric for bit A, line 292 represents the output soft metric for bit B, and line 294 represents the output soft metric for bit C. FIGS. 12 and 13 illustrate nonlinearities for 4-ASK and QPSK, respectively. In FIG. 12, line 296 represents the output soft metric for bit A, and line 298 represents the output soft metric for bit B. In FIG. 13, line 300 represents the output soft metric for bit A.

[0098] Based on the value of received noisy signal we construct soft metrics by processing the received samples through the different nonlinearities shown in FIGS. 11 through 13. The constructed soft bit values are further divided by the corresponding values of average noise power estimated for the symbol. In summary, the soft metric can be represented by: ${soft\_ out}_{i} = \frac{F\left( y_{i} \right)}{\sigma_{i}^{2}}$

[0099] where y represents the received noisy symbol, F(.) is the desired nonlinearity from FIGS. 11 through 13, and σ is the standard deviation of the noise.

[0100] This invention uses “Complementary Pattern-Mapped Convolutional Codes” (CPCC). These codes have the property that the original code can be segmented into multiple component codes, each of higher rate than the original code. The component codes are designed to perform well under certain interference conditions or fading in the channel. Furthermore, the code bits can be efficiently mapped onto bandwidth-efficient signals that carry more than one bit per dimension (QAM, for example).

[0101] While this invention has been described in terms of its preferred embodiments, it will be apparent to those skilled in the art that various changes can be made to the described embodiments without departing from the scope fo the invention as defined by the following claims.

1 118 1 32 DNA Artificial Sequence Description of Artificial Sequence Primer 1 ccttaattaa atgcacgaag cggagataaa ag 32 2 30 DNA Artificial Sequence Description of Artificial Sequence Primer 2 ccttaattaa gcataagctt gctcgagtct 30 3 31 DNA Artificial Sequence Description of Artificial Sequence Primer 3 ccttaattaa acgcaatggg aacatggagt g 31 4 34 DNA Artificial Sequence Description of Artificial Sequence Primer 4 ccttaattaa tcgcactacg gttattggta tcag 34 5 29 DNA Artificial Sequence Description of Artificial Sequence Primer 5 ccttaattaa tcaaagtacg ttcaggcgg 29 6 34 DNA Artificial Sequence Description of Artificial Sequence Primer 6 ccttaattaa ggcagacaac aacttggcaa agtc 34 7 31 DNA Artificial Sequence Description of Artificial Sequence Primer 7 ccttaattaa gaggtcgttg gttgagtttt c 31 8 29 DNA Artificial Sequence Description of Artificial Sequence Primer 8 ccttaattaa ttgataatga cgttgcggg 29 9 33 DNA Artificial Sequence Description of Artificial Sequence Primer 9 aggcgcgccg gagtccaaaa agaccaacct ctg 33 10 34 DNA Artificial Sequence Description of Artificial Sequence Primer 10 ccttaattaa tacgtggata ccttcaagca agtg 34 11 35 DNA Artificial Sequence Description of Artificial Sequence Primer 11 ccttaattaa gctcacgagt tttgggattt tcgag 35 12 35 DNA Artificial Sequence Description of Artificial Sequence Primer 12 gggtttaaac cgcagaggtt ggtctttttg gactc 35 13 10 DNA Artificial Sequence Description of Artificial Sequence Primer 13 gggtttaaac 10 14 9 DNA Artificial Sequence Description of Artificial Sequence Primer 14 aggcgcgcc 9 15 10 DNA Artificial Sequence Description of Artificial Sequence Primer 15 ccttaattaa 10 16 21 DNA Artificial Sequence Description of Artificial Sequence Primer 16 tcycaaacwg gtacwgcwga a 21 17 21 DNA Artificial Sequence Description of Artificial Sequence Primer 17 ggtttgggta aytcwactta t 21 18 18 DNA Artificial Sequence Description of Artificial Sequence Primer 18 cgttattatc atttcttc 18 19 20 DNA Artificial Sequence Description of Artificial Sequence Primer 19 gcmacaccrg tacctggacc 20 20 18 DNA Artificial Sequence Description of Artificial Sequence Primer 20 atcccaatcg taatcagc 18 21 18 DNA Artificial Sequence Description of Artificial Sequence Primer 21 acttgtcttc gtttagca 18 22 18 DNA Artificial Sequence Description of Artificial Sequence Primer 22 ctacgtctgt ggtgatgc 18 23 17 DNA Artificial Sequence Description of Artificial Sequence Primer 23 cgngayacna cngcngg 17 24 17 DNA Artificial Sequence Description of Artificial Sequence Primer 24 agrgayacna cngcngg 17 25 17 DNA Artificial Sequence Description of Artifiical Sequence Primer 25 agngcraayt gytgncc 17 26 18 DNA Artificial Sequence Description of Artificial Sequence Primer 26 yaangcraay tgytgncc 18 27 29 DNA Artificial Sequence Description of Artificial Sequence Primer 27 attcaacggt ggtccaagaa tctgtttgg 29 28 25 DNA Artificial Sequence Description of Artificial Sequence Primer 28 gagctatgtt gagaccacag tttgc 25 29 26 DNA Artificial Sequence Description of Artificial Sequence Primer 29 cttcagttaa agcaaattgt ttggcc 26 30 25 DNA Artificial Sequence Description of Artificial Sequence Primer 30 ctcgggaagc gcgccattgt gttgg 25 31 29 DNA Artificial Sequence Description of Artificial Sequence Primer 31 taatacgact cactataggg cgaattggc 29 32 21 DNA Artificial Sequence Description of Artificial Sequence Primer 32 tgrytcaaac catctytctg g 21 33 17 DNA Artificial Sequence Description of Artificial Sequence Primer 33 ggaccggcgt taaaggg 17 34 23 DNA Artificial Sequence Description of Artificial Sequence Primer 34 catagtcgwa tyatgcttag acc 23 35 17 DNA Artificial Sequence Description of Artificial Sequence Primer 35 ggaccaccat tgaatgg 17 36 540 DNA Candida tropicalis 36 atgattgaac aactcctaga atattggtat gtcgttgtgc cagtgttgta catcatcaaa 60 caactccttg catacacaaa gactcgcgtc ttgatgaaaa agttgggtgc tgctccagtc 120 acaaacaagt tgtacgacaa cgctttcggt atcgtcaatg gatggaaggc tctccagttc 180 aagaaagagg gcagggctca agagtacaac gattacaagt ttgaccactc caagaaccca 240 agcgtgggca cctacgtcag tattcttttc ggcaccagga tcgtcgtgac caaagatcca 300 gagaatatca aagctatttt ggcaacccag tttggtgatt tttctttggg caagaggcac 360 actcttttta agcctttgtt aggtgatggg atcttcacat tggacggcga aggctggaag 420 cacagcagag ccatgttgag accacagttt gccagagaac aagttgctca tgtgacgtcg 480 ttggaaccac acttccagtt gttgaagaag catattctta agcacaaggg tgaatacttt 540 37 25 DNA Artificial Sequence Description of Artificial Sequence Primer 37 ccgatgaagt tttcgacgag taccc 25 38 26 DNA Artificial Sequence Description of Artificial Sequence Primer 38 aaggctttaa cgtgtccaat ctggtc 26 39 27 DNA Artificial Sequence Description of Artificial Sequence Primer 39 attatcgcca catacttcac caaatgg 27 40 24 DNA Artificial Sequence Description of Artificial Sequence Primer 40 cgagatcgtg gatacgctgg agtg 24 41 25 DNA Artificial Sequence Description of Artificial Sequence Primer 41 gccactcggt aactttgtca gggac 25 42 26 DNA Artificial Sequence Description of Artificial Sequence Primer 42 cattgaactg agtagccaaa acagcc 26 43 27 DNA Artificial Sequence Description of Artificial Sequence Primer 43 cctacgtttg gtatcgctac tccgttg 27 44 22 DNA Artificial Sequence Description of Artificial Sequence Primer 44 tttccagcca gcaccgtcca ag 22 45 24 DNA Artificial Sequence Description of Artificial Sequence Primer 45 gcagagccga tctatgttgc gtcc 24 46 25 DNA Artificial Sequence Description of Artificial Sequence Primer 46 tcattgaatg cttccaggaa cctcg 25 47 20 DNA Artificial Sequence Description of Artificial Sequence Primer 47 aagagggcag ggctcaagag 20 48 21 DNA Artificial Sequence Description of Artificial Sequence Primer 48 tccatgtgaa gatcccatca c 21 49 20 DNA Artificial Sequence Description of Artificial Sequence Primer 49 cttgaaggcc gtgttgaacg 20 50 21 DNA Artificial Sequence Description of Artificial Sequence Primer 50 caggatttgt ctgagttgcc g 21 51 28 DNA Artificial Sequence Description of Artificial Sequence Primer 51 ccattgcctt gagatacgcc attggtag 28 52 26 DNA Artificial Sequence Description of Artificial Sequence Primer 52 agccttggtg tcgttctttt caacgg 26 53 26 DNA Artificial Sequence Description of Artificial Sequence Primer 53 ttgggtttgt ttgtttcctg tgtccg 26 54 27 DNA Artificial Sequence Description of Artificial Sequence Primer 54 cctttgacct tcaatctggc gtagacg 27 55 26 DNA Artificial Sequence Description of Artificial Sequence Primer 55 gtttgctgaa tacgctgaag gtgatg 26 56 27 DNA Artificial Sequence Description of Artificial Sequence Primer 56 tggagctgaa caactctctc gtctcgg 27 57 20 DNA Artificial Sequence Description of Artificial Sequence Primer 57 ttcctcaaca cggacagcgg 20 58 24 DNA Artificial Sequence Description of Artificial Sequence Primer 58 agtcaaccag gtgtggaact cgtc 24 59 49 DNA Artificial Sequence Description of Artificial Sequence Primer 59 ggatcctaat acgactcact atagggagga agagggcagg gctcaagag 49 60 42 DNA Artificial Sequence Description of Artificial Sequence Primer 60 tccatgtgaa gatcccatca cgagtgtgcc tcttgcccaa ag 42 61 54 DNA Artificial Sequence Description of Artificial Sequence Primer 61 ggatcctaat acgactcact atagggaggc cgatgaagtt ttcgacgagt accc 54 62 52 DNA Artificial Sequence Description of Artificial Sequence Primer 62 aaggctttaa cgtgtccaat ctggtcaaca tagctctgga gtgcttccaa cc 52 63 56 DNA Artificial Sequence Description of Artificial Sequence Primer 63 ggatcctaat acgactcact atagggagga ttatcgccac atacttcacc aaatgg 56 64 52 DNA Artificial Sequence Description of Artificial Sequence Primer 64 cgagatcgtg gatacgctgg agtgcgtcgc tcttcttctt caacaattca ag 52 65 49 DNA Artificial Sequence Description of Artificial Sequence Primer 65 cattgaactg agtagccaaa acagcccatg gtttcaatca atgggaggc 49 66 54 DNA Artificial Sequence Description of Artificial Sequence Primer 66 ggatcctaat acgactcact atagggaggg ccactcggta actttgtcag ggac 54 67 56 DNA Artificial Sequence Description of Artificial Sequence Primer 67 ggatcctaat acgactcact atagggaggc ctacgtttgg tatcgctact ccgttg 56 68 48 DNA Artificial Sequence Description of Artificial Sequence Primer 68 tttccagcca gcaccgtcca agcaacaagg agtacaagaa atcgtgtc 48 69 53 DNA Artificial Sequence Description of Artificial Sequence Primer 69 ggatcctaat acgactcact atagggaggg cagagccgat ctatgttgcg tcc 53 70 45 DNA Artificial Sequence Description of Artificial Sequence Primer 70 tcattgaatg cttccaggaa cctcgccaca tccatcgaga accgg 45 71 49 DNA Artificial Sequence Description of Artificial Sequence Primer 71 ggatcctaat acgactcact atagggaggc ttgaaggccg tgttgaacg 49 72 46 DNA Artificial Sequence Description of Artificial Sequence Primer 72 caggatttgt ctgagttgcc gcctgatcaa gataggatcc ttgccg 46 73 56 DNA Artificial Sequence Description of Artificial Sequence Primer 73 ggatcctaat acgactcact atagggaggg gtttgctgaa tacgctgaag gtgatg 56 74 52 DNA Artificial Sequence Description of Artificial Sequence Primer 74 tggagctgaa caactctctc gtctcgggtg gtcgaatgga cccttggtca ag 52 75 49 DNA Artificial Sequence Description of Artificial Sequence Primer 75 ggatcctaat acgactcact atagggaggt tcctcaacac ggacagcgg 49 76 49 DNA Artificial Sequence Description of Artificial Sequence Primer 76 agtcaaccag gtgtggaact cgtcggtggc aacaatgaaa aacaccaag 49 77 57 DNA Artificial Sequence Description of Artificial Sequence Primer 77 ggatcctaat acgactcact atagggaggc cattgccttg agatacgcca ttggtag 57 78 53 DNA Artificial Sequence Description of Artificial Sequence Primer 78 agccttggtg tcgttctttt caacggaagg tggtctcgat ggtgtgttca acc 53 79 55 DNA Artificial Sequence Description of Artificial Sequence Primer 79 ggatcctaat acgactcact atagggaggt tgggtttgtt tgtttcctgt gtccg 55 80 50 DNA Artificial Sequence Description of Artificial Sequence Primer 80 cctttgacct tcaatctggc gtagacgcag caccaccgat ccaccacttg 50 81 4206 DNA Candida tropicalis 81 catcaagatc atctatgggg ataattacga cagcaacatt gcagaaagag cgttggtcac 60 aatcgaaaga gcctatggcg ttgccgtcgt tgaggcaaat gacagcacca acaataacga 120 tggtcccagt gaagagcctt cagaacagtc cattgttgac gcttaaggca cggataatta 180 cgtggggcaa aggaacgcgg aattagttat ggggggatca aaagcggaag atttgtgttg 240 cttgtgggtt ttttccttta tttttcatat gatttctttg cgcaagtaac atgtgccaat 300 ttagtttgtg attagcgtgc cccacaattg gcatcgtgga cgggcgtgtt ttgtcatacc 360 ccaagtctta actagctcca cagtctcgac ggtgtctcga cgatgtcttc ttccacccct 420 cccatgaatc attcaaagtt gttgggggat ctccaccaag ggcaccggag ttaatgctta 480 tgtttctccc actttggttg tgattggggt agtctagtga gttggagatt ttcttttttt 540 cgcaggtgtc tccgatatcg aaatttgatg aatatagaga gaagccagat cagcacagta 600 gattgccttt gtagttagag atgttgaaca gcaactagtt gaattacacg ccaccacttg 660 acagcaagtg cagtgagctg taaacgatgc agccagagtg tcaccaccaa ctgacgttgg 720 gtggagttgt tgttgttgtt gttggcaggg ccatattgct aaacgaagac aagtagcaca 780 aaacccaagc ttaagaacaa aaataaaaaa aattcatacg acaattccaa agccattgat 840 ttacataatc aacagtaaga cagaaaaaac tttcaacatt tcaaagttcc ctttttccta 900 ttacttcttt tttttcttct ttccttcttt ccttctgttt ttcttacttt atcagtcttt 960 tacttgtttt tgcaattcct catcctcctc ctactcctcc tcaccatggc tttagacaag 1020 ttagatttgt atgtcatcat aacattggtg gtcgctgtag ccgcctattt tgctaagaac 1080 cagttccttg atcagcccca ggacaccggg ttcctcaaca cggacagcgg aagcaactcc 1140 agagacgtct tgctgacatt gaagaagaat aataaaaaca cgttgttgtt gtttgggtcc 1200 cagacgggta cggcagaaga ttacgccaac aaattgtcca gagaattgca ctccagattt 1260 ggcttgaaaa cgatggttgc agatttcgct gattacgatt gggataactt cggagatatc 1320 accgaagaca tcttggtgtt tttcattgtt gccacctatg gtgagggtga acctaccgat 1380 aatgccgacg agttccacac ctggttgact gaagaagctg acactttgag taccttgaaa 1440 tacaccgtgt tcgggttggg taactccacg tacgagttct tcaatgccat tggtagaaag 1500 tttgacagat tgttgagcga gaaaggtggt gacaggtttg ctgaatacgc tgaaggtgat 1560 gacggtactg gcaccttgga cgaagatttc atggcctgga aggacaatgt ctttgacgcc 1620 ttgaagaatg atttgaactt tgaagaaaag gaattgaagt acgaaccaaa cgtgaaattg 1680 actgagagag acgacttgtc tgctgctgac tcccaagttt ccttgggtga gccaaacaag 1740 aagtacatca actccgaggg catcgacttg accaagggtc cattcgacca cacccaccca 1800 tacttggcca gaatcaccga gacgagagag ttgttcagct ccaaggacag acactgtatc 1860 cacgttgaat ttgacatttc tgaatcgaac ttgaaataca ccaccggtga ccatctagct 1920 atctggccat ccaactccga cgaaaacatt aagcaatttg ccaagtgttt cggattggaa 1980 gataaactcg acactgttat tgaattgaag gcgttggact ccacttacac catcccattc 2040 ccaaccccaa ttacctacgg tgctgtcatt agacaccatt tagaaatctc cggtccagtc 2100 tcgagacaat tctttttgtc aattgctggg tttgctcctg atgaagaaac aaagaaggct 2160 tttaccagac ttggtggtga caagcaagaa ttcgccgcca aggtcacccg cagaaagttc 2220 aacattgccg atgccttgtt atattcctcc aacaacgctc catggtccga tgttcctttt 2280 gaattcctta ttgaaaacgt tccacacttg actccacgtt actactccat ttcgtcttcg 2340 tcattgagtg aaaagcaact catcaacgtt actgcagttg ttgaagccga agaagaagct 2400 gatggcagac cagtcactgg tgttgtcacc aacttgttga agaacgttga aattgtgcaa 2460 aacaagactg gcgaaaagcc acttgtccac tacgatttga gcggcccaag aggcaagttc 2520 aacaagttca agttgccagt gcatgtgaga agatccaact ttaagttgcc aaagaactcc 2580 accaccccag ttatcttgat tggtccaggt actggtgttg ccccattgag aggttttgtc 2640 agagaaagag ttcaacaagt caagaatggt gtcaatgttg gcaagacttt gttgttttat 2700 ggttgcagaa actccaacga ggactttttg tacaagcaag aatgggccga gtacgcttct 2760 gttttgggtg aaaactttga gatgttcaat gccttctcca gacaagaccc atccaagaag 2820 gtttacgtcc aggataagat tttagaaaac agccaacttg tgcacgagtt gttgactgaa 2880 ggtgccatta tctacgtctg tggtgatgcc agtagaatgg ctagagacgt gcagaccaca 2940 atttccaaga ttgttgctaa aagcagagaa attagtgaag acaaggctgc tgaattggtc 3000 aagtcctgga aggtccaaaa tagataccaa gaagatgttt ggtagactca aacgaatctc 3060 tctttctccc aacgcattta tgaatcttta ttctcattga agctttacat atgttctaca 3120 ctttattttt tttttttttt ttattattat attacgaaac ataggtcaac tatatatact 3180 tgattaaatg ttatagaaac aataactatt atctactcgt ctacttcttt ggcattgaca 3240 tcaacattac cgttcccatt accgttgccg ttggcaatgc cgggatattt agtacagtat 3300 ctccaatccg gatttgagct attgtagatc agctgcaagt cattctccac cttcaaccag 3360 tacttatact tcatctttga cttcaagtcc aagtcataaa tattacaagt tagcaagaac 3420 ttctggccat ccacgatata gacgttattc acgttattat gcgacgtatg gatgtggtta 3480 tccttattga acttctcaaa cttcaaaaac aaccccacgt cccgcaacgt cattatcaac 3540 gacaagttct ggctcacgtc gtcggagctc gtcaagttct caattagatc gttcttgtta 3600 ttgatcttct ggtactttct caattgctgg aacacattgt cctcgttgtt caaatagatc 3660 ttgaacaact ttttcaacgg gatcaacttc tcaatctggg ccaagatctc cgccgggatc 3720 ttcagaaaca agtcctgcaa cccctggtcg atggtctccg ggtacaacaa gtccaagggg 3780 cagaagtgtc taggcacgtg tttcaactgg ttcaacgaac atgttcgaca gtagttcgag 3840 ttatagttat cgtacaacca ttttggtttg atttcgaaaa tgacggagct gatgccatca 3900 ttctcctggt tcctctcata gtacaactgg cacttcttcg agaggctcaa ttcctcgtag 3960 ttcccgtcca agatattcgg caacaagagc ccgtaccgct cacggagcat caagtcgtgg 4020 ccctggttgt tcaacttgtt gatgaagtcc gaggtcaaga caatcaactg gatgtcgatg 4080 atctggtgcg ggaacaagtt cttgcatttt agctcgatga agtcgtacaa ctcacacgtc 4140 gagatatact cctgttcctc cttcaagagc cggatccgca agagcttgtg cttcaagtag 4200 tcgttg 4206 82 4145 DNA Candida tropicalis 82 tatatgatat atgatatatc ttcctgtgta attattattc gtattcgtta atacttacta 60 catttttttt tctttattta tgaagaaaag gagagttcgt aagttgagtt gagtagaata 120 ggctgttgtg catacgggga gcagaggaga gtatccgacg aggaggaact gggtgaaatt 180 tcatctatgc tgttgcgtcc tgtactgtac tgtaaatctt agatttccta gaggttgttc 240 tagcaaataa agtgtttcaa gatacaattt tacaggcaag ggtaaaggat caactgatta 300 gcggaagatt ggtgttgcct gtggggttct tttatttttc atatgatttc tttgcgcgag 360 taacatgtgc caatctagtt tatgattagc gtacctccac aattggcatc ttggacgggc 420 gtgttttgtc ttaccccaag ccttatttag ttccacagtc tcgacggtgt ctcgccgatg 480 tcttctccca cccctcgcag gaatcattcg aagttgttgg gggatctcct ccgcagttta 540 tgttcatgtc tttcccactt tggttgtgat tggggtagcg tagtgagttg gtgattttct 600 tttttcgcag gtgtctccga tatcgaagtt tgatgaatat aggagccaga tcagcatggt 660 atattgcctt tgtagataga gatgttgaac aacaactagc tgaattacac accaccgcta 720 aacgatgcgc acagggtgtc accgccaact gacgttgggt ggagttgttg ttggcagggc 780 catattgcta aacgaagaga agtagcacaa aacccaaggt taagaacaat taaaaaaatt 840 catacgacaa ttccacagcc atttacataa tcaacagcga caaatgagac agaaaaaact 900 ttcaacattt caaagttccc tttttcctat tacttctttt tttctttcct tcctttcatt 960 tcctttcctt ctgcttttat tactttacca gtcttttgct tgtttttgca attcctcatc 1020 ctcctcctca ccatggcttt agacaagtta gatttgtatg tcatcataac attggtggtc 1080 gctgtggccg cctattttgc taagaaccag ttccttgatc agccccagga caccgggttc 1140 ctcaacacgg acagcggaag caactccaga gacgtcttgc tgacattgaa gaagaataat 1200 aaaaacacgt tgttgttgtt tgggtcccag accggtacgg cagaagatta cgccaacaaa 1260 ttgtcaagag aattgcactc cagatttggc ttgaaaacca tggttgcaga tttcgctgat 1320 tacgattggg ataacttcgg agatatcacc gaagatatct tggtgttttt catcgttgcc 1380 acctacggtg agggtgaacc taccgacaat gccgacgagt tccacacctg gttgactgaa 1440 gaagctgaca ctttgagtac tttgagatat accgtgttcg ggttgggtaa ctccacctac 1500 gagttcttca atgctattgg tagaaagttt gacagattgt tgagtgagaa aggtggtgac 1560 agatttgctg aatatgctga aggtgacgac ggcactggca ccttggacga agatttcatg 1620 gcctggaagg ataatgtctt tgacgccttg aagaatgact tgaactttga agaaaaggaa 1680 ttgaagtacg aaccaaacgt gaaattgact gagagagatg acttgtctgc tgccgactcc 1740 caagtttcct tgggtgagcc aaacaagaag tacatcaact ccgagggcat cgacttgacc 1800 aagggtccat tcgaccacac ccacccatac ttggccagga tcaccgagac cagagagttg 1860 ttcagctcca aggaaagaca ctgtattcac gttgaatttg acatttctga atcgaacttg 1920 aaatacacca ccggtgacca tctagccatc tggccatcca actccgacga aaacatcaag 1980 caatttgcca agtgtttcgg attggaagat aaactcgaca ctgttattga attgaaggca 2040 ttggactcca cttacaccat tccattccca actccaatta cttacggtgc tgtcattaga 2100 caccatttag aaatctccgg tccagtctcg agacaattct ttttgtcgat tgctgggttt 2160 gctcctgatg aagaaacaaa gaagactttc accagacttg gtggtgacaa acaagaattc 2220 gccaccaagg ttacccgcag aaagttcaac attgccgatg ccttgttata ttcctccaac 2280 aacactccat ggtccgatgt tccttttgag ttccttattg aaaacatcca acacttgact 2340 ccacgttact actccatttc ttcttcgtcg ttgagtgaaa aacaactcat caatgttact 2400 gcagtcgttg aggccgaaga agaagccgat ggcagaccag tcactggtgt tgttaccaac 2460 ttgttgaaga acattgaaat tgcgcaaaac aagactggcg aaaagccact tgttcactac 2520 gatttgagcg gcccaagagg caagttcaac aagttcaagt tgccagtgca cgtgagaaga 2580 tccaacttta agttgccaaa gaactccacc accccagtta tcttgattgg tccaggtact 2640 ggtgttgccc cattgagagg tttcgttaga gaaagagttc aacaagtcaa gaatggtgtc 2700 aatgttggca agactttgtt gttttatggt tgcagaaact ccaacgagga ctttttgtac 2760 aagcaagaat gggccgagta cgcttctgtt ttgggtgaaa actttgagat gttcaatgcc 2820 ttctctagac aagacccatc caagaaggtt tacgtccagg ataagatttt agaaaacagc 2880 caacttgtgc acgaattgtt gaccgaaggt gccattatct acgtctgtgg tgacgccagt 2940 agaatggcca gagacgtcca gaccacgatc tccaagattg ttgccaaaag cagagaaatc 3000 agtgaagaca aggccgctga attggtcaag tcctggaaag tccaaaatag ataccaagaa 3060 gatgtttggt agactcaaac gaatctctct ttctcccaac gcatttatga atattctcat 3120 tgaagtttta catatgttct atatttcatt ttttttttat tatattacga aacataggtc 3180 aactatatat acttgattaa atgttataga aacaataatt attatctact cgtctacttc 3240 tttggcattg gcattggcat tggcattggc attgccgttg ccgttggtaa tgccgggata 3300 tttagtacag tatctccaat ccggatttga gctattgtaa atcagctgca agtcattctc 3360 caccttcaac cagtacttat acttcatctt tgacttcaag tccaagtcat aaatattaca 3420 agttagcaag aacttctggc catccacaat atagacgtta ttcacgttat tatgcgacgt 3480 atggatatgg ttatccttat tgaacttctc aaacttcaaa aacaacccca cgtcccgcaa 3540 cgtcattatc aacgacaagt tctgactcac gtcgtcggag ctcgtcaagt tctcaattag 3600 atcgttcttg ttattgatct tctggtactt tctcaactgc tggaacacat tgtcctcgtt 3660 gttcaaatag atcttgaaca acttcttcaa gggaatcaac ttttcgatct gggccaagat 3720 ttccgccggg atcttcagaa acaagtcctg caacccctgg tcgatggtct cggggtacaa 3780 caagtctaag gggcagaagt gtctaggcac gtgtttcaac tggttcaagg aacatgttcg 3840 acagtagttc gagttatagt tatcgtacaa ccactttggc ttgatttcga aaatgacgga 3900 gctgatccca tcattctcct ggttcctttc atagtacaac tggcatttct tcgagagact 3960 caactcctcg tagttcccgt ccaagatatt cggcaacaag agcccgtagc gctcacggag 4020 catcaagtcg tggccctggt tgttcaactt gttgatgaag tccgatgtca agacaatcaa 4080 ctggatgtcg atgatctggt gcggaaacaa gttcttgcac tttagctcga tgaagtcgta 4140 caact 4145 83 679 PRT CANDIDATROPICALIS 83 Met Ala Leu Asp Lys Leu Asp Leu Tyr Val Ile Ile Thr Leu Val Val 1 5 10 15 Ala Val Ala Ala Tyr Phe Ala Lys Asn Gln Phe Leu Asp Gln Pro Gln 20 25 30 Asp Thr Gly Phe Leu Asn Thr Asp Ser Gly Ser Asn Ser Arg Asp Val 35 40 45 Leu Leu Thr Leu Lys Lys Asn Asn Lys Asn Thr Leu Leu Leu Phe Gly 50 55 60 Ser Gln Thr Gly Thr Ala Glu Asp Tyr Ala Asn Lys Leu Ser Arg Glu 65 70 75 80 Leu His Ser Arg Phe Gly Leu Lys Thr Met Val Ala Asp Phe Ala Asp 85 90 95 Tyr Asp Trp Asp Asn Phe Gly Asp Ile Thr Glu Asp Ile Leu Val Phe 100 105 110 Phe Ile Val Ala Thr Tyr Gly Glu Gly Glu Pro Thr Asp Asn Ala Asp 115 120 125 Glu Phe His Thr Trp Leu Thr Glu Glu Ala Asp Thr Leu Ser Thr Leu 130 135 140 Lys Tyr Thr Val Phe Gly Leu Gly Asn Ser Thr Tyr Glu Phe Phe Asn 145 150 155 160 Ala Ile Gly Arg Lys Phe Asp Arg Leu Leu Ser Glu Lys Gly Gly Asp 165 170 175 Arg Phe Ala Glu Tyr Ala Glu Gly Asp Asp Gly Thr Gly Thr Leu Asp 180 185 190 Glu Asp Phe Met Ala Trp Lys Asp Asn Val Phe Asp Ala Leu Lys Asn 195 200 205 Asp Leu Asn Phe Glu Glu Lys Glu Leu Lys Tyr Glu Pro Asn Val Lys 210 215 220 Leu Thr Glu Arg Asp Asp Leu Ser Ala Ala Asp Ser Gln Val Ser Leu 225 230 235 240 Gly Glu Pro Asn Lys Lys Tyr Ile Asn Ser Glu Gly Ile Asp Leu Thr 245 250 255 Lys Gly Pro Phe Asp His Thr His Pro Tyr Leu Ala Arg Ile Thr Glu 260 265 270 Thr Arg Glu Leu Phe Ser Ser Lys Asp Arg His Cys Ile His Val Glu 275 280 285 Phe Asp Ile Ser Glu Ser Asn Leu Lys Tyr Thr Thr Gly Asp His Leu 290 295 300 Ala Ile Trp Pro Ser Asn Ser Asp Glu Asn Ile Lys Gln Phe Ala Lys 305 310 315 320 Cys Phe Gly Leu Glu Asp Lys Leu Asp Thr Val Ile Glu Leu Lys Ala 325 330 335 Leu Asp Ser Thr Tyr Thr Ile Pro Phe Pro Thr Pro Ile Thr Tyr Gly 340 345 350 Ala Val Ile Arg His His Leu Glu Ile Ser Gly Pro Val Ser Arg Gln 355 360 365 Phe Phe Leu Ser Ile Ala Gly Phe Ala Pro Asp Glu Glu Thr Lys Lys 370 375 380 Ala Phe Thr Arg Leu Gly Gly Asp Lys Gln Glu Phe Ala Ala Lys Val 385 390 395 400 Thr Arg Arg Lys Phe Asn Ile Ala Asp Ala Leu Leu Tyr Ser Ser Asn 405 410 415 Asn Ala Pro Trp Ser Asp Val Pro Phe Glu Phe Leu Ile Glu Asn Val 420 425 430 Pro His Leu Thr Pro Arg Tyr Tyr Ser Ile Ser Ser Ser Ser Leu Ser 435 440 445 Glu Lys Gln Leu Ile Asn Val Thr Ala Val Val Glu Ala Glu Glu Glu 450 455 460 Ala Asp Gly Arg Pro Val Thr Gly Val Val Thr Asn Leu Leu Lys Asn 465 470 475 480 Val Glu Ile Val Gln Asn Lys Thr Gly Glu Lys Pro Leu Val His Tyr 485 490 495 Asp Leu Ser Gly Pro Arg Gly Lys Phe Asn Lys Phe Lys Leu Pro Val 500 505 510 His Val Arg Arg Ser Asn Phe Lys Leu Pro Lys Asn Ser Thr Thr Pro 515 520 525 Val Ile Leu Ile Gly Pro Gly Thr Gly Val Ala Pro Leu Arg Gly Phe 530 535 540 Val Arg Glu Arg Val Gln Gln Val Lys Asn Gly Val Asn Val Gly Lys 545 550 555 560 Thr Leu Leu Phe Tyr Gly Cys Arg Asn Ser Asn Glu Asp Phe Leu Tyr 565 570 575 Lys Gln Glu Trp Ala Glu Tyr Ala Ser Val Leu Gly Glu Asn Phe Glu 580 585 590 Met Phe Asn Ala Phe Ser Arg Gln Asp Pro Ser Lys Lys Val Tyr Val 595 600 605 Gln Asp Lys Ile Leu Glu Asn Ser Gln Leu Val His Glu Leu Leu Thr 610 615 620 Glu Gly Ala Ile Ile Tyr Val Cys Gly Asp Ala Ser Arg Met Ala Arg 625 630 635 640 Asp Val Gln Thr Thr Ile Ser Lys Ile Val Ala Lys Ser Arg Glu Ile 645 650 655 Ser Glu Asp Lys Ala Ala Glu Leu Val Lys Ser Trp Lys Val Gln Asn 660 665 670 Arg Tyr Gln Glu Asp Val Trp 675 84 679 PRT CANDIDATROPICALIS 84 Met Ala Leu Asp Lys Leu Asp Leu Tyr Val Ile Ile Thr Leu Val Val 1 5 10 15 Ala Val Ala Ala Tyr Phe Ala Lys Asn Gln Phe Leu Asp Gln Pro Gln 20 25 30 Asp Thr Gly Phe Leu Asn Thr Asp Ser Gly Ser Asn Ser Arg Asp Val 35 40 45 Leu Leu Thr Leu Lys Lys Asn Asn Lys Asn Thr Leu Leu Leu Phe Gly 50 55 60 Ser Gln Thr Gly Thr Ala Glu Asp Tyr Ala Asn Lys Leu Ser Arg Glu 65 70 75 80 Leu His Ser Arg Phe Gly Leu Lys Thr Met Val Ala Asp Phe Ala Asp 85 90 95 Tyr Asp Trp Asp Asn Phe Gly Asp Ile Thr Glu Asp Ile Leu Val Phe 100 105 110 Phe Ile Val Ala Thr Tyr Gly Glu Gly Glu Pro Thr Asp Asn Ala Asp 115 120 125 Glu Phe His Thr Trp Leu Thr Glu Glu Ala Asp Thr Leu Ser Thr Leu 130 135 140 Arg Tyr Thr Val Phe Gly Leu Gly Asn Ser Thr Tyr Glu Phe Phe Asn 145 150 155 160 Ala Ile Gly Arg Lys Phe Asp Arg Leu Leu Ser Glu Lys Gly Gly Asp 165 170 175 Arg Phe Ala Glu Tyr Ala Glu Gly Asp Asp Gly Thr Gly Thr Leu Asp 180 185 190 Glu Asp Phe Met Ala Trp Lys Asp Asn Val Phe Asp Ala Leu Lys Asn 195 200 205 Asp Leu Asn Phe Glu Glu Lys Glu Leu Lys Tyr Glu Pro Asn Val Lys 210 215 220 Leu Thr Glu Arg Asp Asp Leu Ser Ala Ala Asp Ser Gln Val Ser Leu 225 230 235 240 Gly Glu Pro Asn Lys Lys Tyr Ile Asn Ser Glu Gly Ile Asp Leu Thr 245 250 255 Lys Gly Pro Phe Asp His Thr His Pro Tyr Leu Ala Arg Ile Thr Glu 260 265 270 Thr Arg Glu Leu Phe Ser Ser Lys Glu Arg His Cys Ile His Val Glu 275 280 285 Phe Asp Ile Ser Glu Ser Asn Leu Lys Tyr Thr Thr Gly Asp His Leu 290 295 300 Ala Ile Trp Pro Ser Asn Ser Asp Glu Asn Ile Lys Gln Phe Ala Lys 305 310 315 320 Cys Phe Gly Leu Glu Asp Lys Leu Asp Thr Val Ile Glu Leu Lys Ala 325 330 335 Leu Asp Ser Thr Tyr Thr Ile Pro Phe Pro Thr Pro Ile Thr Tyr Gly 340 345 350 Ala Val Ile Arg His His Leu Glu Ile Ser Gly Pro Val Ser Arg Gln 355 360 365 Phe Phe Leu Ser Ile Ala Gly Phe Ala Pro Asp Glu Glu Thr Lys Lys 370 375 380 Thr Phe Thr Arg Leu Gly Gly Asp Lys Gln Glu Phe Ala Thr Lys Val 385 390 395 400 Thr Arg Arg Lys Phe Asn Ile Ala Asp Ala Leu Leu Tyr Ser Ser Asn 405 410 415 Asn Thr Pro Trp Ser Asp Val Pro Phe Glu Phe Leu Ile Glu Asn Ile 420 425 430 Gln His Leu Thr Pro Arg Tyr Tyr Ser Ile Ser Ser Ser Ser Leu Ser 435 440 445 Glu Lys Gln Leu Ile Asn Val Thr Ala Val Val Glu Ala Glu Glu Glu 450 455 460 Ala Asp Gly Arg Pro Val Thr Gly Val Val Thr Asn Leu Leu Lys Asn 465 470 475 480 Ile Glu Ile Ala Gln Asn Lys Thr Gly Glu Lys Pro Leu Val His Tyr 485 490 495 Asp Leu Ser Gly Pro Arg Gly Lys Phe Asn Lys Phe Lys Leu Pro Val 500 505 510 His Val Arg Arg Ser Asn Phe Lys Leu Pro Lys Asn Ser Thr Thr Pro 515 520 525 Val Ile Leu Ile Gly Pro Gly Thr Gly Val Ala Pro Leu Arg Gly Phe 530 535 540 Val Arg Glu Arg Val Gln Gln Val Lys Asn Gly Val Asn Val Gly Lys 545 550 555 560 Thr Leu Leu Phe Tyr Gly Cys Arg Asn Ser Asn Glu Asp Phe Leu Tyr 565 570 575 Lys Gln Glu Trp Ala Glu Tyr Ala Ser Val Leu Gly Glu Asn Phe Glu 580 585 590 Met Phe Asn Ala Phe Ser Arg Gln Asp Pro Ser Lys Lys Val Tyr Val 595 600 605 Gln Asp Lys Ile Leu Glu Asn Ser Gln Leu Val His Glu Leu Leu Thr 610 615 620 Glu Gly Ala Ile Ile Tyr Val Cys Gly Asp Ala Ser Arg Met Ala Arg 625 630 635 640 Asp Val Gln Thr Thr Ile Ser Lys Ile Val Ala Lys Ser Arg Glu Ile 645 650 655 Ser Glu Asp Lys Ala Ala Glu Leu Val Lys Ser Trp Lys Val Gln Asn 660 665 670 Arg Tyr Gln Glu Asp Val Trp 675 85 4115 DNA Candida tropicalis 85 catatgcgct aatcttcttt ttctttttat cacaggagaa actatcccac ccccacttcg 60 aaacacaatg acaactcctg cgtaacttgc aaattcttgt ctgactaatt gaaaactccg 120 gacgagtcag acctccagtc aaacggacag acagacaaac acttggtgcg atgttcatac 180 ctacagacat gtcaacgggt gttagacgac ggtttcttgc aaagacaggt gttggcatct 240 cgtacgatgg caactgcagg aggtgtcgac ttctccttta ggcaatagaa aaagactaag 300 agaacagcgt ttttacaggt tgcattggtt aatgtagtat ttttttagtc ccagcattct 360 gtgggttgct ctgggtttct agaataggaa atcacaggag aatgcaaatt cagatggaag 420 aacaaagaga taaaaaacaa aaaaaaactg agttttgcac caatagaatg tttgatgata 480 tcatccactc gctaaacgaa tcatgtgggt gatcttctct ttagttttgg tctatcataa 540 aacacatgaa agtgaaatcc aaatacacta cactccgggt attgtccttc gttttacaga 600 tgtctcattg tcttactttt gaggtcatag gagttgcctg tgagagatca cagagattat 660 cacactcaca tttatcgtag tttcctatct catgctgtgt gtctctggtt ggttcatgag 720 tttggattgt tgtacattaa aggaatcgct ggaaagcaaa gctaactaaa ttttctttgt 780 cacaggtaca ctaacctgta aaacttcact gccacgccag tctttcctga ttgggcaagt 840 gcacaaacta caacctgcaa aacagcactc cgcttgtcac aggttgtctc ctctcaacca 900 acaaaaaaat aagattaaac tttctttgct catgcatcaa tcggagttat ctctgaaaga 960 gttgcctttg tgtaatgtgt gccaaactca aactgcaaaa ctaaccacag aatgatttcc 1020 ctcacaatta tataaactca cccacatttc cacagaccgt aatttcatgt ctcactttct 1080 cttttgctct tcttttactt agtcaggttt gataacttcc ttttttatta ccctatctta 1140 tttatttatt tattcattta taccaaccaa ccaaccatgg ccacacaaga aatcatcgat 1200 tctgtacttc cgtacttgac caaatggtac actgtgatta ctgcagcagt attagtcttc 1260 cttatctcca caaacatcaa gaactacgtc aaggcaaaga aattgaaatg tgtcgatcca 1320 ccatacttga aggatgccgg tctcactggt attctgtctt tgatcgccgc catcaaggcc 1380 aagaacgacg gtagattggc taactttgcc gatgaagttt tcgacgagta cccaaaccac 1440 accttctact tgtctgttgc cggtgctttg aagattgtca tgactgttga cccagaaaac 1500 atcaaggctg tcttggccac ccaattcact gacttctcct tgggtaccag acacgcccac 1560 tttgctcctt tgttgggtga cggtatcttc accttggacg gagaaggttg gaagcactcc 1620 agagctatgt tgagaccaca gtttgctaga gaccagattg gacacgttaa agccttggaa 1680 ccacacatcc aaatcatggc taagcagatc aagttgaacc agggaaagac tttcgatatc 1740 caagaattgt tctttagatt taccgtcgac accgctactg agttcttgtt tggtgaatcc 1800 gttcactcct tgtacgatga aaaattgggc atcccaactc caaacgaaat cccaggaaga 1860 gaaaactttg ccgctgcttt caacgtttcc caacactact tggccaccag aagttactcc 1920 cagacttttt actttttgac caaccctaag gaattcagag actgtaacgc caaggtccac 1980 cacttggcca agtactttgt caacaaggcc ttgaacttta ctcctgaaga actcgaagag 2040 aaatccaagt ccggttacgt tttcttgtac gaattggtta agcaaaccag agatccaaag 2100 gtcttgcaag atcaattgtt gaacattatg gttgccggaa gagacaccac tgccggtttg 2160 ttgtcctttg ctttgtttga attggctaga cacccagaga tgtggtccaa gttgagagaa 2220 gaaatcgaag ttaactttgg tgttggtgaa gactcccgcg ttgaagaaat taccttcgaa 2280 gccttgaaga gatgtgaata cttgaaggct atccttaacg aaaccttgcg tatgtaccca 2340 tctgttcctg tcaactttag aaccgccacc agagacacca ctttgccaag aggtggtggt 2400 gctaacggta ccgacccaat ctacattcct aaaggctcca ctgttgctta cgttgtctac 2460 aagacccacc gtttggaaga atactacggt aaggacgcta acgacttcag accagaaaga 2520 tggtttgaac catctactaa gaagttgggc tgggcttatg ttccattcaa cggtggtcca 2580 agagtctgct tgggtcaaca attcgccttg actgaagctt cttatgtgat cactagattg 2640 gcccagatgt ttgaaactgt ctcatctgat ccaggtctcg aataccctcc accaaagtgt 2700 attcacttga ccatgagtca caacgatggt gtctttgtca agatgtaaag tagtcgatgc 2760 tgggtattcg attacatgtg tataggaaga ttttggtttt ttattcgttc ttttttttaa 2820 tttttgttaa attagtttag agatttcatt aatacataga tgggtgctat ttccgaaact 2880 ttacttctat cccctgtatc ccttattatc cctctcagtc acatgattgc tgtaattgtc 2940 gtgcaggaca caaactccct aacggactta aaccataaac aagctcagaa ccataagccg 3000 acatcactcc ttcttctctc ttctccaacc aatagcatgg acagacccac cctcctatcc 3060 gaatcgaaga cccttattga ctccataccc acctggaagc ccctcaagcc acacacgtca 3120 tccagcccac ccatcaccac atccctctac tcgacaacgt ccaaagacgg cgagttctgg 3180 tgtgcccgga aatcagccat cccggccaca tacaagcagc cgttgattgc gtgcatactc 3240 ggcgagccca caatgggagc cacgcattcg gaccatgaag caaagtacat tcacgagatc 3300 acgggtgttt cagtgtcgca gattgagaag ttcgacgatg gatggaagta cgatctcgtt 3360 gcggattacg acttcggtgg gttgttatct aaacgaagat tctatgagac gcagcatgtg 3420 tttcggttcg aggattgtgc gtacgtcatg agtgtgcctt ttgatggacc caaggaggaa 3480 ggttacgtgg ttgggacgta cagatccatt gaaaggttga gctggggtaa agacggggac 3540 gtggagtgga ccatggcgac gacgtcggat cctggtgggt ttatcccgca atggataact 3600 cgattgagca tccctggagc aatcgcaaaa gatgtgccta gtgtattaaa ctacatacag 3660 aaataaaaac gtgtcttgat tcattggttt ggttcttgtt gggttccgag ccaatatttc 3720 acatcatctc ctaaattctc caagaatccc aacgtagcgt agtccagcac gccctctgag 3780 atcttattta atatcgactt ctcaaccacc ggtggaatcc cgttcagacc attgttacct 3840 gtagtgtgtt tgctcttgtt cttgatgaca atgatgtatt tgtcacgata cctgaaataa 3900 taaaacatcc agtcattgag cttattactc gtgaacttat gaaagaactc attcaagccg 3960 ttcccaaaaa acccagaatt gaagatcttg ctcaactggt catgcaagta gtagatcgcc 4020 atgatctgat actttaccaa gctatcctct ccaagttctc ccacgtacgg caagtacggc 4080 aacgagctct ggaagctttg ttgtttgggg tcata 4115 86 3948 DNA Candida tropicalis 86 gacctgtgac gcttccggtg tcttgccacc agtctccaag ttgaccgacg cccaagtcat 60 gtaccacttt atttccggtt acacttccaa gatggctggt actgaagaag gtgtcacgga 120 accacaagct actttctccg cttgtttcgg tcaaccattc ttggtgttgc acccaatgaa 180 gtacgctcaa caattgtctg acaagatctc gcaacacaag gctaacgcct ggttgttgaa 240 caccggttgg gttggttctt ctgctgctag aggtggtaag agatgctcat tgaagtacac 300 cagagccatt ttggacgcta tccactctgg tgaattgtcc aaggttgaat acgaaacttt 360 cccagtcttc aacttgaatg tcccaacctc ctgtccaggt gtcccaagtg aaatcttgaa 420 cccaaccaag gcctggaccg gaaggtgttg actccttcaa caaggaaatc aagtctttgg 480 ctggtaagtt tgctgaaaac ttcaagacct atgctgacca agctaccgct gaagtgagag 540 ctgcaggtcc agaagcttaa agatatttat tcattattta gtttgcctat ttatttctca 600 ttacccatca tcattcaaca ctatatataa agttacttcg gatatcattg taatcgtgcg 660 tgtcgcaatt ggatgatttg gaactgcgct tgaaacggat tcatgcacga agcggagata 720 aaagattacg taatttatct cctgagacaa ttttagccgt gttcacacgc ccttctttgt 780 tctgagcgaa ggataaataa ttagacttcc acagctcatt ctaatttccg tcacgcgaat 840 attgaagggg ggtacatgtg gccgctgaat gtgggggcag taaacgcagt ctctcctctc 900 ccaggaatag tgcaacggag gaaggataac ggatagaaag cggaatgcga ggaaaatttt 960 gaacgcgcaa gaaaagcaat atccgggcta ccaggttttg agccagggaa cacactccta 1020 tttctgctca atgactgaac atagaaaaaa caccaagacg caatgaaacg cacatggaca 1080 tttagacctc cccacatgtg atagtttgtc ttaacagaaa agtataataa gaacccatgc 1140 cgtccctttt ctttcgccgc ttcaactttt ttttttttat cttacacaca tcacgaccat 1200 gactgtacac gatattatcg ccacatactt caccaaatgg tacgtgatag taccactcgc 1260 tttgattgct tatagagtcc tcgactactt ctatggcaga tacttgatgt acaagcttgg 1320 tgctaaacca tttttccaga aacagacaga cggctgtttc ggattcaaag ctccgcttga 1380 attgttgaag aagaagagcg acggtaccct catagacttc acactccagc gtatccacga 1440 tctcgatcgt cccgatatcc caactttcac attcccggtc ttttccatca accttgtcaa 1500 tacccttgag ccggagaaca tcaaggccat cttggccact cagttcaacg atttctcctt 1560 gggtaccaga cactcgcact ttgctccttt gttgggtgat ggtatcttta cgttggatgg 1620 cgccggctgg aagcacagca gatctatgtt gagaccacag tttgccagag aacagatttc 1680 ccacgtcaag ttgttggagc cacacgttca ggtgttcttc aaacacgtca gaaaggcaca 1740 gggcaagact tttgacatcc aggaattgtt tttcagattg accgtcgact ccgccaccga 1800 gtttttgttt ggtgaatccg ttgagtcctt gagagatgaa tctatcggca tgtccatcaa 1860 tgcgcttgac tttgacggca aggctggctt tgctgatgct tttaactatt cgcagaatta 1920 tttggcttcg agagcggtta tgcaacaatt gtactgggtg ttgaacggga aaaagtttaa 1980 ggagtgcaac gctaaagtgc acaagtttgc tgactactac gtcaacaagg ctttggactt 2040 gacgcctgaa caattggaaa agcaggatgg ttatgtgttt ttgtacgaat tggtcaagca 2100 aaccagagac aagcaagtgt tgagagacca attgttgaac atcatggttg ctggtagaga 2160 caccaccgcc ggtttgttgt cgtttgtttt ctttgaattg gccagaaacc cagaagttac 2220 caacaagttg agagaagaaa ttgaggacaa gtttggactc ggtgagaatg ctagtgttga 2280 agacatttcc tttgagtcgt tgaagtcctg tgaatacttg aaggctgttc tcaacgaaac 2340 cttgagattg tacccatccg tgccacagaa tttcagagtt gccaccaaga acactaccct 2400 cccaagaggt ggtggtaagg acgggttgtc tcctgttttg gtgagaaagg gtcagaccgt 2460 tatttacggt gtctacgcag cccacagaaa cccagctgtt tacggtaagg acgctcttga 2520 gtttagacca gagagatggt ttgagccaga gacaaagaag cttggctggg ccttcctccc 2580 attcaacggt ggtccaagaa tctgtttggg acagcagttt gccttgacag aagcttcgta 2640 tgtcactgtc aggttgctcc aggagtttgc acacttgtct atggacccag acaccgaata 2700 tccacctaag aaaatgtcgc atttgaccat gtcgcttttc gacggtgcca atattgagat 2760 gtattagagg gtcatgtgtt attttgattg tttagtttgt aattactgat taggttaatt 2820 catggattgt tatttattga taggggtttg cgcgtgttgc attcacttgg gatcgttcca 2880 ggttgatgtt tccttccatc ctgtcgagtc aaaaggagtt ttgttttgta actccggacg 2940 atgttttaaa tagaaggtcg atctccatgt gattgttttg actgttactg tgattatgta 3000 atctgcggac gttatacaag catgtgattg tggttttgca gccttttgca cgacaaatga 3060 tcgtcagacg attacgtaat ctttgttaga ggggtaaaaa aaaacaaaat ggcagccaga 3120 atttcaaaca ttctgcaaac aatgcaaaaa atgggaaact ccaacagaca aaaaaaaaaa 3180 ctccgcagca ctccgaaccc acagaacaat ggggcgccag aattattgac tattgtgact 3240 tttttacgct aacgctcatt gcagtgtagt gcgtcttaca cggggtattg ctttctacaa 3300 tgcaagggca cagttgaagg tttgcaccta acgttgcccc gtgtcaactc aatttgacga 3360 gtaacttcct aagctcgaat tatgcagctc gtgcgtcaac ctatgtgcag gaaagaaaaa 3420 atccaaaaaa atcgaaaatg cgactttcga ttttgaataa accaaaaaga aaaatgtcgc 3480 acttttttct cgctctcgct ctctcgaccc aaatcacaac aaatcctcgc gcgcagtatt 3540 tcgacgaaac cacaacaaat aaaaaaaaca aattctacac cacttctttt tcttcaccag 3600 tcaacaaaaa acaacaaatt atacaccatt tcaacgattt ttgctcttat aaatgctata 3660 taatggttta attcaactca ggtatgttta ttttactgtt ttcagctcaa gtatgttcaa 3720 atactaacta cttttgatgt ttgtcgcttt tctagaatca aaacaacgcc cacaacacgc 3780 cgagcttgtc gaatagacgg tttgtttact cattagatgg tcccagatta cttttcaagc 3840 caaagtctct cgagttttgt ttgctgtttc cccaattcct aactatgaag ggtttttata 3900 aggtccaaag accccaaggc atagtttttt tggttccttc ttgtcgtg 3948 87 3755 DNA Candida tropicalis 87 gctcaacaat tgtctgacaa gatctcgcaa cacaaggcta acgcctggtt gttgaacact 60 ggttgggttg gttcttctgc tgctagaggt ggtaagagat gttcattgaa gtacaccaga 120 gccattttgg acgctatcca ctctggtgaa ttgtccaagg ttgaatacga gactttccca 180 gtcttcaact tgaatgtccc aacctcctgc ccaggtgtcc caagtgaaat cttgaaccca 240 accaaggcct ggaccgaagg tgttgactcc ttcaacaagg aaatcaagtc tttggctggt 300 aagtttgctg aaaacttcaa gacctatgct gaccaagcta ccgctgaagt tagagctgca 360 ggtccagaag cttaaagata tttattcact atttagtttg cctatttatt tctcatcacc 420 catcatcatt caacaatata tataaagtta tttcggaact catatatcat tgtaatcgtg 480 cgtgttgcaa ttgggtaatt tgaaactgta gttggaacgg attcatgcac gatgcggaga 540 taacacgaga ttatctccta agacaatttt ggcctcattc acacgccctt cttctgagct 600 aaggataaat aattagactt cacaagttca ttaaaatatc cgtcacgcga aaactgcaac 660 aataaggaag gggggggtag acgtagccga tgaatgtggg gtgccagtaa acgcagtctc 720 tctctccccc cccccccccc ccccctcagg aatagtacaa cgggggaagg ataacggata 780 gcaagtggaa tgcgaggaaa attttgaatg cgcaaggaaa gcaatatccg ggctatcagg 840 ttttgagcca ggggacacac tcctcttctg cacaaaaact taacgtagac aaaaaaaaaa 900 aactccacca agacacaatg aatcgcacat ggacatttag acctccccac atgtgaaagc 960 ttctctggcg aaagcaaaaa aagtataata aggacccatg ccttccctct tcctgggccg 1020 tttcaacttt ttctttttct ttgtctatca acacacacac acctcacgac catgactgca 1080 caggatatta tcgccacata catcaccaaa tggtacgtga tagtaccact cgctttgatt 1140 gcttataggg tcctcgacta cttttacggc agatacttga tgtacaagct tggtgctaaa 1200 ccgtttttcc agaaacaaac agacggttat ttcggattca aagctccact tgaattgtta 1260 aaaaagaaga gtgacggtac cctcatagac ttcactctcg agcgtatcca agcgctcaat 1320 cgtccagata tcccaacttt tacattccca atcttttcca tcaaccttat cagcaccctt 1380 gagccggaga acatcaaggc tatcttggcc acccagttca acgatttctc cttgggcacc 1440 agacactcgc actttgctcc tttgttgggc gatggtatct ttaccttgga cggtgccggc 1500 tggaagcaca gcagatctat gttgagacca cagtttgcca gagaacagat ttcccacgtc 1560 aagttgttgg agccacacat gcaggtgttc ttcaagcacg tcagaaaggc acagggcaag 1620 acttttgaca tccaagaatt gtttttcaga ttgaccgtcg actccgccac tgagtttttg 1680 tttggtgaat ccgttgagtc cttgagagat gaatctattg ggatgtccat caatgcactt 1740 gactttgacg gcaaggctgg ctttgctgat gcttttaact actcgcagaa ctatttggct 1800 tcgagagcgg ttatgcaaca attgtactgg gtgttgaacg ggaaaaagtt taaggagtgc 1860 aacgctaaag tgcacaagtt tgctgactat tacgtcagca aggctttgga cttgacacct 1920 gaacaattgg aaaagcagga tggttatgtg ttcttgtacg agttggtcaa gcaaaccaga 1980 gacaggcaag tgttgagaga ccagttgttg aacatcatgg ttgccggtag agacaccacc 2040 gccggtttgt tgtcgtttgt tttctttgaa ttggccagaa acccagaggt gaccaacaag 2100 ttgagagaag aaatcgagga caagtttggt cttggtgaga atgctcgtgt tgaagacatt 2160 tcctttgagt cgttgaagtc atgtgaatac ttgaaggctg ttctcaacga aactttgaga 2220 ttgtacccat ccgtgccaca gaatttcaga gttgccacca aaaacactac ccttccaagg 2280 ggaggtggta aggacgggtt atctcctgtt ttggtcagaa agggtcaaac cgttatgtac 2340 ggtgtctacg ctgcccacag aaacccagct gtctacggta aggacgccct tgagtttaga 2400 ccagagaggt ggtttgagcc agagacaaag aagcttggct gggccttcct tccattcaac 2460 ggtggtccaa gaatttgctt gggacagcag tttgccttga cagaagcttc gtatgtcact 2520 gtcagattgc tccaagagtt tggacacttg tctatggacc ccaacaccga atatccacct 2580 aggaaaatgt cgcatttgac catgtccctt ttcgacggtg ccaacattga gatgtattag 2640 aggatcatgt gttatttttg attggtttag tctgtttgta gctattgatt aggttaattc 2700 acggattgtt atttattgat agggggtgcg tgtgtgtgtg tgtgttgcat tcacatggga 2760 tcgttccagg ttgttgtttc cttccatcct gttgagtcaa aaggagtttt gttttgtaac 2820 tccggacgat gtcttagata gaaggtcgat ctccatgtga ttgtttgact gctactctga 2880 ttatgtaatc tgtaaagcct agacgttatg caagcatgtg attgtggttt ttgcaacctg 2940 tttgcacgac aaatgatcga cagtcgatta cgtaatccat attatttaga ggggtaataa 3000 aaaataaatg gcagccagaa tttcaaacat tttgcaaaca atgcaaaaga tgagaaactc 3060 caacagaaaa aataaaaaaa ctccgcagca ctccgaacca acaaaacaat ggggggcgcc 3120 agaattattg actattgtga ctttttttta ttttttccgt taactttcat tgcagtgaag 3180 tgtgttacac ggggtggtga tggtgttggt ttctacaatg caagggcaca gttgaaggtt 3240 tccacataac gttgcaccat atcaactcaa tttatcctca ttcatgtgat aaaagaagag 3300 ccaaaaggta attggcagac cccccaaggg gaacacggag tagaaagcaa tggaaacacg 3360 cccatgacag tgccatttag cccacaacac atctagtatt cttttttttt tttgtgcgca 3420 ggtgcacacc tggactttag ttattgcccc ataaagttaa caatctcacc tttggctctc 3480 ccagtgtctc cgcctccaga tgctcgtttt acaccctcga gctaacgaca acacaacacc 3540 catgagggga atgggcaaag ttaaacactt ttggtttcaa tgattcctat ttgctactct 3600 cttgttttgt gttttgattt gcaccatgtg aaataaacga caattatata taccttttcg 3660 tctgtcctcc aatgtctctt tttgctgcca ttttgctttt tgctttttgc ttttgcactc 3720 tctcccactc ccacaatcag tgcagcaaca cacaa 3755 88 3900 DNA Candida tropicalis 88 gacatcataa tgacccggtt atttcgccct caggttgctt atttgagccg taaagtgcag 60 tagaaacttt gccttgggtt caaactctag tataatggtg ataactggtt gcactcttgc 120 cataggcatg aaaataggcc gttatagtac tatatttaat aagcgtagga gtataggatg 180 catatgaccg gtttttctat atttttaaga taatctctag taaattttgt attctcagta 240 ggatttcatc aaatttcgca accaattctg gcgaaaaaat gattctttta cgtcaaaagc 300 tgaatagtgc agtttaaagc acctaaaatc acatatacag cctctagata cgacagagaa 360 gctctttatg atctgaagaa gcattagaat agctactatg agccactatt ggtgtatata 420 ttagggattg gtgcaattaa gtacgtacta ataaacagaa gaaaatactt aaccaatttc 480 tggtgtatac ttagtggtga gggacctttt ctgaacattc gggtcaaact tttttttgga 540 gtgcgacatc gatttttcgt ttgtgtaata atagtgaacc tttgtgtaat aaatcttcat 600 gcaagacttg cataattcga gcttgggagt tcacgccaat ttgacctcgt tcatgtgata 660 aaagaaaagc caaaaggtaa ttagcagacg caatgggaac atggagtgga aagcaatgga 720 agcacgccca ggacggagta atttagtcca cactacatct gggggttttt tttttgtgcg 780 caagtacaca cctggacttt agtttttgcc ccataaagtt aacaatctaa cctttggctc 840 tccaactctc tccgccccca aatattcgtt tttacaccct caagctagcg acagcacaac 900 acccattaga ggaatggggc aaagttaaac acttttggct tcaatgattc ctattcgcta 960 ctacattctt ctcttgtttt gtgctttgaa ttgcaccatg tgaaataaac gacaattata 1020 tatacctttt catccctcct cctatatctc tttttgctac attttgtttt ttacgtttct 1080 tgcttttgca ctctcccact cccacaaaga aaaaaaaact acactatgtc gtcttctcca 1140 tcgtttgccc aagaggttct cgctaccact agtccttaca tcgagtactt tcttgacaac 1200 tacaccagat ggtactactt catacctttg gtgcttcttt cgttgaactt tataagtttg 1260 ctccacacaa ggtacttgga acgcaggttc cacgccaagc cactcggtaa ctttgtcagg 1320 gaccctacgt ttggtatcgc tactccgttg cttttgatct acttgaagtc gaaaggtacg 1380 gtcatgaagt ttgcttgggg cctctggaac aacaagtaca tcgtcagaga cccaaagtac 1440 aagacaactg ggctcaggat tgttggcctc ccattgattg aaaccatgga cccagagaac 1500 atcaaggctg ttttggctac tcagttcaat gatttctctt tgggaaccag acacgatttc 1560 ttgtactcct tgttgggtga cggtattttc accttggacg gtgctggctg gaaacatagt 1620 agaactatgt tgagaccaca gtttgctaga gaacaggttt ctcacgtcaa gttgttggag 1680 ccacacgttc aggtgttctt caagcacgtt agaaagcacc gcggtcaaac gttcgacatc 1740 caagaattgt tcttcaggtt gaccgtcgac tccgccaccg agttcttgtt tggtgagtct 1800 gctgaatcct tgagggacga atctattgga ttgaccccaa ccaccaagga tttcgatggc 1860 agaagagatt tcgctgacgc tttcaactat tcgcagactt accaggccta cagatttttg 1920 ttgcaacaaa tgtactggat cttgaatggc tcggaattca gaaagtcgat tgctgtcgtg 1980 cacaagtttg ctgaccacta tgtgcaaaag gctttggagt tgaccgacga tgacttgcag 2040 aaacaagacg gctatgtgtt cttgtacgag ttggctaagc aaaccagaga cccaaaggtc 2100 ttgagagacc agttattgaa cattttggtt gccggtagag acacgaccgc cggtttgttg 2160 tcatttgttt tctacgagtt gtcaagaaac cctgaggtgt ttgctaagtt gagagaggag 2220 gtggaaaaca gatttggact cggtgaagaa gctcgtgttg aagagatctc gtttgagtcc 2280 ttgaagtctt gtgagtactt gaaggctgtc atcaatgaaa ccttgagatt gtacccatcg 2340 gttccacaca actttagagt tgctaccaga aacactaccc tcccaagagg tggtggtgaa 2400 gatggatact cgccaattgt cgtcaagaag ggtcaagttg tcatgtacac tgttattgct 2460 acccacagag acccaagtat ctacggtgcc gacgctgacg tcttcagacc agaaagatgg 2520 tttgaaccag aaactagaaa gttgggctgg gcatacgttc cattcaatgg tggtccaaga 2580 atctgtttgg gtcaacagtt tgccttgacc gaagcttcat acgtcactgt cagattgctc 2640 caggagtttg cacacttgtc tatggaccca gacaccgaat atccaccaaa attgcagaac 2700 accttgacct tgtcgctctt tgatggtgct gatgttagaa tgtactaagg ttgcttttcc 2760 ttgctaattt tcttctgtat agcttgtgta tttaaattga atcggcaatt gatttttctg 2820 ataccaataa ccgtagtgcg atttgaccaa aaccgttcaa actttttgtt ctctcgttga 2880 cgtgctcgct catcagcact gtttgaagac gaaagagaaa attttttgta aacaacactg 2940 tccaaattta cccaacgtga accattatgc aaatgagcgg ccctttcaac tggtcgctgg 3000 aagcattcgg ggatatctac aacgccctta agtttgaaac agacattgat ttagacacca 3060 tagatttcag cggcatcaag aatgaccttg cccacatttt gacgacccca acaccactgg 3120 aagaatcacg ccagaaacta ggcgatggat ccaagcctgt gaccttgccc aatggagacg 3180 aagtggagtt gaaccaagcg ttcctagaag ttaccacatt attgtcgaat gagtttgact 3240 tggaccaatt gaacgcggca gagttgttat actacgctgg cgacatatcc tacaagaagg 3300 gcacatcaat cgcagacagt gccagattgt cttattattt gagagcaaac tacatcttga 3360 acatacttgg gtatttgatt tcgaagcagc gattggattt gatagtcacg gacaacgacg 3420 cgttgtttga tagtattttg aaaagttttg aaaagatcta caagttgata agcgtgttga 3480 acgatatgat tgacaagcaa aaggtgacaa gcgacatcaa cagtctagca ttcatcaatt 3540 gcatcaacta ctcgagaggt caactattct ccgcacacga acttttggga ctggttttgt 3600 ttggattggt cgacatctat ttcaaccagt ttggcacatt agacaactac aagaaggtat 3660 tggcattgat actgaagaac atcagcgatg aagacatctt gatcatacac ttcctcccat 3720 cgacactaca attgtttaag ctggtgttgg acaagaaaga cgacgctgca gttgaacagt 3780 tctacaagta catcacttca acagtgtcac gagactacaa ctccaacatc ggctccacag 3840 ccaaagatga tatcgatttg tccaaaacca aactcagtgg ctttgaggtg ttgacgagtt 3900 89 3668 DNA Candida tropicalis 89 cctgcagaat tcgcggccgc gtcgacagag tagcagttat gcaagcatgt gattgtggtt 60 tttgcaacct gtttgcacga caaatgatcg acagtcgatt acgtaatcca tattatttag 120 aggggtaata aaaaataaat ggcagccaga atttcaaaca ttttgcaaac aatgcaaaag 180 atgagaaact ccaacagaaa aaataaaaaa actccgcagc actccgaacc aacaaaacaa 240 tggggggcgc cagaattatt gactattgtg actttttttt attttttccg ttaactttca 300 ttgcagtgaa gtgtgttaca cggggtggtg atggtgttgg tttctacaat gcaagggcac 360 agttgaaggt ttccacataa cgttgcacca tatcaactca atttatcctc attcatgtga 420 taaaagaaga gccaaaaggt aattggcaga ccccccaagg ggaacacgga gtagaaagca 480 atggaaacac gcccatgaca gtgccattta gcccacaaca catctagtat tctttttttt 540 ttttgtgcgc aggtgcacac ctggacttta gttattgccc cataaagtta acaatctcac 600 ctttggctct cccagtgtct ccgcctccag atgctcgttt tacaccctcg agctaacgac 660 aacacaacac ccatgagggg aatgggcaaa gttaaacact tttggtttca atgattccta 720 tttgctactc tcttgttttg tgttttgatt tgcaccatgt gaaataaacg acaattatat 780 ataccttttc gtctgtcctc caatgtctct ttttgctgcc attttgcttt ttgctttttg 840 cttttgcact ctctcccact cccacaatca gtgcagcaac acacaaagaa gaaaaataaa 900 aaaacctaca ctatgtcgtc ttctccatcg tttgctcagg aggttctcgc taccactagt 960 ccttacatcg agtactttct tgacaactac accagatggt actacttcat ccctttggtg 1020 cttctttcgt tgaacttcat cagcttgctc cacacaaagt acttggaacg caggttccac 1080 gccaagccgc tcggtaacgt cgtgttggat cctacgtttg gtatcgctac tccgttgatc 1140 ttgatctact taaagtcgaa aggtacagtc atgaagtttg cctggagctt ctggaacaac 1200 aagtacattg tcaaagaccc aaagtacaag accactggcc ttagaattgt cggcctccca 1260 ttgattgaaa ccatagaccc agagaacatc aaagctgtgt tggctactca gttcaacgat 1320 ttctccttgg gaactagaca cgatttcttg tactccttgt tgggcgatgg tatttttacc 1380 ttggacggtg ctggctggaa acacagtaga actatgttga gaccacagtt tgctagagaa 1440 caggtttccc acgtcaagtt gttggaacca cacgttcagg tgttcttcaa gcacgttaga 1500 aaacaccgcg gtcagacttt tgacatccaa gaattgttct tcagattgac cgtcgactcc 1560 gccaccgagt tcttgtttgg tgagtctgct gaatccttga gagacgactc tgttggtttg 1620 accccaacca ccaaggattt cgaaggcaga ggagatttcg ctgacgcttt caactactcg 1680 cagacttacc aggcctacag atttttgttg caacaaatgt actggatttt gaatggcgcg 1740 gaattcagaa agtcgattgc catcgtgcac aagtttgctg accactatgt gcaaaaggct 1800 ttggagttga ccgacgatga cttgcagaaa caagacggct atgtgttctt gtacgagttg 1860 gctaagcaaa ctagagaccc aaaggtcttg agagaccagt tgttgaacat tttggttgcc 1920 ggtagagaca cgaccgccgg tttgttgtcg tttgtgttct acgagttgtc gagaaaccct 1980 gaagtgtttg ccaagttgag agaggaggtg gaaaacagat ttggactcgg cgaagaggct 2040 cgtgttgaag agatctcttt tgagtccttg aagtcctgtg agtacttgaa ggctgtcatc 2100 aatgaagcct tgagattgta cccatctgtt ccacacaact tcagagttgc caccagaaac 2160 actacccttc caagaggcgg tggtaaagac ggatgctcgc caattgttgt caagaagggt 2220 caagttgtca tgtacactgt cattggtacc cacagagacc caagtatcta cggtgccgac 2280 gccgacgtct tcagaccaga aagatggttc gagccagaaa ctagaaagtt gggctgggca 2340 tatgttccat tcaatggtgg tccaagaatc tgtttgggtc agcagtttgc cttgactgaa 2400 gcttcatacg tcactgtcag attgctccaa gagtttggaa acttgtccct ggatccaaac 2460 gctgagtacc caccaaaatt gcagaacacc ttgaccttgt cactctttga tggtgctgac 2520 gttagaatgt tctaaggttg cttatccttg ctagtgttat ttatagtttg tgtatttaaa 2580 ttgaatcggc gattgatttt tctggtacta ataactgtag tgggttttga ccaaaaccgt 2640 tcaaactttt tttttttttt tcttccccct accttcgttg ctcgctcatc agcactgttt 2700 gaaaacgaaa aaagaaaatt ttttgtaaac aacattgccc aaacttaccc aacgtgaacc 2760 attataacca aatgagcggc gctttcaact ggtcactgga ggcattcggg gatatctaca 2820 acacccttaa gtttgaggaa gacattgatt tagacaccat agatttcagc ggcatcaaga 2880 atgaccttgt ccacattttg acaaccccaa caccactgga agaatcgcgc cagaaactag 2940 gcgatggatc caagcctgtg gccttgccca atggagacga agtggagttg aaccaagcgt 3000 tcctagaagt taccacatta ttgtcgaacg agtttgactt ggaccaattg aacgcggccg 3060 agttgttata ctacgccggc gacatatcct acaagaaggg cacatcaatt gccgacagtg 3120 ccagattgtc ttactatttg agagcaaact acatcttgaa catacttggg tactttattt 3180 cgaagcagcg attggatgtg atagtcaccg acaacaacgc gttgtttgat aatattttga 3240 aaagttttga aaagatctac aagttgataa gcgcgttgaa cgatatgatt gacaagcaaa 3300 aggtgacaag cgacatcaac agtctagcat ttatcaactg catcaactac tcgaggggtc 3360 aactattctc cgcacacgaa cttttgggac tggttttgtt tggattggtt gacaactatt 3420 tcaaccagtt tggctcatta gacaactaca agaaagtatt ggcattgata ctgaagaaca 3480 tcagtgatga agatatcttg atcgtacgct tcctcccatc gacactacaa ttgtttaagc 3540 tggtgttgga taagaaagac gacgccactg ttgaccagtt ctacaagtac atcacctcaa 3600 cagtgtcgca agactacaac tccaacatcg gagccacagc caaagatgat atcgatttgt 3660 ccaaagcc 3668 90 3826 DNA Candida tropicalis 90 tggagtcgcc agacttgctc acttttgact cccttcgaaa ctcaaagtac gttcaggcgg 60 tgctcaacga aacgctccgt atctacccgg gggtaccacg aaacatgaag acagctacgt 120 gcaacacgac gttgccacgc ggaggaggca aagacggcaa ggaacctatc ttggtgcaga 180 agggacagtc cgttgggttg attactattg ccacgcagac ggacccagag tattttgggg 240 ccgacgctgg tgagtttaag ccggagagat ggtttgattc aagcatgaag aacttggggt 300 gtaaatactt gccgttcaat gctgggccac ggacttgctt ggggcagcag tacactttga 360 ttgaagcgag ctacttgcta gtccggttgg cccagaccta ccgggcaata gatttgcagc 420 caggatcggc gtacccacca agaaagaagt cgttgatcaa catgagtgct gccgacgggg 480 tgtttgtaaa gctttataag gatgtaacgg tagatggata gttgtgtagg aggagcggag 540 ataaattaga tttgattttg tgtaaggttt tggatgtcaa cctactccgc acttcatgca 600 gtgtgtgtga cacaagggtg tactacgtgt gcgtgtgcgc caagagacag cccaaggggg 660 tggtagtgtg tgttggcgga agtgcatgtg acacaacgcg tgggttctgg ccaatggtgg 720 actaagtgca ggtaagcagc gacctgaaac attcctcaac gcttaagaca ctggtggtag 780 agatgcggac caggctattc ttgtcgtgct acccggcgca tggaaaatca actgcgggaa 840 gaataaattt atccgtagaa tccacagagc ggataaattt gcccacctcc atcatcaacc 900 acgccgccac taactacatc actcccctat tttctctctc tctctttgtc ttactccgct 960 cccgtttcct tagccacaga tacacaccca ctgcaaacag cagcaacaat tataaagata 1020 cgccaggccc accttctttc tttttcttca cttttttgac tgcaactttc tacaatccac 1080 cacagccacc accacagccg ctatgattga acaactccta gaatattggt atgtcgttgt 1140 gccagtgttg tacatcatca aacaactcct tgcatacaca aagactcgcg tcttgatgaa 1200 aaagttgggt gctgctccag tcacaaacaa gttgtacgac aacgctttcg gtatcgtcaa 1260 tggatggaag gctctccagt tcaagaaaga gggcagggct caagagtaca acgattacaa 1320 gtttgaccac tccaagaacc caagcgtggg cacctacgtc agtattcttt tcggcaccag 1380 gatcgtcgtg accaaagatc cagagaatat caaagctatt ttggcaaccc agtttggtga 1440 tttttctttg ggcaagaggc acactctttt taagcctttg ttaggtgatg ggatcttcac 1500 attggacggc gaaggctgga agcacagcag agccatgttg agaccacagt ttgccagaga 1560 acaagttgct catgtgacgt cgttggaacc acacttccag ttgttgaaga agcatattct 1620 taagcacaag ggtgaatact ttgatatcca ggaattgttc tttagattta ccgttgattc 1680 ggccacggag ttcttatttg gtgagtccgt gcactcctta aaggacgaat ctattggtat 1740 caaccaagac gatatagatt ttgctggtag aaaggacttt gctgagtcgt tcaacaaagc 1800 ccaggaatac ttggctatta gaaccttggt gcagacgttc tactggttgg tcaacaacaa 1860 ggagtttaga gactgtacca agctggtgca caagttcacc aactactatg ttcagaaagc 1920 tttggatgct agcccagaag agcttgaaaa gcaaagtggg tatgtgttct tgtacgagct 1980 tgtcaagcag acaagagacc ccaatgtgtt gcgtgaccag tctttgaaca tcttgttggc 2040 cggaagagac accactgctg ggttgttgtc gtttgctgtc tttgagttgg ccagacaccc 2100 agagatctgg gccaagttga gagaggaaat tgaacaacag tttggtcttg gagaagactc 2160 tcgtgttgaa gagattacct ttgagagctt gaagagatgt gagtacttga aagcgttcct 2220 taatgaaacc ttgcgtattt acccaagtgt cccaagaaac ttcagaatcg ccaccaagaa 2280 cacgacattg ccaaggggcg gtggttcaga cggtacctcg ccaatcttga tccaaaaggg 2340 agaagctgtg tcgtatggta tcaactctac tcatttggac cctgtctatt acggccctga 2400 tgctgctgag ttcagaccag agagatggtt tgagccatca accaaaaagc tcggctgggc 2460 ttacttgcca ttcaacggtg gtccaagaat ctgtttgggt cagcagtttg ccttgacgga 2520 agctggctat gtgttggtta gattggtgca agagttctcc cacgttaggc tggacccaga 2580 cgaggtgtac ccgccaaaga ggttgaccaa cttgaccatg tgtttgcagg atggtgctat 2640 tgtcaagttt gactagcggc gtggtgaatg cgtttgattt tgtagtttct gtttgcagta 2700 atgagataac tattcagata aggcgagtgg atgtacgttt tgtaagagtt tccttacaac 2760 cttggtgggg tgtgtgaggt tgaggttgca tcttggggag attacacctt ttgcagctct 2820 ccgtatacac ttgtactctt tgtaacctct atcaatcatg tggggggggg ggttcattgt 2880 ttggccatgg tggtgcatgt taaatccgcc aactacccaa tctcacatga aactcaagca 2940 cactaaaaaa aaaaaagatg ttgggggaaa actttggttt cccttcttag taattaaaca 3000 ctctcactct cactctcact ctctccactc agacaaacca accacctggg ctgcagacaa 3060 ccagaaaaaa aaagaacaaa atccagatag aaaaacaaag ggctggacaa ccataaataa 3120 acaatctagg gtctactcca tcttccactg tttcttcttc ttcagactta gctaacaaac 3180 aactcacttc accatggatt acgcaggcat cacgcgtggc tccatcagag gcgaggcctt 3240 gaagaaactc gcagaattga ccatccagaa ccagccatcc agcttgaaag aaatcaacac 3300 cggcatccag aaggacgact ttgccaagtt gttgtctgcc accccgaaaa tccccaccaa 3360 gcacaagttg aacggcaacc acgaattgtc tgaggtcgcc attgccaaaa aggagtacga 3420 ggtgttgatt gccttgagcg acgccacaaa agacccaatc aaagtgacct cccagatcaa 3480 gatcttgatt gacaagttca aggtgtactt gtttgagttg cctgaccaga agttctccta 3540 ctccatcgtg tccaactccg tcaacatcgc cccctggacc ttgctcgggg agaagttgac 3600 cacgggcttg atcaacttgg ccttccagaa caacaagcag cacttggacg aggtcattga 3660 catcttcaac gagttcatcg acaagttctt tggcaacacg gagccgcaat tgaccaactt 3720 cttgaccttg tgcggtgtgt tggacgggtt gattgaccat gccaacttct tgagcgtgtc 3780 ctcgcggacc ttcaagatct tcttgaactt ggactcgtat gtggac 3826 91 3910 DNA Candida tropicalis 91 ttacaatcat ggagctcgct aggaacccag atgtctggga gaagctccgc gaagaggtca 60 acacgaactt tggcatggag tcgccagact tgctcacttt tgactctctt agaagctcaa 120 agtacgttca ggcggtgctc aacgaaacgc ttcgtatcta cccgggggtg ccacgaaaca 180 tgaagacagc tacgtgcaac acgacgttgc cgcgtggagg aggcaaagac ggtaaggaac 240 ctattttggt gcagaagggc cagtccgttg ggttgattac tattgccacg cagacggacc 300 cagagtattt tggggcagat gctggtgagt tcaaaccgga gagatggttt gattcaagca 360 tgaagaactt ggggtgtaag tacttgccgt tcaatgctgg gccccggact tgtttggggc 420 agcagtacac tttgattgaa gcgagctatt tgctagtcag gttggcgcag acctaccggg 480 taatcgattt gctgccaggg tcggcgtacc caccaagaaa gaagtcgttg atcaatatga 540 gtgctgccga tggggtggtt gtaaagtttc acaaggatct agatggatat gtaaggtgtg 600 taggaggagc ggagataaat tagatttgat tttgtgtaag gtttagcacg tcaagctact 660 ccgcactttg tgtgtaggga gcacatactc cgtctgcgcc tgtgccaaga gacggcccag 720 gggtagtgtg tggtggtgga agtgcatgtg acacaatacc ctggttctgg ccaattgggg 780 atttagtgta ggtaagctgc gacctgaaac actcctcaac gcttgagaca ctggtgggta 840 gagatgcggg ccaggaggct attcttgtcg tgctacccgt gcacggaaaa tcgattgagg 900 gaagaacaaa tttatccgtg aaatccacag agcggataaa tttgtcacat tgctgcgttg 960 cccacccaca gcattctctt ttctctctct ttgtcttact ccgctcctgt ttccttatcc 1020 agaaatacac accaactcat ataaagatac gctagcccag ctgtctttct ttttcttcac 1080 tttttttggt gtgttgcttt tttggctgct actttctaca accaccacca ccaccaccac 1140 catgattgaa caaatcctag aatattggta tattgttgtg cctgtgttgt acatcatcaa 1200 acaactcatt gcctacagca agactcgcgt cttgatgaaa cagttgggtg ctgctccaat 1260 cacaaaccag ttgtacgaca acgttttcgg tatcgtcaac ggatggaagg ctctccagtt 1320 caagaaagag ggcagagctc aagagtacaa cgatcacaag tttgacagct ccaagaaccc 1380 aagcgtcggc acctatgtca gtattctttt tggcaccaag attgtcgtga ccaaggatcc 1440 agagaatatc aaagctattt tggcaaccca gtttggcgat ttttctttgg gcaagagaca 1500 cgctcttttt aaacctttgt taggtgatgg gatcttcacc ttggacggcg aaggctggaa 1560 gcatagcaga tccatgttaa gaccacagtt tgccagagaa caagttgctc atgtgacgtc 1620 gttggaacca cacttccagt tgttgaagaa gcatatcctt aaacacaagg gtgagtactt 1680 tgatatccag gaattgttct ttagatttac tgtcgactcg gccacggagt tcttatttgg 1740 tgagtccgtg cactccttaa aggacgaaac tatcggtatc aaccaagacg atatagattt 1800 tgctggtaga aaggactttg ctgagtcgtt caacaaagcc caggagtatt tgtctattag 1860 aattttggtg cagaccttct actggttgat caacaacaag gagtttagag actgtaccaa 1920 gctggtgcac aagtttacca actactatgt tcagaaagct ttggatgcta ccccagagga 1980 acttgaaaag caaggcgggt atgtgttctt gtatgagctt gtcaagcaga cgagagaccc 2040 caaggtgttg cgtgaccagt ctttgaacat cttgttggca ggaagagaca ccactgctgg 2100 gttgttgtcc tttgctgtgt ttgagttggc cagaaaccca cacatctggg ccaagttgag 2160 agaggaaatt gaacagcagt ttggtcttgg agaagactct cgtgttgaag agattacctt 2220 tgagagcttg aagagatgtg agtacttgaa agcgttcctt aacgaaacct tgcgtgttta 2280 cccaagtgtc ccaagaaact tcagaatcgc caccaagaat acaacattgc caaggggtgg 2340 tggtccagac ggtacccagc caatcttgat ccaaaaggga gaaggtgtgt cgtatggtat 2400 caactctacc cacttagatc ctgtctatta tggccctgat gctgctgagt tcagaccaga 2460 gagatggttt gagccatcaa ccagaaagct cggctgggct tacttgccat tcaacggtgg 2520 gccacgaatc tgtttgggtc agcagtttgc cttgaccgaa gctggttacg ttttggtcag 2580 attggtgcaa gagttctccc acattaggct ggacccagat gaagtgtatc caccaaagag 2640 gttgaccaac ttgaccatgt gtttgcagga tggtgctatt gtcaagtttg actagtacgt 2700 atgagtgcgt ttgattttgt agtttctgtt tgcagtaatg agataactat tcagataagg 2760 cgggtggatg tacgttttgt aagagtttcc ttacaaccct ggtgggtgtg tgaggttgca 2820 tcttagggag agatagcacc ttttgcagct ctccgtatac agttttactc tttgtaacct 2880 atgccaatca tgtggggatt cattgtttgc ccatggtggt gcatgcaaaa tccccccaac 2940 tacccaatct cacatgaaac tcaagcacac tagaaaaaaa agatgttgcg tgggttcttt 3000 tgatgttggg gaaaactttc gtttcctttc tcagtaatta aacgttctca ctcagacaaa 3060 ccacctgggc tgcagacaac cagaaaaaac aaaatccaga tagaagaaga aagggctgga 3120 caaccataaa taaacaacct agggtccact ccatctttca cttcttcttc ttcagactta 3180 tctaacaaac gactcacttc accatggatt acgcaggtat cacgcgtggg tccatcagag 3240 gcgaagcctt gaagaaactc gccgagttga ccatccagaa ccagccatcc agcttgaaag 3300 aaatcaacac cggcatccag aaggacgact ttgccaagtt gttgtcttcc accccgaaaa 3360 tccacaccaa gcacaagttg aatggcaacc acgaattgtc cgaagtcgcc attgccaaaa 3420 aggagtacga ggtgttgatt gccttgagcg acgccacgaa agaaccaatc aaagtcacct 3480 cccagatcaa gatcttgatt gacaagttca aggtgtactt gtttgagttg cccgaccaga 3540 agttctccta ctccatcgtg tccaactccg ttaacattgc cccctggacc ttgctcggtg 3600 agaagttgac cacgggcttg atcaacttgg cgttccagaa caacaagcag cacttggacg 3660 aagtcatcga catcttcaac gagttcatcg acaagttctt tggcaacaca gagccgcaat 3720 tgaccaactt cttgaccttg tccggtgtgt tggacgggtt gattgaccat gccaacttct 3780 tgagcgtgtc ctccaggacc ttcaagatct tcttgaactt ggactcgttt gtggacaact 3840 cggacttctt gaacgacgtg gagaactact ccgacttttt gtacgacgag ccgaacgagt 3900 accagaactt 3910 92 3150 DNA Candida tropicalis 92 gaattctttg gatctaattc cagctgatct tgctaatcct tatcaacgta gttgtgatca 60 ttgtttgtct gaattataca caccagtgga agaatatggt ctaatttgca cgtcccactg 120 gcattgtgtg tttgtggggg ggggggggtg cacacatttt tagtgccatt ctttgttgat 180 tacccctccc ccctatcatt cattcccaca ggattagttt tttcctcact ggaattcgct 240 gtccacctgt caaccccccc cccccccccc cccactgccc taccctgccc tgccctgcac 300 gtcctgtgtt ttgtgctgtg tctttcccac gctataaaag ccctggcgtc cggccaaggt 360 ttttccaccc agccaaaaaa acagtctaaa aaatttggtt gatccttttt ggttgcaagg 420 ttttccacca ccacttccac cacctcaact attcgaacaa aagatgctcg atcagatctt 480 acattactgg tacattgtct tgccattgtt ggccattatc aaccagatcg tggctcatgt 540 caggaccaat tatttgatga agaaattggg tgctaagcca ttcacacacg tccaacgtga 600 cgggtggttg ggcttcaaat tcggccgtga attcctcaaa gcaaaaagtg ctgggagact 660 ggttgattta atcatctccc gtttccacga taatgaggac actttctcca gctatgcttt 720 tggcaaccat gtggtgttca ccagggaccc cgagaatatc aaggcgcttt tggcaaccca 780 gtttggtgat ttttcattgg gcagcagggt caagttcttc aaaccattat tggggtacgg 840 tatcttcaca ttggacgccg aaggctggaa gcacagcaga gccatgttga gaccacagtt 900 tgccagagaa caagttgctc atgtgacgtc gttggaacca cacttccagt tgttgaagaa 960 gcatatcctt aaacacaagg gtgagtactt tgatatccag gaattgttct ttagatttac 1020 tgtcgactcg gccacggagt tcttatttgg tgagtccgtg cactccttaa aggacgagga 1080 aattggctac gacacgaaag acatgtctga agaaagacgc agatttgccg acgcgttcaa 1140 caagtcgcaa gtctacgtgg ccaccagagt tgctttacag aacttgtact ggttggtcaa 1200 caacaaagag ttcaaggagt gcaatgacat tgtccacaag tttaccaact actatgttca 1260 gaaagccttg gatgctaccc cagaggaact tgaaaagcaa ggcgggtatg tgttcttgta 1320 tgagcttgtc aagcagacga gagaccccaa ggtgttgcgt gaccagtctt tgaacatctt 1380 gttggcagga agagacacca ctgctgggtt gttgtccttt gctgtgtttg agttggccag 1440 aaacccacac atctgggcca agttgagaga ggaaattgaa cagcagtttg gtcttggaga 1500 agactctcgt gttgaagaga ttacctttga gagcttgaag agatgtgagt acttgaaggc 1560 cgtgttgaac gaaactttga gattacaccc aagtgtccca agaaacgcaa gatttgcgat 1620 taaagacacg actttaccaa gaggcggtgg ccccaacggc aaggatccta tcttgatcag 1680 gaaggatgag gtggtgcagt actccatctc ggcaactcag acaaatcctg cttattatgg 1740 cgccgatgct gctgatttta gaccggaaag atggtttgaa ccatcaacta gaaacttggg 1800 atgggctttc ttgccattca acggtggtcc aagaatctgt ttgggacaac agtttgcttt 1860 gactgaagcc ggttacgttt tggttagact tgttcaggag tttccaaact tgtcacaaga 1920 ccccgaaacc aagtacccac cacctagatt ggcacacttg acgatgtgct tgtttgacgg 1980 tgcacacgtc aagatgtcat aggtttcccc atacaagtag ttcagtaatt atacactgtt 2040 tttactttct cttcatacca aatggacaaa agttttaagc atgcctaaca acgtgaccgg 2100 acaattgtgt cgcactagta tgtaacaatt gtaaaaatag tgtacactaa tttgtggtgg 2160 ccggagataa attacagttt ggttttgtgt aaactcgcgg atatctctgg cagtttctct 2220 tctccgcagc agctttgcca cgggtttgct ctggggccaa caaattcaaa agggggagaa 2280 acttaacacc ccttatctct ccactctagg ttgtagctct tgtggggatg caattgtcgt 2340 acgtttttta tgttttgtct agactttgat gattacgttg gatttcttat gtctgaggcg 2400 tgcttgaaag aagtgtcaaa atgtgacagg cgacgctatt cgacatgaac gcgaaagggt 2460 tatttgcatc aatacgaggg gctgactcta gtctaggatg gcagtcctag gttgcaaaca 2520 tgttgcacca tatccctcct ggagttggtc gacctcgcct acgccaccct cagcgatcgg 2580 cactttccgt tgttcaatat ttctccttcc cattgttcca ggggttatca acaacgttgc 2640 cggcctcctc cccaaattac aagaaaaata aattgtcgca cggcaccgat ctgtcaaaga 2700 tacagataaa ccttaaatct gcaaaaacaa gacccctccc catagcctag aagcaccagc 2760 aagatgatgg agcaactcct ccagtactgg tacatcgcac tctctgtatg gttcatcctt 2820 cgctacttgg cttcccacgc acgagccgtc tacttgcgcc acaagctcgg cgcggcgcca 2880 ttcacgcaca cccagtacga cggctggtat gggttcaagt ttgggcggga gtttctcaag 2940 gcgaagaaga tcgggcggca gacggacttg gtgcatgcgc ggttccgtgg cggcatggac 3000 accttctcga gctacacttt cggcatccat atcatcctta cccgggaccc ggagaacatc 3060 aaggcggtct tggcgacgca gttcgatgac ttctcgctcg gtggcaggat caggttcttg 3120 aagccgttgt tggggtatgg gatattcacg 3150 93 3579 DNA Candida tropicalis 93 aaaaccgata caagaagaag acagtcaaca agaacgttaa tgtcaaccag gcgccaagaa 60 gacggtttgg cggacttgga agaatgtggc atttgcccat gatgtttatg ttctggagag 120 gtttttcaag gaatcgtcat cctccgccac cacaagaacc accagttaac gagatccata 180 ttcacaaccc accgcaaggt gacaatgctc aacaacaaca gcaacaacaa caacccccac 240 aagaacagtg gaataatgcc agtcaacaaa gagtggtgac agacgaggga gaaaacgcaa 300 gcaacagtgg ttctgatgca agatcagcta caccgcttca tcaggaaaag caggagctcc 360 caccaccata tgcccatcac gagcaacacc agcaggttag tgtatagtag tctgtagtta 420 agtcaatgca atgtaccaat aagactatcc cttcttacaa ccaagttttc tgccgcgcct 480 gtctggcaac agatgctggc cgacacactt tcaactgagt ttggtctaga attcttgcac 540 atgcacgaca aggaaactct tacaaagaca acacttgtgc tctgatgcca cttgatcttg 600 ctaagcctta tcaacgtaat tgagatcatt gtttgtctga attatacaca ccagtggaag 660 aatctggtct aatctgcacg cctcatgggc attgtgtgtt ttgggggggg gggggggggt 720 gcacacattt ttagtgcgaa tgtttgtttg ctggttcccc ctcccccctc ccccctatca 780 tgcccacagg attagttttt tcctcactgg aattcgctgt ccacctgtca accccctcac 840 tgccctgccc tgccctgcac gccctgtgtt ttgtgctgtg gcactcccac gctataaaag 900 ccctggcgta cggccaaggt ttttcctcac agccaaaaaa aaatttggct gatccttttg 960 ggctgcaagg tttttcacca ccaccaccac caccacctca actattcaaa caaaggatgc 1020 tcgaccagat cttccattac tggtacattg tcttgccatt gttggtcatt atcaagcaga 1080 tcgtggctca tgccaggacc aattatttga tgaagaagtt gggcgctaag ccattcacac 1140 atgtccaact agacgggtgg tttggcttca aatttggccg tgaattcctc aaagctaaaa 1200 gtgctgggag gcaggttgat ttaatcatct cccgtttcca cgataatgag gacactttct 1260 ccagctatgc ttttggcaac catgtggtgt tcaccaggga ccccgagaat atcaaggcgc 1320 ttttggcaac ccagtttggt gatttttcat tgggaagcag ggtcaaattc ttcaaaccat 1380 tgttggggta cggtatcttc accttggacg gcgaaggctg gaagcacagc agagccatgt 1440 tgagaccaca gtttgccaga gagcaagttg ctcatgtgac gtcgttggaa ccacatttcc 1500 agttgttgaa gaagcatatt cttaagcaca agggtgaata ctttgatatc caggaattgt 1560 tctttagatt taccgttgat tcagcgacgg agttcttatt tggtgagtcc gtgcactcct 1620 taagggacga ggaaattggc tacgatacga aggacatggc tgaagaaaga cgcaaatttg 1680 ccgacgcgtt caacaagtcg caagtctatt tgtccaccag agttgcttta cagacattgt 1740 actggttggt caacaacaaa gagttcaagg agtgcaacga cattgtccac aagttcacca 1800 actactatgt tcagaaagcc ttggatgcta ccccagagga acttgaaaaa caaggcgggt 1860 atgtgttctt gtacgagctt gccaagcaga cgaaagaccc caatgtgttg cgtgaccagt 1920 ctttgaacat cttgttggct ggaagggaca ccactgctgg gttgttgtcc tttgctgtgt 1980 ttgagttggc caggaaccca cacatctggg ccaagttgag agaggaaatt gaatcacact 2040 ttgggctggg tgaggactct cgtgttgaag agattacctt tgagagcttg aagagatgtg 2100 agtacttgaa agccgtgttg aacgaaacgt tgagattaca cccaagtgtc ccaagaaacg 2160 caagatttgc gattaaagac acgactttac caagaggcgg tggccccaac ggcaaggatc 2220 ctatcttgat cagaaagaat gaggtggtgc aatactccat ctcggcaact cagacaaatc 2280 ctgcttatta tggcgccgat gctgctgatt ttagaccgga aagatggttt gagccatcaa 2340 ctagaaactt gggatgggct tacttgccat tcaacggtgg tccaagaatc tgcttgggac 2400 aacagtttgc tttgaccgaa gccggttacg ttttggttag acttgttcag gaattcccta 2460 gcttgtcaca ggaccccgaa actgagtacc caccacctag attggcacac ttgacgatgt 2520 gcttgtttga cggggcatac gtcaagatgc aataggtttt ggtttgactt tgtttccata 2580 tgcaagtagt tcagtaatta cacactaatt tgtggtggcc ggcgataaat taccgtttgg 2640 ttttgtgtaa aaattcggac atctctggtg gtttcccttc tccgcagcag ctttgccacg 2700 ggtttgctct gcggccaaca aattcgaaag gggggggggg gggggagaaa gttaacaccc 2760 cctgttccca ccgtaggctg tagctcttgt ggggggatgt aattgtcgta cgttttcatg 2820 tttggcccag actttgatga ttacgtaggc tttcttatgt ctaaggcgtg cttgacacaa 2880 gtgtcaaaag gtgacaggcg acgttattcg acatgaacgc aaaagggtaa tttgcatcga 2940 tacgaggggt tgcctctggt ctaagaagga ccccccaggt tgcaaacatg ttgcactgca 3000 tcccactcag agttggtcga ccacgcctac gcttaccctc agcgatcggc actttccgtt 3060 gctcaatatt tctctccccc ctgcttcccc ccattgttcc agggattatc aacaacgttg 3120 ccggtctcct ctcccccccc tccccccagt tatgtacaag aaaattaaat tgtcgcacgg 3180 caccgatacg tcaaagatac agagaaacct taatccctcc catagcctag aagcatcaaa 3240 aagatgattg agcaactcct ccagtactgg tacattgcac tccctgtatg gttcattctc 3300 cgctacgtgg cttcccacgc acgaaccatc tacttgcgcc acaagctcgg cgcggcgccg 3360 ttcacgcaca cccagtacga cggatggtat gggttcaagt ttgggcggga gtttctcaag 3420 gcgaagaaga ttggaaggca gacggacttg gtgcatgcgc ggttccgtgg agggggcatg 3480 gatactttct cgagctatac tttcggcatc catatcattc ttactcggga cccggagaac 3540 atcaaggcgg tcttggcgac gcagttcgat gacttttcg 3579 94 3348 DNA Candida tropicalis 94 gatgtggtgc ttgatttctc gagacacatc cttgtgaggt gccatgaatc tgtacctgtc 60 tgtaagcaca gggaactgct tcaacacctt attgcatatt ctgtctattg caagcgtgtg 120 ctgcaacgat atctgccaag gtatatagca gaacgtgctg atggttcctc cggtcatatt 180 ctgttggtag ttctgcaggt aaatttggat gtcaggtagt ggagggaggt ttgtatcggt 240 tgtgttttct tcttcctctc tctctgattc aacctccacg tctccttcgg gttctgtgtc 300 tgtgtctgag tcgtactgtt ggattaagtc catcgcatgt gtgaaaaaaa gtagcgctta 360 tttagacaac cagttcgttg ggcgggtatc agaaatagtc tgttgtgcac gaccatgagt 420 atgcaacttg acgagacgtc gttaggaatc cacagaatga tagcaggaag cttactacgt 480 gagagattct gcttagagga tgttctcttc ttgttgattc cattaggtgg gtatcatctc 540 cggtggtgac aacttgacac aagcagttcc gagaaccacc cacaacaatc accattccag 600 ctatcacttc tacatgtcaa cctacgatgt atctcatcac catctagttt cttggcaatc 660 gtttatttgt tatgggtcaa catccaatac aactccacca atgaagaaga aaaacggaaa 720 gcagaatacc agaatgacag tgtgagttcc tgaccattgc taatctatgg ctatatctag 780 tttgctatcg tgggatgtga tctgtgtcgt cttcatttgc gtttgtgttt atttcgggta 840 tgaatattgt tatactaaat acttgatgca caaacatggc gctcgagaaa tcgagaatgt 900 gatcaacgat gggttctttg ggttccgctt acctttgcta ctcatgcgag ccagcaatga 960 gggccgactt atcgagttca gtgtcaagag attcgagtcg gcgccacatc cacagaacaa 1020 gacattggtc aaccgggcat tgagcgttcc tgtgatactc accaaggacc cagtgaatat 1080 caaagcgatg ctatcgaccc agtttgatga cttttccctt gggttgagac tacaccagtt 1140 tgcgccgttg ttggggaaag gcatctttac tttggacggc ccagagtgga agcagagccg 1200 atctatgttg cgtccgcaat ttgccaaaga tcgggtttct catatcctgg atctagaacc 1260 gcattttgtg ttgcttcgga agcacattga tggccacaat ggagactact tcgacatcca 1320 ggagctctac ttccggttct cgatggatgt ggcgacgggg tttttgtttg gcgagtctgt 1380 ggggtcgttg aaagacgaag atgcgaggtt cctggaagca ttcaatgagt cgcagaagta 1440 tttggcaact agggcaacgt tgcacgagtt gtactttctt tgtgacgggt ttaggtttcg 1500 ccagtacaac aaggttgtgc gaaagttctg cagccagtgt gtccacaagg cgttagatgt 1560 tgcaccggaa gacaccagcg agtacgtgtt tctccgcgag ttggtcaaac acactcgaga 1620 tcccgttgtt ttacaagacc aagcgttgaa cgtcttgctt gctggacgcg acaccaccgc 1680 gtcgttatta tcgtttgcaa catttgagct agcccggaat gaccacatgt ggaggaagct 1740 acgagaggag gttatcctga cgatgggacc gtccagtgat gaaataaccg tggccgggtt 1800 gaagagttgc cgttacctca aagcaatcct aaacgaaact cttcgactat acccaagtgt 1860 gcctaggaac gcgagatttg ctacgaggaa tacgacgctt cctcgtggcg gaggtccaga 1920 tggatcgttt ccgattttga taagaaaggg ccagccagtg gggtatttca tttgtgctac 1980 acacttgaat gagaaggtat atgggaatga tagccatgtg tttcgaccgg agagatgggc 2040 tgcgttagag ggcaagagtt tgggctggtc gtatcttcca ttcaacggcg gcccgagaag 2100 ctgccttggt cagcagtttg caatccttga agcttcgtat gttttggctc gattgacaca 2160 gtgctacacg acgatacagc ttagaactac cgagtaccca ccaaagaaac tcgttcatct 2220 cacgatgagt cttctcaacg gggtgtacat ccgaactaga acttgattat gtgtttatgg 2280 ttaatcgggg caaagcactg caagtcattg atgtttgtgg aagcccagca ttggtgttcc 2340 ggagcatcaa taaccaatgt cttgaagggt ttgattttct tgaccttctt cttcctgagc 2400 ttctttccgt caaacttgta cagaatggcc atcatttcag gaacaaccac gtacgacggc 2460 cggtaccgca tctggagtat ctcgccgtcg ttcaagtagc acgaaaacag caacgacgtc 2520 accatctgct tcccaatctt gacacccaca gatacccctg cggcttcatg gatcaaaaac 2580 gtcggcaacc ccgcgtatat gtccatgtaa ttctccatgg ccacctccat caacacactg 2640 atggagcgac tgacggtgcc accactgccc tcggttgagt caaggcagta tgatgccggg 2700 atccagtact ccaatgggaa cctctgcacg gtgtcgctgc agtttttgag gcgtatttcg 2760 atccatgatc gttctttggt gctgtagtat aacgagctct tggtgtcctt gaaatggaac 2820 aggttggatg tgttgttgag tttgtctgcg tgcttggttt gcaagtcttc gatcgagcgt 2880 agtgagtaga cagttggcgg gggtggtggc tcgggcttta ttctgtgttt gtgtttcctt 2940 cttagtcttg gaatgacgct gttatcgacg gttcgtagta taagtagcgc caatatgaga 3000 atgtatatcc gcatcaccca agactcttca gcctgttaca acgactgagg ctgttggccg 3060 tgtgaccaat tggtttcttt ggtgacctag attggtcccg cagggaaagc aagggctgct 3120 aggggggcat accaaacaag gtcgtgtaat cagtatctat ggtgctacca tgtgtgtggt 3180 tggggggaaa ttcccgcatt tttgtgtaac gaaagttcta gaaagttctc gtgggttctg 3240 agaatctgct ggaaccatcc acccgcattt ccgttgccaa agtgggaaga gcaatcaacc 3300 caccctgctt tgcccaatca gccattcccc tgggaatata aattcaac 3348 95 523 PRT CANDIDATROPICALIS 95 Met Ala Thr Gln Glu Ile Ile Asp Ser Val Leu Pro Tyr Leu Thr Lys 1 5 10 15 Trp Tyr Thr Val Ile Thr Ala Ala Val Leu Val Phe Leu Ile Ser Thr 20 25 30 Asn Ile Lys Asn Tyr Val Lys Ala Lys Lys Leu Lys Cys Val Asp Pro 35 40 45 Pro Tyr Leu Lys Asp Ala Gly Leu Thr Gly Ile Leu Ser Leu Ile Ala 50 55 60 Ala Ile Lys Ala Lys Asn Asp Gly Arg Leu Ala Asn Phe Ala Asp Glu 65 70 75 80 Val Phe Asp Glu Tyr Pro Asn His Thr Phe Tyr Leu Ser Val Ala Gly 85 90 95 Ala Leu Lys Ile Val Met Thr Val Asp Pro Glu Asn Ile Lys Ala Val 100 105 110 Leu Ala Thr Gln Phe Thr Asp Phe Ser Leu Gly Thr Arg His Ala His 115 120 125 Phe Ala Pro Leu Leu Gly Asp Gly Ile Phe Thr Leu Asp Gly Glu Gly 130 135 140 Trp Lys His Ser Arg Ala Met Leu Arg Pro Gln Phe Ala Arg Asp Gln 145 150 155 160 Ile Gly His Val Lys Ala Leu Glu Pro His Ile Gln Ile Met Ala Lys 165 170 175 Gln Ile Lys Leu Asn Gln Gly Lys Thr Phe Asp Ile Gln Glu Leu Phe 180 185 190 Phe Arg Phe Thr Val Asp Thr Ala Thr Glu Phe Leu Phe Gly Glu Ser 195 200 205 Val His Ser Leu Tyr Asp Glu Lys Leu Gly Ile Pro Thr Pro Asn Glu 210 215 220 Ile Pro Gly Arg Glu Asn Phe Ala Ala Ala Phe Asn Val Ser Gln His 225 230 235 240 Tyr Leu Ala Thr Arg Ser Tyr Ser Gln Thr Phe Tyr Phe Leu Thr Asn 245 250 255 Pro Lys Glu Phe Arg Asp Cys Asn Ala Lys Val His His Leu Ala Lys 260 265 270 Tyr Phe Val Asn Lys Ala Leu Asn Phe Thr Pro Glu Glu Leu Glu Glu 275 280 285 Lys Ser Lys Ser Gly Tyr Val Phe Leu Tyr Glu Leu Val Lys Gln Thr 290 295 300 Arg Asp Pro Lys Val Leu Gln Asp Gln Leu Leu Asn Ile Met Val Ala 305 310 315 320 Gly Arg Asp Thr Thr Ala Gly Leu Leu Ser Phe Ala Leu Phe Glu Leu 325 330 335 Ala Arg His Pro Glu Met Trp Ser Lys Leu Arg Glu Glu Ile Glu Val 340 345 350 Asn Phe Gly Val Gly Glu Asp Ser Arg Val Glu Glu Ile Thr Phe Glu 355 360 365 Ala Leu Lys Arg Cys Glu Tyr Leu Lys Ala Ile Leu Asn Glu Thr Leu 370 375 380 Arg Met Tyr Pro Ser Val Pro Val Asn Phe Arg Thr Ala Thr Arg Asp 385 390 395 400 Thr Thr Leu Pro Arg Gly Gly Gly Ala Asn Gly Thr Asp Pro Ile Tyr 405 410 415 Ile Pro Lys Gly Ser Thr Val Ala Tyr Val Val Tyr Lys Thr His Arg 420 425 430 Leu Glu Glu Tyr Tyr Gly Lys Asp Ala Asn Asp Phe Arg Pro Glu Arg 435 440 445 Trp Phe Glu Pro Ser Thr Lys Lys Leu Gly Trp Ala Tyr Val Pro Phe 450 455 460 Asn Gly Gly Pro Arg Val Cys Leu Gly Gln Gln Phe Ala Leu Thr Glu 465 470 475 480 Ala Ser Tyr Val Ile Thr Arg Leu Ala Gln Met Phe Glu Thr Val Ser 485 490 495 Ser Asp Pro Gly Leu Glu Tyr Pro Pro Pro Lys Cys Ile His Leu Thr 500 505 510 Met Ser His Asn Asp Gly Val Phe Val Lys Met 515 520 96 522 PRT CANDIDATROPICALIS 96 Met Thr Val His Asp Ile Ile Ala Thr Tyr Phe Thr Lys Trp Tyr Val 1 5 10 15 Ile Val Pro Leu Ala Leu Ile Ala Tyr Arg Val Leu Asp Tyr Phe Tyr 20 25 30 Gly Arg Tyr Leu Met Tyr Lys Leu Gly Ala Lys Pro Phe Phe Gln Lys 35 40 45 Gln Thr Asp Gly Cys Phe Gly Phe Lys Ala Pro Leu Glu Leu Leu Lys 50 55 60 Lys Lys Ser Asp Gly Thr Leu Ile Asp Phe Thr Leu Gln Arg Ile His 65 70 75 80 Asp Leu Asp Arg Pro Asp Ile Pro Thr Phe Thr Phe Pro Val Phe Ser 85 90 95 Ile Asn Leu Val Asn Thr Leu Glu Pro Glu Asn Ile Lys Ala Ile Leu 100 105 110 Ala Thr Gln Phe Asn Asp Phe Ser Leu Gly Thr Arg His Ser His Phe 115 120 125 Ala Pro Leu Leu Gly Asp Gly Ile Phe Thr Leu Asp Gly Ala Gly Trp 130 135 140 Lys His Ser Arg Ser Met Leu Arg Pro Gln Phe Ala Arg Glu Gln Ile 145 150 155 160 Ser His Val Lys Leu Leu Glu Pro His Val Gln Val Phe Phe Lys His 165 170 175 Val Arg Lys Ala Gln Gly Lys Thr Phe Asp Ile Gln Glu Leu Phe Phe 180 185 190 Arg Leu Thr Val Asp Ser Ala Thr Glu Phe Leu Phe Gly Glu Ser Val 195 200 205 Glu Ser Leu Arg Asp Glu Ser Ile Gly Met Ser Ile Asn Ala Leu Asp 210 215 220 Phe Asp Gly Lys Ala Gly Phe Ala Asp Ala Phe Asn Tyr Ser Gln Asn 225 230 235 240 Tyr Leu Ala Ser Arg Ala Val Met Gln Gln Leu Tyr Trp Val Leu Asn 245 250 255 Gly Lys Lys Phe Lys Glu Cys Asn Ala Lys Val His Lys Phe Ala Asp 260 265 270 Tyr Tyr Val Asn Lys Ala Leu Asp Leu Thr Pro Glu Gln Leu Glu Lys 275 280 285 Gln Asp Gly Tyr Val Phe Leu Tyr Glu Leu Val Lys Gln Thr Arg Asp 290 295 300 Lys Gln Val Leu Arg Asp Gln Leu Leu Asn Ile Met Val Ala Gly Arg 305 310 315 320 Asp Thr Thr Ala Gly Leu Leu Ser Phe Val Phe Phe Glu Leu Ala Arg 325 330 335 Asn Pro Glu Val Thr Asn Lys Leu Arg Glu Glu Ile Glu Asp Lys Phe 340 345 350 Gly Leu Gly Glu Asn Ala Ser Val Glu Asp Ile Ser Phe Glu Ser Leu 355 360 365 Lys Ser Cys Glu Tyr Leu Lys Ala Val Leu Asn Glu Thr Leu Arg Leu 370 375 380 Tyr Pro Ser Val Pro Gln Asn Phe Arg Val Ala Thr Lys Asn Thr Thr 385 390 395 400 Leu Pro Arg Gly Gly Gly Lys Asp Gly Leu Ser Pro Val Leu Val Arg 405 410 415 Lys Gly Gln Thr Val Ile Tyr Gly Val Tyr Ala Ala His Arg Asn Pro 420 425 430 Ala Val Tyr Gly Lys Asp Ala Leu Glu Phe Arg Pro Glu Arg Trp Phe 435 440 445 Glu Pro Glu Thr Lys Lys Leu Gly Trp Ala Phe Leu Pro Phe Asn Gly 450 455 460 Gly Pro Arg Ile Cys Leu Gly Gln Gln Phe Ala Leu Thr Glu Ala Ser 465 470 475 480 Tyr Val Thr Val Arg Leu Leu Gln Glu Phe Ala His Leu Ser Met Asp 485 490 495 Pro Asp Thr Glu Tyr Pro Pro Lys Lys Met Ser His Leu Thr Met Ser 500 505 510 Leu Phe Asp Gly Ala Asn Ile Glu Met Tyr 515 520 97 522 PRT CANDIDATROPICALIS 97 Met Thr Ala Gln Asp Ile Ile Ala Thr Tyr Ile Thr Lys Trp Tyr Val 1 5 10 15 Ile Val Pro Leu Ala Leu Ile Ala Tyr Arg Val Leu Asp Tyr Phe Tyr 20 25 30 Gly Arg Tyr Leu Met Tyr Lys Leu Gly Ala Lys Pro Phe Phe Gln Lys 35 40 45 Gln Thr Asp Gly Tyr Phe Gly Phe Lys Ala Pro Leu Glu Leu Leu Lys 50 55 60 Lys Lys Ser Asp Gly Thr Leu Ile Asp Phe Thr Leu Glu Arg Ile Gln 65 70 75 80 Ala Leu Asn Arg Pro Asp Ile Pro Thr Phe Thr Phe Pro Ile Phe Ser 85 90 95 Ile Asn Leu Ile Ser Thr Leu Glu Pro Glu Asn Ile Lys Ala Ile Leu 100 105 110 Ala Thr Gln Phe Asn Asp Phe Ser Leu Gly Thr Arg His Ser His Phe 115 120 125 Ala Pro Leu Leu Gly Asp Gly Ile Phe Thr Leu Asp Gly Ala Gly Trp 130 135 140 Lys His Ser Arg Ser Met Leu Arg Pro Gln Phe Ala Arg Glu Gln Ile 145 150 155 160 Ser His Val Lys Leu Leu Glu Pro His Met Gln Val Phe Phe Lys His 165 170 175 Val Arg Lys Ala Gln Gly Lys Thr Phe Asp Ile Gln Glu Leu Phe Phe 180 185 190 Arg Leu Thr Val Asp Ser Ala Thr Glu Phe Leu Phe Gly Glu Ser Val 195 200 205 Glu Ser Leu Arg Asp Glu Ser Ile Gly Met Ser Ile Asn Ala Leu Asp 210 215 220 Phe Asp Gly Lys Ala Gly Phe Ala Asp Ala Phe Asn Tyr Ser Gln Asn 225 230 235 240 Tyr Leu Ala Ser Arg Ala Val Met Gln Gln Leu Tyr Trp Val Leu Asn 245 250 255 Gly Lys Lys Phe Lys Glu Cys Asn Ala Lys Val His Lys Phe Ala Asp 260 265 270 Tyr Tyr Val Ser Lys Ala Leu Asp Leu Thr Pro Glu Gln Leu Glu Lys 275 280 285 Gln Asp Gly Tyr Val Phe Leu Tyr Glu Leu Val Lys Gln Thr Arg Asp 290 295 300 Arg Gln Val Leu Arg Asp Gln Leu Leu Asn Ile Met Val Ala Gly Arg 305 310 315 320 Asp Thr Thr Ala Gly Leu Leu Ser Phe Val Phe Phe Glu Leu Ala Arg 325 330 335 Asn Pro Glu Val Thr Asn Lys Leu Arg Glu Glu Ile Glu Asp Lys Phe 340 345 350 Gly Leu Gly Glu Asn Ala Arg Val Glu Asp Ile Ser Phe Glu Ser Leu 355 360 365 Lys Ser Cys Glu Tyr Leu Lys Ala Val Leu Asn Glu Thr Leu Arg Leu 370 375 380 Tyr Pro Ser Val Pro Gln Asn Phe Arg Val Ala Thr Lys Asn Thr Thr 385 390 395 400 Leu Pro Arg Gly Gly Gly Lys Asp Gly Leu Ser Pro Val Leu Val Arg 405 410 415 Lys Gly Gln Thr Val Met Tyr Gly Val Tyr Ala Ala His Arg Asn Pro 420 425 430 Ala Val Tyr Gly Lys Asp Ala Leu Glu Phe Arg Pro Glu Arg Trp Phe 435 440 445 Glu Pro Glu Thr Lys Lys Leu Gly Trp Ala Phe Leu Pro Phe Asn Gly 450 455 460 Gly Pro Arg Ile Cys Leu Gly Gln Gln Phe Ala Leu Thr Glu Ala Ser 465 470 475 480 Tyr Val Thr Val Arg Leu Leu Gln Glu Phe Gly His Leu Ser Met Asp 485 490 495 Pro Asn Thr Glu Tyr Pro Pro Arg Lys Met Ser His Leu Thr Met Ser 500 505 510 Leu Phe Asp Gly Ala Asn Ile Glu Met Tyr 515 520 98 540 PRT CANDIDATROPICALIS 98 Met Ser Ser Ser Pro Ser Phe Ala Gln Glu Val Leu Ala Thr Thr Ser 1 5 10 15 Pro Tyr Ile Glu Tyr Phe Leu Asp Asn Tyr Thr Arg Trp Tyr Tyr Phe 20 25 30 Ile Pro Leu Val Leu Leu Ser Leu Asn Phe Ile Ser Leu Leu His Thr 35 40 45 Arg Tyr Leu Glu Arg Arg Phe His Ala Lys Pro Leu Gly Asn Phe Val 50 55 60 Arg Asp Pro Thr Phe Gly Ile Ala Thr Pro Leu Leu Leu Ile Tyr Leu 65 70 75 80 Lys Ser Lys Gly Thr Val Met Lys Phe Ala Trp Gly Leu Trp Asn Asn 85 90 95 Lys Tyr Ile Val Arg Asp Pro Lys Tyr Lys Thr Thr Gly Leu Arg Ile 100 105 110 Val Gly Leu Pro Leu Ile Glu Thr Met Asp Pro Glu Asn Ile Lys Ala 115 120 125 Val Leu Ala Thr Gln Phe Asn Asp Phe Ser Leu Gly Thr Arg His Asp 130 135 140 Phe Leu Tyr Ser Leu Leu Gly Asp Gly Ile Phe Thr Leu Asp Gly Ala 145 150 155 160 Gly Trp Lys His Ser Arg Thr Met Leu Arg Pro Gln Phe Ala Arg Glu 165 170 175 Gln Val Ser His Val Lys Leu Leu Glu Pro His Val Gln Val Phe Phe 180 185 190 Lys His Val Arg Lys His Arg Gly Gln Thr Phe Asp Ile Gln Glu Leu 195 200 205 Phe Phe Arg Leu Thr Val Asp Ser Ala Thr Glu Phe Leu Phe Gly Glu 210 215 220 Ser Ala Glu Ser Leu Arg Asp Glu Ser Ile Gly Leu Thr Pro Thr Thr 225 230 235 240 Lys Asp Phe Asp Gly Arg Arg Asp Phe Ala Asp Ala Phe Asn Tyr Ser 245 250 255 Gln Thr Tyr Gln Ala Tyr Arg Phe Leu Leu Gln Gln Met Tyr Trp Ile 260 265 270 Leu Asn Gly Ser Glu Phe Arg Lys Ser Ile Ala Val Val His Lys Phe 275 280 285 Ala Asp His Tyr Val Gln Lys Ala Leu Glu Leu Thr Asp Asp Asp Leu 290 295 300 Gln Lys Gln Asp Gly Tyr Val Phe Leu Tyr Glu Leu Ala Lys Gln Thr 305 310 315 320 Arg Asp Pro Lys Val Leu Arg Asp Gln Leu Leu Asn Ile Leu Val Ala 325 330 335 Gly Arg Asp Thr Thr Ala Gly Leu Leu Ser Phe Val Phe Tyr Glu Leu 340 345 350 Ser Arg Asn Pro Glu Val Phe Ala Lys Leu Arg Glu Glu Val Glu Asn 355 360 365 Arg Phe Gly Leu Gly Glu Glu Ala Arg Val Glu Glu Ile Ser Phe Glu 370 375 380 Ser Leu Lys Ser Cys Glu Tyr Leu Lys Ala Val Ile Asn Glu Thr Leu 385 390 395 400 Arg Leu Tyr Pro Ser Val Pro His Asn Phe Arg Val Ala Thr Arg Asn 405 410 415 Thr Thr Leu Pro Arg Gly Gly Gly Glu Asp Gly Tyr Ser Pro Ile Val 420 425 430 Val Lys Lys Gly Gln Val Val Met Tyr Thr Val Ile Ala Thr His Arg 435 440 445 Asp Pro Ser Ile Tyr Gly Ala Asp Ala Asp Val Phe Arg Pro Glu Arg 450 455 460 Trp Phe Glu Pro Glu Thr Arg Lys Leu Gly Trp Ala Tyr Val Pro Phe 465 470 475 480 Asn Gly Gly Pro Arg Ile Cys Leu Gly Gln Gln Phe Ala Leu Thr Glu 485 490 495 Ala Ser Tyr Val Thr Val Arg Leu Leu Gln Glu Phe Ala His Leu Ser 500 505 510 Met Asp Pro Asp Thr Glu Tyr Pro Pro Lys Leu Gln Asn Thr Leu Thr 515 520 525 Leu Ser Leu Phe Asp Gly Ala Asp Val Arg Met Tyr 530 535 540 99 540 PRT CANDIDATROPICALIS 99 Met Ser Ser Ser Pro Ser Phe Ala Gln Glu Val Leu Ala Thr Thr Ser 1 5 10 15 Pro Tyr Ile Glu Tyr Phe Leu Asp Asn Tyr Thr Arg Trp Tyr Tyr Phe 20 25 30 Ile Pro Leu Val Leu Leu Ser Leu Asn Phe Ile Ser Leu Leu His Thr 35 40 45 Lys Tyr Leu Glu Arg Arg Phe His Ala Lys Pro Leu Gly Asn Val Val 50 55 60 Leu Asp Pro Thr Phe Gly Ile Ala Thr Pro Leu Ile Leu Ile Tyr Leu 65 70 75 80 Lys Ser Lys Gly Thr Val Met Lys Phe Ala Trp Ser Phe Trp Asn Asn 85 90 95 Lys Tyr Ile Val Lys Asp Pro Lys Tyr Lys Thr Thr Gly Leu Arg Ile 100 105 110 Val Gly Leu Pro Leu Ile Glu Thr Ile Asp Pro Glu Asn Ile Lys Ala 115 120 125 Val Leu Ala Thr Gln Phe Asn Asp Phe Ser Leu Gly Thr Arg His Asp 130 135 140 Phe Leu Tyr Ser Leu Leu Gly Asp Gly Ile Phe Thr Leu Asp Gly Ala 145 150 155 160 Gly Trp Lys His Ser Arg Thr Met Leu Arg Pro Gln Phe Ala Arg Glu 165 170 175 Gln Val Ser His Val Lys Leu Leu Glu Pro His Val Gln Val Phe Phe 180 185 190 Lys His Val Arg Lys His Arg Gly Gln Thr Phe Asp Ile Gln Glu Leu 195 200 205 Phe Phe Arg Leu Thr Val Asp Ser Ala Thr Glu Phe Leu Phe Gly Glu 210 215 220 Ser Ala Glu Ser Leu Arg Asp Asp Ser Val Gly Leu Thr Pro Thr Thr 225 230 235 240 Lys Asp Phe Glu Gly Arg Gly Asp Phe Ala Asp Ala Phe Asn Tyr Ser 245 250 255 Gln Thr Tyr Gln Ala Tyr Arg Phe Leu Leu Gln Gln Met Tyr Trp Ile 260 265 270 Leu Asn Gly Ala Glu Phe Arg Lys Ser Ile Ala Ile Val His Lys Phe 275 280 285 Ala Asp His Tyr Val Gln Lys Ala Leu Glu Leu Thr Asp Asp Asp Leu 290 295 300 Gln Lys Gln Asp Gly Tyr Val Phe Leu Tyr Glu Leu Ala Lys Gln Thr 305 310 315 320 Arg Asp Pro Lys Val Leu Arg Asp Gln Leu Leu Asn Ile Leu Val Ala 325 330 335 Gly Arg Asp Thr Thr Ala Gly Leu Leu Ser Phe Val Phe Tyr Glu Leu 340 345 350 Ser Arg Asn Pro Glu Val Phe Ala Lys Leu Arg Glu Glu Val Glu Asn 355 360 365 Arg Phe Gly Leu Gly Glu Glu Ala Arg Val Glu Glu Ile Ser Phe Glu 370 375 380 Ser Leu Lys Ser Cys Glu Tyr Leu Lys Ala Val Ile Asn Glu Ala Leu 385 390 395 400 Arg Leu Tyr Pro Ser Val Pro His Asn Phe Arg Val Ala Thr Arg Asn 405 410 415 Thr Thr Leu Pro Arg Gly Gly Gly Lys Asp Gly Cys Ser Pro Ile Val 420 425 430 Val Lys Lys Gly Gln Val Val Met Tyr Thr Val Ile Gly Thr His Arg 435 440 445 Asp Pro Ser Ile Tyr Gly Ala Asp Ala Asp Val Phe Arg Pro Glu Arg 450 455 460 Trp Phe Glu Pro Glu Thr Arg Lys Leu Gly Trp Ala Tyr Val Pro Phe 465 470 475 480 Asn Gly Gly Pro Arg Ile Cys Leu Gly Gln Gln Phe Ala Leu Thr Glu 485 490 495 Ala Ser Tyr Val Thr Val Arg Leu Leu Gln Glu Phe Gly Asn Leu Ser 500 505 510 Leu Asp Pro Asn Ala Glu Tyr Pro Pro Lys Leu Gln Asn Thr Leu Thr 515 520 525 Leu Ser Leu Phe Asp Gly Ala Asp Val Arg Met Phe 530 535 540 100 517 PRT CANDIDATROPICALIS 100 Met Ile Glu Gln Leu Leu Glu Tyr Trp Tyr Val Val Val Pro Val Leu 1 5 10 15 Tyr Ile Ile Lys Gln Leu Leu Ala Tyr Thr Lys Thr Arg Val Leu Met 20 25 30 Lys Lys Leu Gly Ala Ala Pro Val Thr Asn Lys Leu Tyr Asp Asn Ala 35 40 45 Phe Gly Ile Val Asn Gly Trp Lys Ala Leu Gln Phe Lys Lys Glu Gly 50 55 60 Arg Ala Gln Glu Tyr Asn Asp Tyr Lys Phe Asp His Ser Lys Asn Pro 65 70 75 80 Ser Val Gly Thr Tyr Val Ser Ile Leu Phe Gly Thr Arg Ile Val Val 85 90 95 Thr Lys Asp Pro Glu Asn Ile Lys Ala Ile Leu Ala Thr Gln Phe Gly 100 105 110 Asp Phe Ser Leu Gly Lys Arg His Thr Leu Phe Lys Pro Leu Leu Gly 115 120 125 Asp Gly Ile Phe Thr Leu Asp Gly Glu Gly Trp Lys His Ser Arg Ala 130 135 140 Met Leu Arg Pro Gln Phe Ala Arg Glu Gln Val Ala His Val Thr Ser 145 150 155 160 Leu Glu Pro His Phe Gln Leu Leu Lys Lys His Ile Leu Lys His Lys 165 170 175 Gly Glu Tyr Phe Asp Ile Gln Glu Leu Phe Phe Arg Phe Thr Val Asp 180 185 190 Ser Ala Thr Glu Phe Leu Phe Gly Glu Ser Val His Ser Leu Lys Asp 195 200 205 Glu Ser Ile Gly Ile Asn Gln Asp Asp Ile Asp Phe Ala Gly Arg Lys 210 215 220 Asp Phe Ala Glu Ser Phe Asn Lys Ala Gln Glu Tyr Leu Ala Ile Arg 225 230 235 240 Thr Leu Val Gln Thr Phe Tyr Trp Leu Val Asn Asn Lys Glu Phe Arg 245 250 255 Asp Cys Thr Lys Leu Val His Lys Phe Thr Asn Tyr Tyr Val Gln Lys 260 265 270 Ala Leu Asp Ala Ser Pro Glu Glu Leu Glu Lys Gln Ser Gly Tyr Val 275 280 285 Phe Leu Tyr Glu Leu Val Lys Gln Thr Arg Asp Pro Asn Val Leu Arg 290 295 300 Asp Gln Ser Leu Asn Ile Leu Leu Ala Gly Arg Asp Thr Thr Ala Gly 305 310 315 320 Leu Leu Ser Phe Ala Val Phe Glu Leu Ala Arg His Pro Glu Ile Trp 325 330 335 Ala Lys Leu Arg Glu Glu Ile Glu Gln Gln Phe Gly Leu Gly Glu Asp 340 345 350 Ser Arg Val Glu Glu Ile Thr Phe Glu Ser Leu Lys Arg Cys Glu Tyr 355 360 365 Leu Lys Ala Phe Leu Asn Glu Thr Leu Arg Ile Tyr Pro Ser Val Pro 370 375 380 Arg Asn Phe Arg Ile Ala Thr Lys Asn Thr Thr Leu Pro Arg Gly Gly 385 390 395 400 Gly Ser Asp Gly Thr Ser Pro Ile Leu Ile Gln Lys Gly Glu Ala Val 405 410 415 Ser Tyr Gly Ile Asn Ser Thr His Leu Asp Pro Val Tyr Tyr Gly Pro 420 425 430 Asp Ala Ala Glu Phe Arg Pro Glu Arg Trp Phe Glu Pro Ser Thr Lys 435 440 445 Lys Leu Gly Trp Ala Tyr Leu Pro Phe Asn Gly Gly Pro Arg Ile Cys 450 455 460 Leu Gly Gln Gln Phe Ala Leu Thr Glu Ala Gly Tyr Val Leu Val Arg 465 470 475 480 Leu Val Gln Glu Phe Ser His Val Arg Leu Asp Pro Asp Glu Val Tyr 485 490 495 Pro Pro Lys Arg Leu Thr Asn Leu Thr Met Cys Leu Gln Asp Gly Ala 500 505 510 Ile Val Lys Phe Asp 515 101 517 PRT CANDIDATROPICALIS 101 Met Ile Glu Gln Ile Leu Glu Tyr Trp Tyr Ile Val Val Pro Val Leu 1 5 10 15 Tyr Ile Ile Lys Gln Leu Ile Ala Tyr Ser Lys Thr Arg Val Leu Met 20 25 30 Lys Gln Leu Gly Ala Ala Pro Ile Thr Asn Gln Leu Tyr Asp Asn Val 35 40 45 Phe Gly Ile Val Asn Gly Trp Lys Ala Leu Gln Phe Lys Lys Glu Gly 50 55 60 Arg Ala Gln Glu Tyr Asn Asp His Lys Phe Asp Ser Ser Lys Asn Pro 65 70 75 80 Ser Val Gly Thr Tyr Val Ser Ile Leu Phe Gly Thr Lys Ile Val Val 85 90 95 Thr Lys Asp Pro Glu Asn Ile Lys Ala Ile Leu Ala Thr Gln Phe Gly 100 105 110 Asp Phe Ser Leu Gly Lys Arg His Ala Leu Phe Lys Pro Leu Leu Gly 115 120 125 Asp Gly Ile Phe Thr Leu Asp Gly Glu Gly Trp Lys His Ser Arg Ser 130 135 140 Met Leu Arg Pro Gln Phe Ala Arg Glu Gln Val Ala His Val Thr Ser 145 150 155 160 Leu Glu Pro His Phe Gln Leu Leu Lys Lys His Ile Leu Lys His Lys 165 170 175 Gly Glu Tyr Phe Asp Ile Gln Glu Leu Phe Phe Arg Phe Thr Val Asp 180 185 190 Ser Ala Thr Glu Phe Leu Phe Gly Glu Ser Val His Ser Leu Lys Asp 195 200 205 Glu Thr Ile Gly Ile Asn Gln Asp Asp Ile Asp Phe Ala Gly Arg Lys 210 215 220 Asp Phe Ala Glu Ser Phe Asn Lys Ala Gln Glu Tyr Leu Ser Ile Arg 225 230 235 240 Ile Leu Val Gln Thr Phe Tyr Trp Leu Ile Asn Asn Lys Glu Phe Arg 245 250 255 Asp Cys Thr Lys Leu Val His Lys Phe Thr Asn Tyr Tyr Val Gln Lys 260 265 270 Ala Leu Asp Ala Thr Pro Glu Glu Leu Glu Lys Gln Gly Gly Tyr Val 275 280 285 Phe Leu Tyr Glu Leu Val Lys Gln Thr Arg Asp Pro Lys Val Leu Arg 290 295 300 Asp Gln Ser Leu Asn Ile Leu Leu Ala Gly Arg Asp Thr Thr Ala Gly 305 310 315 320 Leu Leu Ser Phe Ala Val Phe Glu Leu Ala Arg Asn Pro His Ile Trp 325 330 335 Ala Lys Leu Arg Glu Glu Ile Glu Gln Gln Phe Gly Leu Gly Glu Asp 340 345 350 Ser Arg Val Glu Glu Ile Thr Phe Glu Ser Leu Lys Arg Cys Glu Tyr 355 360 365 Leu Lys Ala Phe Leu Asn Glu Thr Leu Arg Val Tyr Pro Ser Val Pro 370 375 380 Arg Asn Phe Arg Ile Ala Thr Lys Asn Thr Thr Leu Pro Arg Gly Gly 385 390 395 400 Gly Pro Asp Gly Thr Gln Pro Ile Leu Ile Gln Lys Gly Glu Gly Val 405 410 415 Ser Tyr Gly Ile Asn Ser Thr His Leu Asp Pro Val Tyr Tyr Gly Pro 420 425 430 Asp Ala Ala Glu Phe Arg Pro Glu Arg Trp Phe Glu Pro Ser Thr Arg 435 440 445 Lys Leu Gly Trp Ala Tyr Leu Pro Phe Asn Gly Gly Pro Arg Ile Cys 450 455 460 Leu Gly Gln Gln Phe Ala Leu Thr Glu Ala Gly Tyr Val Leu Val Arg 465 470 475 480 Leu Val Gln Glu Phe Ser His Ile Arg Leu Asp Pro Asp Glu Val Tyr 485 490 495 Pro Pro Lys Arg Leu Thr Asn Leu Thr Met Cys Leu Gln Asp Gly Ala 500 505 510 Ile Val Lys Phe Asp 515 102 512 PRT CANDIDATROPICALIS 102 Met Leu Asp Gln Ile Leu His Tyr Trp Tyr Ile Val Leu Pro Leu Leu 1 5 10 15 Ala Ile Ile Asn Gln Ile Val Ala His Val Arg Thr Asn Tyr Leu Met 20 25 30 Lys Lys Leu Gly Ala Lys Pro Phe Thr His Val Gln Arg Asp Gly Trp 35 40 45 Leu Gly Phe Lys Phe Gly Arg Glu Phe Leu Lys Ala Lys Ser Ala Gly 50 55 60 Arg Leu Val Asp Leu Ile Ile Ser Arg Phe His Asp Asn Glu Asp Thr 65 70 75 80 Phe Ser Ser Tyr Ala Phe Gly Asn His Val Val Phe Thr Arg Asp Pro 85 90 95 Glu Asn Ile Lys Ala Leu Leu Ala Thr Gln Phe Gly Asp Phe Ser Leu 100 105 110 Gly Ser Arg Val Lys Phe Phe Lys Pro Leu Leu Gly Tyr Gly Ile Phe 115 120 125 Thr Leu Asp Ala Glu Gly Trp Lys His Ser Arg Ala Met Leu Arg Pro 130 135 140 Gln Phe Ala Arg Glu Gln Val Ala His Val Thr Ser Leu Glu Pro His 145 150 155 160 Phe Gln Leu Leu Lys Lys His Ile Leu Lys His Lys Gly Glu Tyr Phe 165 170 175 Asp Ile Gln Glu Leu Phe Phe Arg Phe Thr Val Asp Ser Ala Thr Glu 180 185 190 Phe Leu Phe Gly Glu Ser Val His Ser Leu Lys Asp Glu Glu Ile Gly 195 200 205 Tyr Asp Thr Lys Asp Met Ser Glu Glu Arg Arg Arg Phe Ala Asp Ala 210 215 220 Phe Asn Lys Ser Gln Val Tyr Val Ala Thr Arg Val Ala Leu Gln Asn 225 230 235 240 Leu Tyr Trp Leu Val Asn Asn Lys Glu Phe Lys Glu Cys Asn Asp Ile 245 250 255 Val His Lys Phe Thr Asn Tyr Tyr Val Gln Lys Ala Leu Asp Ala Thr 260 265 270 Pro Glu Glu Leu Glu Lys Gln Gly Gly Tyr Val Phe Leu Tyr Glu Leu 275 280 285 Val Lys Gln Thr Arg Asp Pro Lys Val Leu Arg Asp Gln Ser Leu Asn 290 295 300 Ile Leu Leu Ala Gly Arg Asp Thr Thr Ala Gly Leu Leu Ser Phe Ala 305 310 315 320 Val Phe Glu Leu Ala Arg Asn Pro His Ile Trp Ala Lys Leu Arg Glu 325 330 335 Glu Ile Glu Gln Gln Phe Gly Leu Gly Glu Asp Ser Arg Val Glu Glu 340 345 350 Ile Thr Phe Glu Ser Leu Lys Arg Cys Glu Tyr Leu Lys Ala Val Leu 355 360 365 Asn Glu Thr Leu Arg Leu His Pro Ser Val Pro Arg Asn Ala Arg Phe 370 375 380 Ala Ile Lys Asp Thr Thr Leu Pro Arg Gly Gly Gly Pro Asn Gly Lys 385 390 395 400 Asp Pro Ile Leu Ile Arg Lys Asp Glu Val Val Gln Tyr Ser Ile Ser 405 410 415 Ala Thr Gln Thr Asn Pro Ala Tyr Tyr Gly Ala Asp Ala Ala Asp Phe 420 425 430 Arg Pro Glu Arg Trp Phe Glu Pro Ser Thr Arg Asn Leu Gly Trp Ala 435 440 445 Phe Leu Pro Phe Asn Gly Gly Pro Arg Ile Cys Leu Gly Gln Gln Phe 450 455 460 Ala Leu Thr Glu Ala Gly Tyr Val Leu Val Arg Leu Val Gln Glu Phe 465 470 475 480 Pro Asn Leu Ser Gln Asp Pro Glu Thr Lys Tyr Pro Pro Pro Arg Leu 485 490 495 Ala His Leu Thr Met Cys Leu Phe Asp Gly Ala His Val Lys Met Ser 500 505 510 103 512 PRT CANDIDATROPICALIS 103 Met Leu Asp Gln Ile Phe His Tyr Trp Tyr Ile Val Leu Pro Leu Leu 1 5 10 15 Val Ile Ile Lys Gln Ile Val Ala His Ala Arg Thr Asn Tyr Leu Met 20 25 30 Lys Lys Leu Gly Ala Lys Pro Phe Thr His Val Gln Leu Asp Gly Trp 35 40 45 Phe Gly Phe Lys Phe Gly Arg Glu Phe Leu Lys Ala Lys Ser Ala Gly 50 55 60 Arg Gln Val Asp Leu Ile Ile Ser Arg Phe His Asp Asn Glu Asp Thr 65 70 75 80 Phe Ser Ser Tyr Ala Phe Gly Asn His Val Val Phe Thr Arg Asp Pro 85 90 95 Glu Asn Ile Lys Ala Leu Leu Ala Thr Gln Phe Gly Asp Phe Ser Leu 100 105 110 Gly Ser Arg Val Lys Phe Phe Lys Pro Leu Leu Gly Tyr Gly Ile Phe 115 120 125 Thr Leu Asp Gly Glu Gly Trp Lys His Ser Arg Ala Met Leu Arg Pro 130 135 140 Gln Phe Ala Arg Glu Gln Val Ala His Val Thr Ser Leu Glu Pro His 145 150 155 160 Phe Gln Leu Leu Lys Lys His Ile Leu Lys His Lys Gly Glu Tyr Phe 165 170 175 Asp Ile Gln Glu Leu Phe Phe Arg Phe Thr Val Asp Ser Ala Thr Glu 180 185 190 Phe Leu Phe Gly Glu Ser Val His Ser Leu Arg Asp Glu Glu Ile Gly 195 200 205 Tyr Asp Thr Lys Asp Met Ala Glu Glu Arg Arg Lys Phe Ala Asp Ala 210 215 220 Phe Asn Lys Ser Gln Val Tyr Leu Ser Thr Arg Val Ala Leu Gln Thr 225 230 235 240 Leu Tyr Trp Leu Val Asn Asn Lys Glu Phe Lys Glu Cys Asn Asp Ile 245 250 255 Val His Lys Phe Thr Asn Tyr Tyr Val Gln Lys Ala Leu Asp Ala Thr 260 265 270 Pro Glu Glu Leu Glu Lys Gln Gly Gly Tyr Val Phe Leu Tyr Glu Leu 275 280 285 Ala Lys Gln Thr Lys Asp Pro Asn Val Leu Arg Asp Gln Ser Leu Asn 290 295 300 Ile Leu Leu Ala Gly Arg Asp Thr Thr Ala Gly Leu Leu Ser Phe Ala 305 310 315 320 Val Phe Glu Leu Ala Arg Asn Pro His Ile Trp Ala Lys Leu Arg Glu 325 330 335 Glu Ile Glu Ser His Phe Gly Leu Gly Glu Asp Ser Arg Val Glu Glu 340 345 350 Ile Thr Phe Glu Ser Leu Lys Arg Cys Glu Tyr Leu Lys Ala Val Leu 355 360 365 Asn Glu Thr Leu Arg Leu His Pro Ser Val Pro Arg Asn Ala Arg Phe 370 375 380 Ala Ile Lys Asp Thr Thr Leu Pro Arg Gly Gly Gly Pro Asn Gly Lys 385 390 395 400 Asp Pro Ile Leu Ile Arg Lys Asn Glu Val Val Gln Tyr Ser Ile Ser 405 410 415 Ala Thr Gln Thr Asn Pro Ala Tyr Tyr Gly Ala Asp Ala Ala Asp Phe 420 425 430 Arg Pro Glu Arg Trp Phe Glu Pro Ser Thr Arg Asn Leu Gly Trp Ala 435 440 445 Tyr Leu Pro Phe Asn Gly Gly Pro Arg Ile Cys Leu Gly Gln Gln Phe 450 455 460 Ala Leu Thr Glu Ala Gly Tyr Val Leu Val Arg Leu Val Gln Glu Phe 465 470 475 480 Pro Ser Leu Ser Gln Asp Pro Glu Thr Glu Tyr Pro Pro Pro Arg Leu 485 490 495 Ala His Leu Thr Met Cys Leu Phe Asp Gly Ala Tyr Val Lys Met Gln 500 505 510 104 499 PRT CANDIDATROPICALIS 104 Met Ala Ile Ser Ser Leu Leu Ser Trp Asp Val Ile Cys Val Val Phe 1 5 10 15 Ile Cys Val Cys Val Tyr Phe Gly Tyr Glu Tyr Cys Tyr Thr Lys Tyr 20 25 30 Leu Met His Lys His Gly Ala Arg Glu Ile Glu Asn Val Ile Asn Asp 35 40 45 Gly Phe Phe Gly Phe Arg Leu Pro Leu Leu Leu Met Arg Ala Ser Asn 50 55 60 Glu Gly Arg Leu Ile Glu Phe Ser Val Lys Arg Phe Glu Ser Ala Pro 65 70 75 80 His Pro Gln Asn Lys Thr Leu Val Asn Arg Ala Leu Ser Val Pro Val 85 90 95 Ile Leu Thr Lys Asp Pro Val Asn Ile Lys Ala Met Leu Ser Thr Gln 100 105 110 Phe Asp Asp Phe Ser Leu Gly Leu Arg Leu His Gln Phe Ala Pro Leu 115 120 125 Leu Gly Lys Gly Ile Phe Thr Leu Asp Gly Pro Glu Trp Lys Gln Ser 130 135 140 Arg Ser Met Leu Arg Pro Gln Phe Ala Lys Asp Arg Val Ser His Ile 145 150 155 160 Leu Asp Leu Glu Pro His Phe Val Leu Leu Arg Lys His Ile Asp Gly 165 170 175 His Asn Gly Asp Tyr Phe Asp Ile Gln Glu Leu Tyr Phe Arg Phe Ser 180 185 190 Met Asp Val Ala Thr Gly Phe Leu Phe Gly Glu Ser Val Gly Ser Leu 195 200 205 Lys Asp Glu Asp Ala Arg Phe Leu Glu Ala Phe Asn Glu Ser Gln Lys 210 215 220 Tyr Leu Ala Thr Arg Ala Thr Leu His Glu Leu Tyr Phe Leu Cys Asp 225 230 235 240 Gly Phe Arg Phe Arg Gln Tyr Asn Lys Val Val Arg Lys Phe Cys Ser 245 250 255 Gln Cys Val His Lys Ala Leu Asp Val Ala Pro Glu Asp Thr Ser Glu 260 265 270 Tyr Val Phe Leu Arg Glu Leu Val Lys His Thr Arg Asp Pro Val Val 275 280 285 Leu Gln Asp Gln Ala Leu Asn Val Leu Leu Ala Gly Arg Asp Thr Thr 290 295 300 Ala Ser Leu Leu Ser Phe Ala Thr Phe Glu Leu Ala Arg Asn Asp His 305 310 315 320 Met Trp Arg Lys Leu Arg Glu Glu Val Ile Leu Thr Met Gly Pro Ser 325 330 335 Ser Asp Glu Ile Thr Val Ala Gly Leu Lys Ser Cys Arg Tyr Leu Lys 340 345 350 Ala Ile Leu Asn Glu Thr Leu Arg Leu Tyr Pro Ser Val Pro Arg Asn 355 360 365 Ala Arg Phe Ala Thr Arg Asn Thr Thr Leu Pro Arg Gly Gly Gly Pro 370 375 380 Asp Gly Ser Phe Pro Ile Leu Ile Arg Lys Gly Gln Pro Val Gly Tyr 385 390 395 400 Phe Ile Cys Ala Thr His Leu Asn Glu Lys Val Tyr Gly Asn Asp Ser 405 410 415 His Val Phe Arg Pro Glu Arg Trp Ala Ala Leu Glu Gly Lys Ser Leu 420 425 430 Gly Trp Ser Tyr Leu Pro Phe Asn Gly Gly Pro Arg Ser Cys Leu Gly 435 440 445 Gln Gln Phe Ala Ile Leu Glu Ala Ser Tyr Val Leu Ala Arg Leu Thr 450 455 460 Gln Cys Tyr Thr Thr Ile Gln Leu Arg Thr Thr Glu Tyr Pro Pro Lys 465 470 475 480 Lys Leu Val His Leu Thr Met Ser Leu Leu Asn Gly Val Tyr Ile Arg 485 490 495 Thr Arg Thr 105 1712 DNA Candida tropicalis 105 ggtaccgagc tcacgagttt tgggattttc gagtttggat tgtttccttt gttgattgaa 60 ttgacgaaac cagaggtttt caagacagat aagattgggt ttatcaaaac gcagtttgaa 120 atattccagt tggtttccaa gatatcttga agaagattga cgatttgaaa tttgaagaag 180 tggagaagat ctggtttgga ttgttggaga atttcaagaa tctcaagatt tactctaacg 240 acgggtacaa cgagaattgt attgaattga tcaagaacat gatcttggtg ttacagaaca 300 tcaagttctt ggaccagact gagaatgcca cagatataca aggcgtcatg tgataaaatg 360 gatgagattt atcccacaat tgaagaaaga gtttatggaa agtggtcaac cagaagctaa 420 acaggaagaa gcaaacgaag aggtgaaaca agaagaagaa ggtaaataag tattttgtat 480 tatataacaa acaaagtaag gaatacagat ttatacaata aattgccata ctagtcacgt 540 gagatatctc atccattccc caactcccaa gaaaaaaaaa aagtgaaaaa aaaaatcaaa 600 cccaaagatc aacctcccca tcatcatcgt catcaaaccc ccagctcaat tcgcaatggt 660 tagcacaaaa acatacacag aaagggcatc agcacacccc tccaaggttg cccaacgttt 720 attccgctta atggagtcca aaaagaccaa cctctgcgcc tcgatcgacg tgaccacaac 780 cgccgagttc ctttcgctca tcgacaagct cggtccccac atctgtctcg tgaagacgca 840 catcgatatc atctcagact tcagctacga gggcacgatt gagccgttgc ttgtgcttgc 900 agagcgccac gggttcttga tattcgagga caggaagttt gctgatatcg gaaacaccgt 960 gatgttgcag tacacctcgg gggtataccg gatcgcggcg tggagtgaca tcacgaacgc 1020 gcacggagtg actgggaagg gcgtcgttga agggttgaaa cgcggtgcgg agggggtaga 1080 aaaggaaagg ggcgtgttga tgttggcgga gttgtcgagt aaaggctcgt tggcgcatgg 1140 tgaatatacc cgtgagacga tcgagattgc gaagagtgat cgggagttcg tgattgggtt 1200 catcgcgcag cgggacatgg ggggtagaga agaagggttt gattggatca tcatgacgcc 1260 tggtgtgggg ttggatgata aaggcgatgc gttgggccag cagtatagga ctgttgatga 1320 ggtggttctg actggtaccg atgtgattat tgtcgggaga gggttgtttg gaaaaggaag 1380 agaccctgag gtggagggaa agagatacag ggatgctgga tggaaggcat acttgaagag 1440 aactggtcag ttagaataaa tattgtaata aataggtcta tatacataca ctaagcttct 1500 aggacgtcat tgtagtcttc gaagttgtct gctagtttag ttctcatgat ttcgaaaacc 1560 aataacgcaa tggatgtagc agggatggtg gttagtgcgt tcctgacaaa cccagagtac 1620 gccgcctcaa accacgtcac attcgccctt tgcttcatcc gcatcacttg cttgaaggta 1680 tccacgtacg agttgtaata caccttgaag aa 1712 106 267 PRT CANDIDATROPICALIS 106 Met Val Ser Thr Lys Thr Tyr Thr Glu Arg Ala Ser Ala His Pro Ser 1 5 10 15 Lys Val Ala Gln Arg Leu Phe Arg Leu Met Glu Ser Lys Lys Thr Asn 20 25 30 Leu Cys Ala Ser Ile Asp Val Thr Thr Thr Ala Glu Phe Leu Ser Leu 35 40 45 Ile Asp Lys Leu Gly Pro His Ile Cys Leu Val Lys Thr His Ile Asp 50 55 60 Ile Ile Ser Asp Phe Ser Tyr Glu Gly Thr Ile Glu Pro Leu Leu Val 65 70 75 80 Leu Ala Glu Arg His Gly Phe Leu Ile Phe Glu Asp Arg Lys Phe Ala 85 90 95 Asp Ile Gly Asn Thr Val Met Leu Gln Tyr Thr Ser Gly Val Tyr Arg 100 105 110 Ile Ala Ala Trp Ser Asp Ile Thr Asn Ala His Gly Val Thr Gly Lys 115 120 125 Gly Val Val Glu Gly Leu Lys Arg Gly Ala Glu Gly Val Glu Lys Glu 130 135 140 Arg Gly Val Leu Met Leu Ala Glu Leu Ser Ser Lys Gly Ser Leu Ala 145 150 155 160 His Gly Glu Tyr Thr Arg Glu Thr Ile Glu Ile Ala Lys Ser Asp Arg 165 170 175 Glu Phe Val Ile Gly Phe Ile Ala Gln Arg Asp Met Gly Gly Arg Glu 180 185 190 Glu Gly Phe Asp Trp Ile Ile Met Thr Pro Gly Val Gly Leu Asp Asp 195 200 205 Lys Gly Asp Ala Leu Gly Gln Gln Tyr Arg Thr Val Asp Glu Val Val 210 215 220 Leu Thr Gly Thr Asp Val Ile Ile Val Gly Arg Gly Leu Phe Gly Lys 225 230 235 240 Gly Arg Asp Pro Glu Val Glu Gly Lys Arg Tyr Arg Asp Ala Gly Trp 245 250 255 Lys Ala Tyr Leu Lys Arg Thr Gly Gln Leu Glu 260 265 107 473 DNA Artificial Sequence Description of Artificial Sequence Primer 107 gtcaaagcaa attgttggcc caagcagact cttggaccac cgttgaatgg aacataagcc 60 cagcccaact tcttagtaga tggttcaaac catctttctg gtctgaagtc gttagcgtcc 120 ttaccgtagt attcttccaa acggtgggtc ttgtagacaa cgtaagcaac agtggagcct 180 ttaggaatgt agattgggtc ggtaccgtta gcaccaccac ctcttggcaa agtggtgtct 240 ctggtggcgg ttctaaagtt gacaggaaca gatgggtaca tacgcaaggt ttcgttaagg 300 atagccttca agtattcaca tctcttcaag gcttcgaaag taatttcttc aacgcgggag 360 tcttcaccaa caccaaagtt aacttcgatt tcttctctca acttggacca catctctggg 420 tgtctagcca attcaaacaa agcaaaggac aacaaacccg cggtggtgtc tct 473 108 540 DNA Candida tropicalis 108 tactaacttg ttgaggatct tataaccata cagcaacacg gtcacaacat gtagtagttt 60 gttgaggaac gtatgtgttt ctgagcgcag aactactttt tcaacccacg acgaggtcag 120 tgtttgttca acatgctgtt gcgaaagcca tagcagttac ctaccttccg agaggtcaag 180 ttctttctcc cgtcccgagt tctcatgttg ctaatgttca aactggtgag gttcttgggt 240 tcgcacccgt ggatgcagtc ataagaaaag ccgtggtcct agcagcactg gtttctaggt 300 ctcttatagt ttcgataaaa ccgttgggtc aaaccactaa aaagaaaccc gttctccgtg 360 tgagaaaaat tcggaaacaa tccactaccc tagaagtgta acctgccgct tccgaccttc 420 gtgtcgtctc ggtacaactc tggtgtcaaa cggtctcttg ttcaacgagt acactgcagc 480 aaccttggtg tgaaggtcaa caacttcttc gtataagaat tcgtgttccc acttatgaaa 540 109 29 DNA Bacteriophage T7 109 ggatcctaat acgactcact atagggagg 29 110 523 PRT CANDIDATROPICALIS 110 Met Ala Thr Gln Glu Ile Ile Asp Ser Val Leu Pro Tyr Leu Thr Lys 1 5 10 15 Trp Tyr Thr Val Ile Thr Ala Ala Val Leu Val Phe Leu Ile Ser Thr 20 25 30 Asn Ile Lys Asn Tyr Val Lys Ala Lys Lys Leu Lys Cys Val Asp Pro 35 40 45 Pro Tyr Leu Lys Asp Ala Gly Leu Thr Gly Ile Ser Ser Leu Ile Ala 50 55 60 Ala Ile Lys Ala Lys Asn Asp Gly Arg Leu Ala Asn Phe Ala Asp Glu 65 70 75 80 Val Phe Asp Glu Tyr Pro Asn His Thr Phe Tyr Leu Ser Val Ala Gly 85 90 95 Ala Leu Lys Ile Val Met Thr Val Asp Pro Glu Asn Ile Lys Ala Val 100 105 110 Leu Ala Thr Gln Phe Thr Asp Phe Ser Leu Gly Thr Arg His Ala His 115 120 125 Phe Ala Pro Leu Leu Gly Asp Gly Ile Phe Thr Leu Asp Gly Glu Gly 130 135 140 Trp Lys His Ser Arg Ala Met Leu Arg Pro Gln Phe Ala Arg Asp Gln 145 150 155 160 Ile Gly His Val Lys Ala Leu Glu Pro His Ile Gln Ile Met Ala Lys 165 170 175 Gln Ile Lys Leu Asn Gln Gly Lys Thr Phe Asp Ile Gln Glu Leu Phe 180 185 190 Phe Arg Phe Thr Val Asp Thr Ala Thr Glu Phe Leu Phe Gly Glu Ser 195 200 205 Val His Ser Leu Tyr Asp Glu Lys Leu Gly Ile Pro Thr Pro Asn Glu 210 215 220 Ile Pro Gly Arg Glu Asn Phe Ala Ala Ala Phe Asn Val Ser Gln His 225 230 235 240 Tyr Leu Ala Thr Arg Ser Tyr Ser Gln Thr Phe Tyr Phe Leu Thr Asn 245 250 255 Pro Lys Glu Phe Arg Asp Cys Asn Ala Lys Val His His Leu Ala Lys 260 265 270 Tyr Phe Val Asn Lys Ala Leu Asn Phe Thr Pro Glu Glu Leu Glu Glu 275 280 285 Lys Ser Lys Ser Gly Tyr Val Phe Leu Tyr Glu Leu Val Lys Gln Thr 290 295 300 Arg Asp Pro Lys Val Leu Gln Asp Gln Leu Leu Asn Ile Met Val Ala 305 310 315 320 Gly Arg Asp Thr Thr Ala Gly Leu Leu Ser Phe Ala Leu Phe Glu Leu 325 330 335 Ala Arg His Pro Glu Met Trp Ser Lys Leu Arg Glu Glu Ile Glu Val 340 345 350 Asn Phe Gly Val Gly Glu Asp Ser Arg Val Glu Glu Ile Thr Phe Glu 355 360 365 Ala Leu Lys Arg Cys Glu Tyr Leu Lys Ala Ile Leu Asn Glu Thr Leu 370 375 380 Arg Met Tyr Pro Ser Val Pro Val Asn Phe Arg Thr Ala Thr Arg Asp 385 390 395 400 Thr Thr Leu Pro Arg Gly Gly Gly Ala Asn Gly Thr Asp Pro Ile Tyr 405 410 415 Ile Pro Lys Gly Ser Thr Val Ala Tyr Val Val Tyr Lys Thr His Arg 420 425 430 Leu Glu Glu Tyr Tyr Gly Lys Asp Ala Asn Asp Phe Arg Pro Glu Arg 435 440 445 Trp Phe Glu Pro Ser Thr Lys Lys Leu Gly Trp Ala Tyr Val Pro Phe 450 455 460 Asn Gly Gly Pro Arg Val Cys Leu Gly Gln Gln Phe Ala Leu Thr Glu 465 470 475 480 Ala Ser Tyr Val Ile Thr Arg Leu Ala Gln Met Phe Glu Thr Val Ser 485 490 495 Ser Asp Pro Gly Leu Glu Tyr Pro Pro Pro Lys Cys Ile His Leu Thr 500 505 510 Met Ser His Asn Asp Gly Val Phe Val Lys Met 515 520 111 540 PRT CANDIDATROPICALIS 111 Met Ser Ser Ser Pro Ser Phe Ala Gln Glu Val Leu Ala Thr Thr Ser 1 5 10 15 Pro Tyr Ile Glu Tyr Phe Leu Asp Asn Tyr Thr Arg Trp Tyr Tyr Phe 20 25 30 Ile Pro Leu Val Leu Leu Ser Leu Asn Phe Ile Ser Leu Leu His Thr 35 40 45 Lys Tyr Leu Glu Arg Arg Phe His Ala Lys Pro Leu Gly Asn Val Val 50 55 60 Leu Asp Pro Thr Phe Gly Ile Ala Thr Pro Leu Ile Leu Ile Tyr Leu 65 70 75 80 Lys Ser Lys Gly Thr Val Met Lys Phe Ala Trp Ser Phe Trp Asn Asn 85 90 95 Lys Tyr Ile Val Lys Asp Pro Lys Tyr Lys Thr Thr Gly Leu Arg Ile 100 105 110 Val Gly Leu Pro Leu Ile Glu Thr Ile Asp Pro Glu Asn Ile Lys Ala 115 120 125 Val Leu Ala Thr Gln Phe Asn Asp Phe Ser Leu Gly Thr Arg His Asp 130 135 140 Phe Leu Tyr Ser Leu Leu Gly Asp Gly Ile Phe Thr Leu Asp Gly Ala 145 150 155 160 Gly Trp Lys His Ser Arg Thr Met Leu Arg Pro Gln Phe Ala Arg Glu 165 170 175 Gln Val Ser His Val Lys Leu Leu Glu Pro His Val Gln Val Phe Phe 180 185 190 Lys His Val Arg Lys His Arg Gly Gln Thr Phe Asp Ile Gln Glu Leu 195 200 205 Phe Phe Arg Leu Thr Val Asp Ser Ala Thr Glu Phe Leu Phe Gly Glu 210 215 220 Ser Ala Glu Ser Leu Arg Asp Asp Ser Val Gly Leu Thr Pro Thr Thr 225 230 235 240 Lys Asp Phe Glu Gly Arg Gly Asp Phe Ala Asp Ala Phe Asn Tyr Ser 245 250 255 Gln Thr Tyr Gln Ala Tyr Arg Phe Leu Leu Gln Gln Met Tyr Trp Ile 260 265 270 Leu Asn Gly Ala Glu Phe Arg Lys Ser Ile Ala Ile Val His Lys Phe 275 280 285 Ala Asp His Tyr Val Gln Lys Ala Leu Glu Leu Thr Asp Asp Asp Leu 290 295 300 Gln Lys Gln Asp Gly Tyr Val Phe Leu Tyr Glu Leu Ala Lys Gln Thr 305 310 315 320 Arg Asp Pro Lys Val Leu Arg Asp Gln Leu Leu Asn Ile Leu Val Ala 325 330 335 Gly Arg Asp Thr Thr Ala Gly Leu Leu Ser Phe Val Phe Tyr Glu Leu 340 345 350 Ser Arg Asn Pro Glu Val Phe Ala Lys Leu Arg Glu Glu Val Glu Asn 355 360 365 Arg Phe Gly Leu Gly Glu Glu Ala Arg Val Glu Glu Ile Ser Phe Glu 370 375 380 Ser Leu Lys Ser Cys Glu Tyr Leu Lys Ala Val Ile Asn Glu Ala Leu 385 390 395 400 Arg Leu Tyr Pro Ser Val Pro His Asn Phe Arg Val Ala Thr Arg Asn 405 410 415 Thr Thr Leu Pro Arg Gly Gly Gly Lys Asp Gly Cys Ser Pro Ile Val 420 425 430 Val Lys Lys Gly Gln Val Val Met Tyr Thr Val Ile Gly Thr His Arg 435 440 445 Asp Pro Ser Ile Tyr Gly Ala Asp Ala Asp Val Phe Arg Pro Glu Arg 450 455 460 Trp Phe Glu Pro Glu Thr Arg Lys Leu Gly Trp Ala Tyr Val Pro Phe 465 470 475 480 Asn Gly Gly Pro Arg Ile Cys Leu Gly Gln Gln Phe Ala Leu Thr Glu 485 490 495 Ala Ser Tyr Val Thr Val Arg Leu Leu Gln Glu Phe Gly Asn Leu Ser 500 505 510 Ser Asp Pro Asn Ala Glu Tyr Pro Pro Lys Leu Gln Asn Thr Leu Thr 515 520 525 Leu Ser Leu Phe Asp Gly Ala Asp Val Arg Met Phe 530 535 540 112 517 PRT CANDIDATROPICALIS 112 Met Ile Glu Gln Leu Leu Glu Tyr Trp Tyr Val Val Val Pro Val Leu 1 5 10 15 Tyr Ile Ile Lys Gln Leu Leu Ala Tyr Thr Lys Thr Arg Val Leu Met 20 25 30 Lys Lys Leu Gly Ala Ala Pro Val Thr Asn Lys Leu Tyr Asp Asn Ala 35 40 45 Phe Gly Ile Val Asn Gly Trp Lys Ala Leu Gln Phe Lys Lys Glu Gly 50 55 60 Arg Ala Gln Glu Tyr Asn Asp Tyr Lys Phe Asp His Ser Lys Asn Pro 65 70 75 80 Ser Val Gly Thr Tyr Val Ser Ile Leu Phe Gly Thr Arg Ile Val Val 85 90 95 Thr Lys Asp Pro Glu Asn Ile Lys Ala Ile Leu Ala Thr Gln Phe Gly 100 105 110 Asp Phe Ser Leu Gly Lys Arg His Thr Leu Phe Lys Pro Leu Leu Gly 115 120 125 Asp Gly Ile Phe Thr Leu Asp Gly Glu Gly Trp Lys His Ser Arg Ala 130 135 140 Met Leu Arg Pro Gln Phe Ala Arg Glu Gln Val Ala His Val Thr Ser 145 150 155 160 Leu Glu Pro His Phe Gln Leu Leu Lys Lys His Ile Leu Lys His Lys 165 170 175 Gly Glu Tyr Phe Asp Ile Gln Glu Leu Phe Phe Arg Phe Thr Val Asp 180 185 190 Ser Ala Thr Glu Phe Leu Phe Gly Glu Ser Val His Ser Leu Lys Asp 195 200 205 Glu Ser Ile Gly Ile Asn Gln Asp Asp Ile Asp Phe Ala Gly Arg Lys 210 215 220 Asp Phe Ala Glu Ser Phe Asn Lys Ala Gln Glu Tyr Leu Ala Ile Arg 225 230 235 240 Thr Leu Val Gln Thr Phe Tyr Trp Leu Val Asn Asn Lys Glu Phe Arg 245 250 255 Asp Cys Thr Lys Ser Val His Lys Phe Thr Asn Tyr Tyr Val Gln Lys 260 265 270 Ala Leu Asp Ala Ser Pro Glu Glu Leu Glu Lys Gln Ser Gly Tyr Val 275 280 285 Phe Leu Tyr Glu Leu Val Lys Gln Thr Arg Asp Pro Asn Val Leu Arg 290 295 300 Asp Gln Ser Leu Asn Ile Leu Leu Ala Gly Arg Asp Thr Thr Ala Gly 305 310 315 320 Leu Leu Ser Phe Ala Val Phe Glu Leu Ala Arg His Pro Glu Ile Trp 325 330 335 Ala Lys Leu Arg Glu Glu Ile Glu Gln Gln Phe Gly Leu Gly Glu Asp 340 345 350 Ser Arg Val Glu Glu Ile Thr Phe Glu Ser Leu Lys Arg Cys Glu Tyr 355 360 365 Leu Lys Ala Phe Leu Asn Glu Thr Leu Arg Ile Tyr Pro Ser Val Pro 370 375 380 Arg Asn Phe Arg Ile Ala Thr Lys Asn Thr Thr Leu Pro Arg Gly Gly 385 390 395 400 Gly Ser Asp Gly Thr Ser Pro Ile Leu Ile Gln Lys Gly Glu Ala Val 405 410 415 Ser Tyr Gly Ile Asn Ser Thr His Leu Asp Pro Val Tyr Tyr Gly Pro 420 425 430 Asp Ala Ala Glu Phe Arg Pro Glu Arg Trp Phe Glu Pro Ser Thr Lys 435 440 445 Lys Leu Gly Trp Ala Tyr Leu Pro Phe Asn Gly Gly Pro Arg Ile Cys 450 455 460 Leu Gly Gln Gln Phe Ala Leu Thr Glu Ala Gly Tyr Val Leu Val Arg 465 470 475 480 Leu Val Gln Glu Phe Ser His Val Arg Ser Asp Pro Asp Glu Val Tyr 485 490 495 Pro Pro Lys Arg Leu Thr Asn Leu Thr Met Cys Leu Gln Asp Gly Ala 500 505 510 Ile Val Lys Phe Asp 515 113 517 PRT CANDIDATROPICALIS 113 Met Ile Glu Gln Ile Leu Glu Tyr Trp Tyr Ile Val Val Pro Val Leu 1 5 10 15 Tyr Ile Ile Lys Gln Leu Ile Ala Tyr Ser Lys Thr Arg Val Leu Met 20 25 30 Lys Gln Leu Gly Ala Ala Pro Ile Thr Asn Gln Leu Tyr Asp Asn Val 35 40 45 Phe Gly Ile Val Asn Gly Trp Lys Ala Leu Gln Phe Lys Lys Glu Gly 50 55 60 Arg Ala Gln Glu Tyr Asn Asp His Lys Phe Asp Ser Ser Lys Asn Pro 65 70 75 80 Ser Val Gly Thr Tyr Val Ser Ile Leu Phe Gly Thr Lys Ile Val Val 85 90 95 Thr Lys Asp Pro Glu Asn Ile Lys Ala Ile Leu Ala Thr Gln Phe Gly 100 105 110 Asp Phe Ser Leu Gly Lys Arg His Ala Leu Phe Lys Pro Leu Leu Gly 115 120 125 Asp Gly Ile Phe Thr Leu Asp Gly Glu Gly Trp Lys His Ser Arg Ser 130 135 140 Met Leu Arg Pro Gln Phe Ala Arg Glu Gln Val Ala His Val Thr Ser 145 150 155 160 Leu Glu Pro His Phe Gln Leu Leu Lys Lys His Ile Leu Lys His Lys 165 170 175 Gly Glu Tyr Phe Asp Ile Gln Glu Leu Phe Phe Arg Phe Thr Val Asp 180 185 190 Ser Ala Thr Glu Phe Leu Phe Gly Glu Ser Val His Ser Leu Lys Asp 195 200 205 Glu Thr Ile Gly Ile Asn Gln Asp Asp Ile Asp Phe Ala Gly Arg Lys 210 215 220 Asp Phe Ala Glu Ser Phe Asn Lys Ala Gln Glu Tyr Leu Ser Ile Arg 225 230 235 240 Ile Leu Val Gln Thr Phe Tyr Trp Leu Ile Asn Asn Lys Glu Phe Arg 245 250 255 Asp Cys Thr Lys Ser Val His Lys Phe Thr Asn Tyr Tyr Val Gln Lys 260 265 270 Ala Leu Asp Ala Thr Pro Glu Glu Leu Glu Lys Gln Gly Gly Tyr Val 275 280 285 Phe Leu Tyr Glu Leu Val Lys Gln Thr Arg Asp Pro Lys Val Leu Arg 290 295 300 Asp Gln Ser Leu Asn Ile Leu Leu Ala Gly Arg Asp Thr Thr Ala Gly 305 310 315 320 Leu Leu Ser Phe Ala Val Phe Glu Leu Ala Arg Asn Pro His Ile Trp 325 330 335 Ala Lys Leu Arg Glu Glu Ile Glu Gln Gln Phe Gly Leu Gly Glu Asp 340 345 350 Ser Arg Val Glu Glu Ile Thr Phe Glu Ser Leu Lys Arg Cys Glu Tyr 355 360 365 Leu Lys Ala Phe Leu Asn Glu Thr Leu Arg Val Tyr Pro Ser Val Pro 370 375 380 Arg Asn Phe Arg Ile Ala Thr Lys Asn Thr Thr Leu Pro Arg Gly Gly 385 390 395 400 Gly Pro Asp Gly Thr Gln Pro Ile Leu Ile Gln Lys Gly Glu Gly Val 405 410 415 Ser Tyr Gly Ile Asn Ser Thr His Leu Asp Pro Val Tyr Tyr Gly Pro 420 425 430 Asp Ala Ala Glu Phe Arg Pro Glu Arg Trp Phe Glu Pro Ser Thr Arg 435 440 445 Lys Leu Gly Trp Ala Tyr Leu Pro Phe Asn Gly Gly Pro Arg Ile Cys 450 455 460 Leu Gly Gln Gln Phe Ala Leu Thr Glu Ala Gly Tyr Val Leu Val Arg 465 470 475 480 Leu Val Gln Glu Phe Ser His Ile Arg Ser Asp Pro Asp Glu Val Tyr 485 490 495 Pro Pro Lys Arg Leu Thr Asn Leu Thr Met Cys Leu Gln Asp Gly Ala 500 505 510 0 Ile Val Lys Phe Asp 515 114 512 PRT CANDIDATROPICALIS 114 Met Leu Asp Gln Ile Leu His Tyr Trp Tyr Ile Val Leu Pro Leu Leu 1 5 10 15 Ala Ile Ile Asn Gln Ile Val Ala His Val Arg Thr Asn Tyr Leu Met 20 25 30 Lys Lys Leu Gly Ala Lys Pro Phe Thr His Val Gln Arg Asp Gly Trp 35 40 45 Leu Gly Phe Lys Phe Gly Arg Glu Phe Leu Lys Ala Lys Ser Ala Gly 50 55 60 Arg Ser Val Asp Leu Ile Ile Ser Arg Phe His Asp Asn Glu Asp Thr 65 70 75 80 Phe Ser Ser Tyr Ala Phe Gly Asn His Val Val Phe Thr Arg Asp Pro 85 90 95 Glu Asn Ile Lys Ala Leu Leu Ala Thr Gln Phe Gly Asp Phe Ser Leu 100 105 110 Gly Ser Arg Val Lys Phe Phe Lys Pro Leu Leu Gly Tyr Gly Ile Phe 115 120 125 Thr Leu Asp Ala Glu Gly Trp Lys His Ser Arg Ala Met Leu Arg Pro 130 135 140 Gln Phe Ala Arg Glu Gln Val Ala His Val Thr Ser Leu Glu Pro His 145 150 155 160 Phe Gln Leu Leu Lys Lys His Ile Leu Lys His Lys Gly Glu Tyr Phe 165 170 175 Asp Ile Gln Glu Leu Phe Phe Arg Phe Thr Val Asp Ser Ala Thr Glu 180 185 190 Phe Leu Phe Gly Glu Ser Val His Ser Leu Lys Asp Glu Glu Ile Gly 195 200 205 Tyr Asp Thr Lys Asp Met Ser Glu Glu Arg Arg Arg Phe Ala Asp Ala 210 215 220 Phe Asn Lys Ser Gln Val Tyr Val Ala Thr Arg Val Ala Leu Gln Asn 225 230 235 240 Leu Tyr Trp Leu Val Asn Asn Lys Glu Phe Lys Glu Cys Asn Asp Ile 245 250 255 Val His Lys Phe Thr Asn Tyr Tyr Val Gln Lys Ala Leu Asp Ala Thr 260 265 270 Pro Glu Glu Leu Glu Lys Gln Gly Gly Tyr Val Phe Leu Tyr Glu Leu 275 280 285 Val Lys Gln Thr Arg Asp Pro Lys Val Leu Arg Asp Gln Ser Leu Asn 290 295 300 Ile Leu Leu Ala Gly Arg Asp Thr Thr Ala Gly Leu Leu Ser Phe Ala 305 310 315 320 Val Phe Glu Leu Ala Arg Asn Pro His Ile Trp Ala Lys Leu Arg Glu 325 330 335 Glu Ile Glu Gln Gln Phe Gly Leu Gly Glu Asp Ser Arg Val Glu Glu 340 345 350 Ile Thr Phe Glu Ser Leu Lys Arg Cys Glu Tyr Leu Lys Ala Val Leu 355 360 365 Asn Glu Thr Leu Arg Leu His Pro Ser Val Pro Arg Asn Ala Arg Phe 370 375 380 Ala Ile Lys Asp Thr Thr Leu Pro Arg Gly Gly Gly Pro Asn Gly Lys 385 390 395 400 Asp Pro Ile Leu Ile Arg Lys Asp Glu Val Val Gln Tyr Ser Ile Ser 405 410 415 Ala Thr Gln Thr Asn Pro Ala Tyr Tyr Gly Ala Asp Ala Ala Asp Phe 420 425 430 Arg Pro Glu Arg Trp Phe Glu Pro Ser Thr Arg Asn Leu Gly Trp Ala 435 440 445 Phe Leu Pro Phe Asn Gly Gly Pro Arg Ile Cys Leu Gly Gln Gln Phe 450 455 460 Ala Leu Thr Glu Ala Gly Tyr Val Leu Val Arg Leu Val Gln Glu Phe 465 470 475 480 Pro Asn Leu Ser Gln Asp Pro Glu Thr Lys Tyr Pro Pro Pro Arg Leu 485 490 495 Ala His Leu Thr Met Cys Leu Phe Asp Gly Ala His Val Lys Met Ser 500 505 510 115 512 PRT CANDIDATROPICALIS 115 Met Leu Asp Gln Ile Phe His Tyr Trp Tyr Ile Val Leu Pro Leu Leu 1 5 10 15 Val Ile Ile Lys Gln Ile Val Ala His Ala Arg Thr Asn Tyr Leu Met 20 25 30 Lys Lys Leu Gly Ala Lys Pro Phe Thr His Val Gln Leu Asp Gly Trp 35 40 45 Phe Gly Phe Lys Phe Gly Arg Glu Phe Leu Lys Ala Lys Ser Ala Gly 50 55 60 Arg Gln Val Asp Leu Ile Ile Ser Arg Phe His Asp Asn Glu Asp Thr 65 70 75 80 Phe Ser Ser Tyr Ala Phe Gly Asn His Val Val Phe Thr Arg Asp Pro 85 90 95 Glu Asn Ile Lys Ala Leu Leu Ala Thr Gln Phe Gly Asp Phe Ser Leu 100 105 110 Gly Ser Arg Val Lys Phe Phe Lys Pro Leu Leu Gly Tyr Gly Ile Phe 115 120 125 Thr Leu Asp Gly Glu Gly Trp Lys His Ser Arg Ala Met Leu Arg Pro 130 135 140 Gln Phe Ala Arg Glu Gln Val Ala His Val Thr Ser Leu Glu Pro His 145 150 155 160 Phe Gln Leu Leu Lys Lys His Ile Leu Lys His Lys Gly Glu Tyr Phe 165 170 175 Asp Ile Gln Glu Leu Phe Phe Arg Phe Thr Val Asp Ser Ala Thr Glu 180 185 190 Phe Leu Phe Gly Glu Ser Val His Ser Leu Arg Asp Glu Glu Ile Gly 195 200 205 Tyr Asp Thr Lys Asp Met Ala Glu Glu Arg Arg Lys Phe Ala Asp Ala 210 215 220 Phe Asn Lys Ser Gln Val Tyr Leu Ser Thr Arg Val Ala Leu Gln Thr 225 230 235 240 Leu Tyr Trp Leu Val Asn Asn Lys Glu Phe Lys Glu Cys Asn Asp Ile 245 250 255 Val His Lys Phe Thr Asn Tyr Tyr Val Gln Lys Ala Leu Asp Ala Thr 260 265 270 Pro Glu Glu Leu Glu Lys Gln Gly Gly Tyr Val Phe Leu Tyr Glu Leu 275 280 285 Ala Lys Gln Thr Lys Asp Pro Asn Val Leu Arg Asp Gln Ser Leu Asn 290 295 300 Ile Leu Leu Ala Gly Arg Asp Thr Thr Ala Gly Leu Leu Ser Phe Ala 305 310 315 320 Val Phe Glu Leu Ala Arg Asn Pro His Ile Trp Ala Lys Leu Arg Glu 325 330 335 Glu Ile Glu Ser His Phe Gly Ser Gly Glu Asp Ser Arg Val Glu Glu 340 345 350 Ile Thr Phe Glu Ser Leu Lys Arg Cys Glu Tyr Leu Lys Ala Val Leu 355 360 365 Asn Glu Thr Leu Arg Leu His Pro Ser Val Pro Arg Asn Ala Arg Phe 370 375 380 Ala Ile Lys Asp Thr Thr Leu Pro Arg Gly Gly Gly Pro Asn Gly Lys 385 390 395 400 Asp Pro Ile Leu Ile Arg Lys Asn Glu Val Val Gln Tyr Ser Ile Ser 405 410 415 Ala Thr Gln Thr Asn Pro Ala Tyr Tyr Gly Ala Asp Ala Ala Asp Phe 420 425 430 Arg Pro Glu Arg Trp Phe Glu Pro Ser Thr Arg Asn Leu Gly Trp Ala 435 440 445 Tyr Leu Pro Phe Asn Gly Gly Pro Arg Ile Cys Leu Gly Gln Gln Phe 450 455 460 Ala Leu Thr Glu Ala Gly Tyr Val Leu Val Arg Leu Val Gln Glu Phe 465 470 475 480 Pro Ser Leu Ser Gln Asp Pro Glu Thr Glu Tyr Pro Pro Pro Arg Leu 485 490 495 Ala His Leu Thr Met Cys Leu Phe Asp Gly Ala Tyr Val Lys Met Gln 500 505 510 116 499 PRT CANDIDATROPICALIS 116 Met Ala Ile Ser Ser Leu Leu Ser Trp Asp Val Ile Cys Val Val Phe 1 5 10 15 Ile Cys Val Cys Val Tyr Phe Gly Tyr Glu Tyr Cys Tyr Thr Lys Tyr 20 25 30 Leu Met His Lys His Gly Ala Arg Glu Ile Glu Asn Val Ile Asn Asp 35 40 45 Gly Phe Phe Gly Phe Arg Leu Pro Leu Leu Leu Met Arg Ala Ser Asn 50 55 60 Glu Gly Arg Leu Ile Glu Phe Ser Val Lys Arg Phe Glu Ser Ala Pro 65 70 75 80 His Pro Gln Asn Lys Thr Leu Val Asn Arg Ala Leu Ser Val Pro Val 85 90 95 Ile Leu Thr Lys Asp Pro Val Asn Ile Lys Ala Met Leu Ser Thr Gln 100 105 110 Phe Asp Asp Phe Ser Leu Gly Leu Arg Leu His Gln Phe Ala Pro Leu 115 120 125 Leu Gly Lys Gly Ile Phe Thr Leu Asp Gly Pro Glu Trp Lys Gln Ser 130 135 140 Arg Ser Met Leu Arg Pro Gln Phe Ala Lys Asp Arg Val Ser His Ile 145 150 155 160 Ser Asp Leu Glu Pro His Phe Val Leu Leu Arg Lys His Ile Asp Gly 165 170 175 His Asn Gly Asp Tyr Phe Asp Ile Gln Glu Leu Tyr Phe Arg Phe Ser 180 185 190 Met Asp Val Ala Thr Gly Phe Leu Phe Gly Glu Ser Val Gly Ser Leu 195 200 205 Lys Asp Glu Asp Ala Arg Phe Ser Glu Ala Phe Asn Glu Ser Gln Lys 210 215 220 Tyr Leu Ala Thr Arg Ala Thr Leu His Glu Leu Tyr Phe Leu Cys Asp 225 230 235 240 Gly Phe Arg Phe Arg Gln Tyr Asn Lys Val Val Arg Lys Phe Cys Ser 245 250 255 Gln Cys Val His Lys Ala Leu Asp Val Ala Pro Glu Asp Thr Ser Glu 260 265 270 Tyr Val Phe Leu Arg Glu Leu Val Lys His Thr Arg Asp Pro Val Val 275 280 285 Leu Gln Asp Gln Ala Leu Asn Val Leu Leu Ala Gly Arg Asp Thr Thr 290 295 300 Ala Ser Leu Leu Ser Phe Ala Thr Phe Glu Leu Ala Arg Asn Asp His 305 310 315 320 Met Trp Arg Lys Leu Arg Glu Glu Val Ile Ser Thr Met Gly Pro Ser 325 330 335 Ser Asp Glu Ile Thr Val Ala Gly Leu Lys Ser Cys Arg Tyr Leu Lys 340 345 350 Ala Ile Leu Asn Glu Thr Leu Arg Leu Tyr Pro Ser Val Pro Arg Asn 355 360 365 Ala Arg Phe Ala Thr Arg Asn Thr Thr Leu Pro Arg Gly Gly Gly Pro 370 375 380 Asp Gly Ser Phe Pro Ile Leu Ile Arg Lys Gly Gln Pro Val Gly Tyr 385 390 395 400 Phe Ile Cys Ala Thr His Leu Asn Glu Lys Val Tyr Gly Asn Asp Ser 405 410 415 His Val Phe Arg Pro Glu Arg Trp Ala Ala Leu Glu Gly Lys Ser Leu 420 425 430 Gly Trp Ser Tyr Leu Pro Phe Asn Gly Gly Pro Arg Ser Cys Leu Gly 435 440 445 Gln Gln Phe Ala Ile Leu Glu Ala Ser Tyr Val Leu Ala Arg Leu Thr 450 455 460 Gln Cys Tyr Thr Thr Ile Gln Leu Arg Thr Thr Glu Tyr Pro Pro Lys 465 470 475 480 Lys Leu Val His Leu Thr Met Ser Leu Leu Asn Gly Val Tyr Ile Arg 485 490 495 Thr Arg Thr 117 679 PRT CANDIDATROPICALIS 117 Met Ala Leu Asp Lys Leu Asp Leu Tyr Val Ile Ile Thr Leu Val Val 1 5 10 15 Ala Val Ala Ala Tyr Phe Ala Lys Asn Gln Phe Leu Asp Gln Pro Gln 20 25 30 Asp Thr Gly Phe Leu Asn Thr Asp Ser Gly Ser Asn Ser Arg Asp Val 35 40 45 Leu Ser Thr Leu Lys Lys Asn Asn Lys Asn Thr Leu Leu Leu Phe Gly 50 55 60 Ser Gln Thr Gly Thr Ala Glu Asp Tyr Ala Asn Lys Leu Ser Arg Glu 65 70 75 80 Leu His Ser Arg Phe Gly Leu Lys Thr Met Val Ala Asp Phe Ala Asp 85 90 95 Tyr Asp Trp Asp Asn Phe Gly Asp Ile Thr Glu Asp Ile Leu Val Phe 100 105 110 Phe Ile Val Ala Thr Tyr Gly Glu Gly Glu Pro Thr Asp Asn Ala Asp 115 120 125 Glu Phe His Thr Trp Leu Thr Glu Glu Ala Asp Thr Leu Ser Thr Leu 130 135 140 Lys Tyr Thr Val Phe Gly Leu Gly Asn Ser Thr Tyr Glu Phe Phe Asn 145 150 155 160 Ala Ile Gly Arg Lys Phe Asp Arg Leu Leu Ser Glu Lys Gly Gly Asp 165 170 175 Arg Phe Ala Glu Tyr Ala Glu Gly Asp Asp Gly Thr Gly Thr Leu Asp 180 185 190 Glu Asp Phe Met Ala Trp Lys Asp Asn Val Phe Asp Ala Leu Lys Asn 195 200 205 Asp Leu Asn Phe Glu Glu Lys Glu Leu Lys Tyr Glu Pro Asn Val Lys 210 215 220 Leu Thr Glu Arg Asp Asp Leu Ser Ala Ala Asp Ser Gln Val Ser Leu 225 230 235 240 Gly Glu Pro Asn Lys Lys Tyr Ile Asn Ser Glu Gly Ile Asp Leu Thr 245 250 255 Lys Gly Pro Phe Asp His Thr His Pro Tyr Leu Ala Arg Ile Thr Glu 260 265 270 Thr Arg Glu Leu Phe Ser Ser Lys Asp Arg His Cys Ile His Val Glu 275 280 285 Phe Asp Ile Ser Glu Ser Asn Leu Lys Tyr Thr Thr Gly Asp His Leu 290 295 300 Ala Ile Trp Pro Ser Asn Ser Asp Glu Asn Ile Lys Gln Phe Ala Lys 305 310 315 320 Cys Phe Gly Leu Glu Asp Lys Leu Asp Thr Val Ile Glu Leu Lys Ala 325 330 335 Leu Asp Ser Thr Tyr Thr Ile Pro Phe Pro Thr Pro Ile Thr Tyr Gly 340 345 350 Ala Val Ile Arg His His Leu Glu Ile Ser Gly Pro Val Ser Arg Gln 355 360 365 Phe Phe Leu Ser Ile Ala Gly Phe Ala Pro Asp Glu Glu Thr Lys Lys 370 375 380 Ala Phe Thr Arg Leu Gly Gly Asp Lys Gln Glu Phe Ala Ala Lys Val 385 390 395 400 Thr Arg Arg Lys Phe Asn Ile Ala Asp Ala Leu Leu Tyr Ser Ser Asn 405 410 415 Asn Ala Pro Trp Ser Asp Val Pro Phe Glu Phe Leu Ile Glu Asn Val 420 425 430 Pro His Leu Thr Pro Arg Tyr Tyr Ser Ile Ser Ser Ser Ser Leu Ser 435 440 445 Glu Lys Gln Leu Ile Asn Val Thr Ala Val Val Glu Ala Glu Glu Glu 450 455 460 Ala Asp Gly Arg Pro Val Thr Gly Val Val Thr Asn Leu Leu Lys Asn 465 470 475 480 Val Glu Ile Val Gln Asn Lys Thr Gly Glu Lys Pro Leu Val His Tyr 485 490 495 Asp Leu Ser Gly Pro Arg Gly Lys Phe Asn Lys Phe Lys Leu Pro Val 500 505 510 His Val Arg Arg Ser Asn Phe Lys Leu Pro Lys Asn Ser Thr Thr Pro 515 520 525 Val Ile Leu Ile Gly Pro Gly Thr Gly Val Ala Pro Leu Arg Gly Phe 530 535 540 Val Arg Glu Arg Val Gln Gln Val Lys Asn Gly Val Asn Val Gly Lys 545 550 555 560 Thr Leu Leu Phe Tyr Gly Cys Arg Asn Ser Asn Glu Asp Phe Leu Tyr 565 570 575 Lys Gln Glu Trp Ala Glu Tyr Ala Ser Val Leu Gly Glu Asn Phe Glu 580 585 590 Met Phe Asn Ala Phe Ser Arg Gln Asp Pro Ser Lys Lys Val Tyr Val 595 600 605 Gln Asp Lys Ile Leu Glu Asn Ser Gln Leu Val His Glu Leu Leu Thr 610 615 620 Glu Gly Ala Ile Ile Tyr Val Cys Gly Asp Ala Ser Arg Met Ala Arg 625 630 635 640 Asp Val Gln Thr Thr Ile Ser Lys Ile Val Ala Lys Ser Arg Glu Ile 645 650 655 Ser Glu Asp Lys Ala Ala Glu Leu Val Lys Ser Trp Lys Val Gln Asn 660 665 670 Arg Tyr Gln Glu Asp Val Trp 675 118 679 PRT CANDIDATROPICALIS 118 Met Ala Leu Asp Lys Leu Asp Leu Tyr Val Ile Ile Thr Leu Val Val 1 5 10 15 Ala Val Ala Ala Tyr Phe Ala Lys Asn Gln Phe Leu Asp Gln Pro Gln 20 25 30 Asp Thr Gly Phe Leu Asn Thr Asp Ser Gly Ser Asn Ser Arg Asp Val 35 40 45 Leu Ser Thr Leu Lys Lys Asn Asn Lys Asn Thr Leu Leu Leu Phe Gly 50 55 60 Ser Gln Thr Gly Thr Ala Glu Asp Tyr Ala Asn Lys Leu Ser Arg Glu 65 70 75 80 Leu His Ser Arg Phe Gly Leu Lys Thr Met Val Ala Asp Phe Ala Asp 85 90 95 Tyr Asp Trp Asp Asn Phe Gly Asp Ile Thr Glu Asp Ile Leu Val Phe 100 105 110 Phe Ile Val Ala Thr Tyr Gly Glu Gly Glu Pro Thr Asp Asn Ala Asp 115 120 125 Glu Phe His Thr Trp Leu Thr Glu Glu Ala Asp Thr Leu Ser Thr Leu 130 135 140 Arg Tyr Thr Val Phe Gly Leu Gly Asn Ser Thr Tyr Glu Phe Phe Asn 145 150 155 160 Ala Ile Gly Arg Lys Phe Asp Arg Leu Leu Ser Glu Lys Gly Gly Asp 165 170 175 Arg Phe Ala Glu Tyr Ala Glu Gly Asp Asp Gly Thr Gly Thr Leu Asp 180 185 190 Glu Asp Phe Met Ala Trp Lys Asp Asn Val Phe Asp Ala Leu Lys Asn 195 200 205 Asp Leu Asn Phe Glu Glu Lys Glu Leu Lys Tyr Glu Pro Asn Val Lys 210 215 220 Leu Thr Glu Arg Asp Asp Leu Ser Ala Ala Asp Ser Gln Val Ser Leu 225 230 235 240 Gly Glu Pro Asn Lys Lys Tyr Ile Asn Ser Glu Gly Ile Asp Leu Thr 245 250 255 Lys Gly Pro Phe Asp His Thr His Pro Tyr Leu Ala Arg Ile Thr Glu 260 265 270 Thr Arg Glu Leu Phe Ser Ser Lys Glu Arg His Cys Ile His Val Glu 275 280 285 Phe Asp Ile Ser Glu Ser Asn Leu Lys Tyr Thr Thr Gly Asp His Leu 290 295 300 Ala Ile Trp Pro Ser Asn Ser Asp Glu Asn Ile Lys Gln Phe Ala Lys 305 310 315 320 Cys Phe Gly Leu Glu Asp Lys Leu Asp Thr Val Ile Glu Leu Lys Ala 325 330 335 Leu Asp Ser Thr Tyr Thr Ile Pro Phe Pro Thr Pro Ile Thr Tyr Gly 340 345 350 Ala Val Ile Arg His His Leu Glu Ile Ser Gly Pro Val Ser Arg Gln 355 360 365 Phe Phe Leu Ser Ile Ala Gly Phe Ala Pro Asp Glu Glu Thr Lys Lys 370 375 380 Thr Phe Thr Arg Leu Gly Gly Asp Lys Gln Glu Phe Ala Thr Lys Val 385 390 395 400 Thr Arg Arg Lys Phe Asn Ile Ala Asp Ala Leu Leu Tyr Ser Ser Asn 405 410 415 Asn Thr Pro Trp Ser Asp Val Pro Phe Glu Phe Leu Ile Glu Asn Ile 420 425 430 Gln His Leu Thr Pro Arg Tyr Tyr Ser Ile Ser Ser Ser Ser Leu Ser 435 440 445 Glu Lys Gln Leu Ile Asn Val Thr Ala Val Val Glu Ala Glu Glu Glu 450 455 460 Ala Asp Gly Arg Pro Val Thr Gly Val Val Thr Asn Leu Leu Lys Asn 465 470 475 480 Ile Glu Ile Ala Gln Asn Lys Thr Gly Glu Lys Pro Leu Val His Tyr 485 490 495 Asp Leu Ser Gly Pro Arg Gly Lys Phe Asn Lys Phe Lys Leu Pro Val 500 505 510 His Val Arg Arg Ser Asn Phe Lys Leu Pro Lys Asn Ser Thr Thr Pro 515 520 525 Val Ile Leu Ile Gly Pro Gly Thr Gly Val Ala Pro Leu Arg Gly Phe 530 535 540 Val Arg Glu Arg Val Gln Gln Val Lys Asn Gly Val Asn Val Gly Lys 545 550 555 560 Thr Leu Leu Phe Tyr Gly Cys Arg Asn Ser Asn Glu Asp Phe Leu Tyr 565 570 575 Lys Gln Glu Trp Ala Glu Tyr Ala Ser Val Leu Gly Glu Asn Phe Glu 580 585 590 Met Phe Asn Ala Phe Ser Arg Gln Asp Pro Ser Lys Lys Val Tyr Val 595 600 605 Gln Asp Lys Ile Leu Glu Asn Ser Gln Leu Val His Glu Leu Leu Thr 610 615 620 Glu Gly Ala Ile Ile Tyr Val Cys Gly Asp Ala Ser Arg Met Ala Arg 625 630 635 640 Asp Val Gln Thr Thr Ile Ser Lys Ile Val Ala Lys Ser Arg Glu Ile 645 650 655 Ser Glu Asp Lys Ala Ala Glu Leu Val Lys Ser Trp Lys Val Gln Asn 660 665 670 Arg Tyr Gln Glu Asp Val Trp 675 

What is claimed is:
 1. A method of transmitting digital information comprising the steps of: forward error correcting a plurality of bits of digital information using complementary pattern-mapped convolutional codes; modulating a plurality of carrier signals with the forward error corrected bits; and transmitting the carrier signals.
 2. A method according to claim 1, wherein the step of forward error correcting the bits comprises the steps of: defining a plurality of code partitions; finding noncatastrophic partition codes; and mapping the noncatastrophic codes to a QAM constellation.
 3. A method according to claim 2, wherein the step of modulating a plurality of carrier signals with the forward error corrected bits comprises the step of: independently amplitude shift keying in-phase and quadrature components of the QAM constellation.
 4. A method according to claim 3, wherein the step of amplitude shift keying in-phase and quadrature components of the QAM constellation uses Gray code mapped constellation points corresponding to a plurality of amplitude levels.
 5. A method according to claim 4, further comprising the steps of: assessing the relative value of code bits to be mapped to the constellation points; and assigning more valuable bits to most significant bits in the constellation points.
 6. A method according to claim 2, wherein the partition codes comprise punctured codes.
 7. A method according to claim 1, wherein the code partitions comprise an upper main partition, a lower main partition, an upper backup partition, and a lower backup partition, wherein the upper main partition and the lower main partition do not overlap, the upper backup partition and the lower backup partitions do not overlap, the upper backup partition overlaps first portions of both the upper main partition and the lower main partition, and the lower backup partition overlaps second portions of both the upper main partition and the lower main partition.
 8. A method according to claim 1, wherein the step of forward error correcting the bits comprises the steps of: deleting predetermined bits in the plurality of bits to produce a modified plurality of bits; allocating the modified plurality of bits among a plurality of partitions; mapping in-phase and quadrature components of the modified plurality of bits to a QAM constellation; independently amplitude shift keying in-phase and quadrature components of the QAM constellation using Gray code mapped constellation points corresponding to a plurality of amplitude levels; assessing the relative value of code bits to be mapped to the constellation points; and assigning more valuable bits to most significant bits in the constellation points.
 9. A method according to claim 8, wherein the code partitions comprise an upper main partition, a lower main partition, an upper backup partition, and a lower backup partition, wherein the upper main partition and the lower main partition do not overlap, the upper backup partition and the lower backup partitions do not overlap, the upper backup partition overlaps first portions of both the upper main partition and the lower main partition, and the lower backup partition overlaps second portions of both the upper main partition and the lower main partition.
 10. A transmitter comprising: means for forward error correcting a plurality of bits of digital information using complementary pattern-mapped convolutional codes; means for modulating a plurality of carrier signals with the forward error corrected bits; and means for transmitting the carrier signals.
 11. A transmitter according to claim 10, wherein the complementary pattern-mapped convolutional codes comprise: a plurality of noncatastrophic partition codes mapped to a QAM constellation.
 12. A transmitter according to claim 10, wherein the means for modulating a plurality of carrier signals with the forward error corrected bits comprises: means for independently amplitude shift keying in-phase and quadrature components of the QAM constellation.
 13. A transmitter according to claim 12, wherein the means for independently amplitude shift keying in-phase and quadrature components of the QAM constellation uses Gray code mapped constellation points corresponding to a plurality of amplitude levels.
 14. A transmitter according to claim 10, wherein the means for forward error correcting the bits comprises: means for deleting predetermined bits in the plurality of bits to produce a modified plurality of bits; means for allocating the modified plurality of bits among a plurality of partitions; and means for mapping in-phase and quadrature components of the modified plurality of bits to a QAM constellation.
 15. A method of receiving an information signal comprising the steps of: receiving a plurality of carrier signals modulated by a plurality of complementary pattern-mapped convolutional coded bits; demodulating the carrier signals to recover the complementary pattern-mapped convolutional coded bits; and producing an output signal based on the complementary pattern-mapped convolutional coded bits.
 16. A method according to claim 15, wherein the step of demodulating the carrier signals comprises the steps of: passing the complementary pattern-mapped convolutional coded bits through a nonlinear limiter.
 17. A receiver for receiving an information signal comprising: means for receiving a plurality of carrier signals modulated by a plurality of complementary pattern-mapped convolutional coded bits; means for demodulating the carrier signals to recover the complementary pattern-mapped convolutional coded bits; and means for producing an output signal based on the complementary pattern-mapped convolutional coded bits.
 18. A receiver according to claim 17, wherein the means for demodulating the carrier signals comprises: means for passing the complementary pattern-mapped convolutional coded bits through a nonlinear limiter. 